BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is fabG [H]

Identifier: 238894437

GI number: 238894437

Start: 2330550

End: 2331353

Strand: Reverse

Name: fabG [H]

Synonym: KP1_2425

Alternate gene names: 238894437

Gene position: 2331353-2330550 (Counterclockwise)

Preceding gene: 238894439

Following gene: 238894435

Centisome position: 44.42

GC content: 64.3

Gene sequence:

>804_bases
GTGAGCCTCTCCTATTGTAAGGACTCCACATACCAGAGAGGACCGAACATGACTAAAATTGCACTTATTACCGGCGCCAA
CCGCGGCCTTGGCCGTCAGACTGCACTGGATATCGCCCGCCAGGGTGGGGATGTCATCGTCACCTACCGCGGCAGTCTCG
AACAGGCGGAAGCGGTGGTCGCCGACATCCGCGCCCTGGGCCGCAAGGCCATCGCCCTACCGCTGGATATGGCGCAAACC
GCCAGCTTCCCGGCCTTCGCCGACAGCCTCGGCAGCGCGCTGGCCAGCGTCTGGGGGCGGGCCACTTTCGACCACCTGAT
CAATAACGCAGGGCACGGCGAATTCGCCCCGCTGGCCGAAACGCGCGAAGCGCAGTTCGACGGGCTGTTTAACGTCCACG
TTAAGGGGGTATTTTTCCTCGTACAAACCCTGCTGCCGCTGCTGGCAGACGGCGGGCGGATCGTTAACTTTTCCTCCGGG
CTGACCCGCGTCTCCTATCCTGGCTTCTCCGCCTACGCCGCCGCCAAAGCGGCTGTGGAGATGCTGAGCGTGTACATGGC
CCGCGAGCTGGGCGGGCGCGGCATCACCGTCAATACCATCGCCCCCGGCGCTATCGCCACCGATTTTGGCGGTGGGCTGG
TGCGGGACGACGCAGAGGTAAACGCGCAGTTTGCCGCCATGACGGCGCTGGGACGGGTGGGCGTTCCCGAGGATATTGGG
CCGATGATCGCCAGCCTGCTACGCGACGATAACCGCTGGGTAACCGCCCAGCGGATCGAGGTGTCGGGCGGACAAACCAT
CTGA

Upstream 100 bases:

>100_bases
CAGGCAAGTTTTAAAGCCTGAGTATGCGCTATTTCCCGGCAAAAGGGAGTGAACGGAGAGAAATGGGCAAAAAATAACAA
GGATTGGGCAACCCGGCCCG

Downstream 100 bases:

>100_bases
CGACTCAGGCTGGCAGGATGCGCTCCAGCGCCAGGCCTGCCAGCCGCACGGTCTCCAGAAGACGCGGCAGACTATCCCCT
TCCCGCGCTTTCGCCGACAG

Product: putative dehydrogenase/reductase oxidoreductase protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSLSYCKDSTYQRGPNMTKIALITGANRGLGRQTALDIARQGGDVIVTYRGSLEQAEAVVADIRALGRKAIALPLDMAQT
ASFPAFADSLGSALASVWGRATFDHLINNAGHGEFAPLAETREAQFDGLFNVHVKGVFFLVQTLLPLLADGGRIVNFSSG
LTRVSYPGFSAYAAAKAAVEMLSVYMARELGGRGITVNTIAPGAIATDFGGGLVRDDAEVNAQFAAMTALGRVGVPEDIG
PMIASLLRDDNRWVTAQRIEVSGGQTI

Sequences:

>Translated_267_residues
MSLSYCKDSTYQRGPNMTKIALITGANRGLGRQTALDIARQGGDVIVTYRGSLEQAEAVVADIRALGRKAIALPLDMAQT
ASFPAFADSLGSALASVWGRATFDHLINNAGHGEFAPLAETREAQFDGLFNVHVKGVFFLVQTLLPLLADGGRIVNFSSG
LTRVSYPGFSAYAAAKAAVEMLSVYMARELGGRGITVNTIAPGAIATDFGGGLVRDDAEVNAQFAAMTALGRVGVPEDIG
PMIASLLRDDNRWVTAQRIEVSGGQTI
>Mature_266_residues
SLSYCKDSTYQRGPNMTKIALITGANRGLGRQTALDIARQGGDVIVTYRGSLEQAEAVVADIRALGRKAIALPLDMAQTA
SFPAFADSLGSALASVWGRATFDHLINNAGHGEFAPLAETREAQFDGLFNVHVKGVFFLVQTLLPLLADGGRIVNFSSGL
TRVSYPGFSAYAAAKAAVEMLSVYMARELGGRGITVNTIAPGAIATDFGGGLVRDDAEVNAQFAAMTALGRVGVPEDIGP
MIASLLRDDNRWVTAQRIEVSGGQTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=28.0155642023346, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=30.1960784313725, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI225579078, Length=210, Percent_Identity=34.2857142857143, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI119392083, Length=205, Percent_Identity=33.1707317073171, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=28.4552845528455, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=25.8687258687259, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=25, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=27.6, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI166795268, Length=216, Percent_Identity=30.0925925925926, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789378, Length=267, Percent_Identity=32.9588014981273, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=32.6693227091633, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=29.718875502008, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=31.4516129032258, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI2367175, Length=260, Percent_Identity=32.3076923076923, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=33.4677419354839, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790717, Length=223, Percent_Identity=28.2511210762332, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=29.1828793774319, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=33.8383838383838, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=28.6821705426357, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=30.1587301587302, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=24.6153846153846, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=225, Percent_Identity=26.2222222222222, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=30.9433962264151, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=31.0606060606061, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=28.6274509803922, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=31.9852941176471, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.8804780876494, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=28.6274509803922, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=25.9842519685039, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=29.368029739777, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.0769230769231, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=33.6734693877551, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=28.8389513108614, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=28.3464566929134, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=26.4591439688716, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.4090909090909, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=29.1044776119403, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=30.7984790874525, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=27.6515151515151, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=202, Percent_Identity=26.7326732673267, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.5151515151515, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=28.4584980237154, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=29.0566037735849, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=27.4809160305344, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=217, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17558990, Length=217, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=26.5917602996255, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=208, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=30.1020408163265, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=33.0708661417323, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=32.5301204819277, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32.4, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=33.0739299610895, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.5882352941176, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=26.6932270916335, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=27.3764258555133, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=30.8080808080808, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644337, Length=172, Percent_Identity=33.1395348837209, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28137; Mature: 28006

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSYCKDSTYQRGPNMTKIALITGANRGLGRQTALDIARQGGDVIVTYRGSLEQAEAVV
CCCCCCCCCCHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHH
ADIRALGRKAIALPLDMAQTASFPAFADSLGSALASVWGRATFDHLINNAGHGEFAPLAE
HHHHHHCCCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
TREAQFDGLFNVHVKGVFFLVQTLLPLLADGGRIVNFSSGLTRVSYPGFSAYAAAKAAVE
HHHHHHCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHH
MLSVYMARELGGRGITVNTIAPGAIATDFGGGLVRDDAEVNAQFAAMTALGRVGVPEDIG
HHHHHHHHHHCCCCEEEEEECCCCEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHH
PMIASLLRDDNRWVTAQRIEVSGGQTI
HHHHHHHHCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure 
SLSYCKDSTYQRGPNMTKIALITGANRGLGRQTALDIARQGGDVIVTYRGSLEQAEAVV
CCCCCCCCCHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHH
ADIRALGRKAIALPLDMAQTASFPAFADSLGSALASVWGRATFDHLINNAGHGEFAPLAE
HHHHHHCCCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
TREAQFDGLFNVHVKGVFFLVQTLLPLLADGGRIVNFSSGLTRVSYPGFSAYAAAKAAVE
HHHHHHCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHH
MLSVYMARELGGRGITVNTIAPGAIATDFGGGLVRDDAEVNAQFAAMTALGRVGVPEDIG
HHHHHHHHHHCCCCEEEEEECCCCEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHH
PMIASLLRDDNRWVTAQRIEVSGGQTI
HHHHHHHHCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]