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The map label for this gene is icfG [H]

Identifier: 238894401

GI number: 238894401

Start: 2291354

End: 2292568

Strand: Direct

Name: icfG [H]

Synonym: KP1_2384

Alternate gene names: 238894401

Gene position: 2291354-2292568 (Clockwise)

Preceding gene: 238894400

Following gene: 238894402

Centisome position: 43.66

GC content: 59.92

Gene sequence:

>1215_bases
ATGTCGGCACAGCACGTCCTGATTGTTGAAGATTCGCTGGTTTATCGTCGGCTGCTAAGCCGAATGTTGACGCAGTGGGG
TTATATCGTTAGTGAGGCGGAAAACGGCGTCGACGCGCTGGCGATCCTGGAAAACCAGCCTGTCAGCCTGGTGATAAGCG
ACTGGGAGATGCCGGAGATGAATGGCCTGACGCTATGTCGGGAAATTCGCCGTCGCCAGTTTGGTCGCTATGTTTATCTG
ATATTGCTCACCGCCCGCGAAGACCCTGGCGATTTAACGCAGGGGTTTGAGGCAGGGGCCGATGATTTTCTCAGCAAACC
GGTAGAGCAGAGCGAGCTGCGGGCGCGGCTGCACGCCGGGGCGCGGATCCTCTCCCTTGAAGCCGACCTCGCCGCGCGCA
ATACGCGGCTAAGTGAAGCGCTGCGGCAGATTGAACAGGATCTGGAGCTGGCGGCGCGCATTCAGCAATCGGTTCTCCCG
GCTCATCAGCTGTGCTATCAGGGTTTTTTCTCCGACTGGATTTTCCTGCCGTCGGCCTGGGTATCGGGGGATATTTTTAA
TGTGTTCCCGCTGGGGGAGCATCTCGGATTTTACTGCGTGGATGTCTCCGGACACGGCGTGGGGGCGGCGATGATGTCGC
TCGCCGTCGCCCGCCAGTTTTTGCATGGCAGGGCCGTTGAGCGCTTTCTTTTTACGGCAGACAACCAGCCGGCGTCGCCG
GCCGAGGTGGTGGCGATCCTCAATGGTCGTTTTTGCAGTGACGAAACAGAGATCGTCAGCTATTTCACGTTGATCTATGG
CGTGATCGACCTGCAGACCGGTGCGGGCAAACTCTGTCAGGCCGGGCATCCCACGCCTTTTATCGTTAGCCCGGACGCTA
CCGTCCGCCCGGTCGGCAGCGGCGGGGCGCCGGTGGGGTTGATAGACCATCTCTCGTGGGCAGATGTCAGTTTTTCGCTG
GCGCCGGGAGAGCGGCTGTGCCTGTTCAGCGACGGTATCACCGAATGTGAAAACCGGAGCGGTGAACAGTTTGGCGAGGC
GCGCTTGCAAGCGTGGCTGCAGGACAGCGTGACGCAGCCGCTGCCCGCGCTGCTGCCGCGTTTTGCCCGGCACCTGATCC
GCTGGCGCAGTGGCGACGCGCAGGAGACCCAGGCGATGGCCGATGATGTTTCACTCTTGATTATTGAACGTACAGGGGAC
AGTGATGAAAATTGA

Upstream 100 bases:

>100_bases
ACTATGCCGGTACCCGCTACCCGAGGCATGACAGCGGCAGCGGCAAGTTTCGTGAAGGCACGATCAGCCTTATCTGGTTC
TTGCCGATTTAGGAGGCGCG

Downstream 100 bases:

>100_bases
AACTGAACGGCAGGCCTCGGTGACGATCCTGACGCCGGCGGTGCGTCGGCTGGATGCTTCCGTCGCGGTAGCCTTTAAGG
CGGCAATCGCCCAGGAGATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSAQHVLIVEDSLVYRRLLSRMLTQWGYIVSEAENGVDALAILENQPVSLVISDWEMPEMNGLTLCREIRRRQFGRYVYL
ILLTAREDPGDLTQGFEAGADDFLSKPVEQSELRARLHAGARILSLEADLAARNTRLSEALRQIEQDLELAARIQQSVLP
AHQLCYQGFFSDWIFLPSAWVSGDIFNVFPLGEHLGFYCVDVSGHGVGAAMMSLAVARQFLHGRAVERFLFTADNQPASP
AEVVAILNGRFCSDETEIVSYFTLIYGVIDLQTGAGKLCQAGHPTPFIVSPDATVRPVGSGGAPVGLIDHLSWADVSFSL
APGERLCLFSDGITECENRSGEQFGEARLQAWLQDSVTQPLPALLPRFARHLIRWRSGDAQETQAMADDVSLLIIERTGD
SDEN

Sequences:

>Translated_404_residues
MSAQHVLIVEDSLVYRRLLSRMLTQWGYIVSEAENGVDALAILENQPVSLVISDWEMPEMNGLTLCREIRRRQFGRYVYL
ILLTAREDPGDLTQGFEAGADDFLSKPVEQSELRARLHAGARILSLEADLAARNTRLSEALRQIEQDLELAARIQQSVLP
AHQLCYQGFFSDWIFLPSAWVSGDIFNVFPLGEHLGFYCVDVSGHGVGAAMMSLAVARQFLHGRAVERFLFTADNQPASP
AEVVAILNGRFCSDETEIVSYFTLIYGVIDLQTGAGKLCQAGHPTPFIVSPDATVRPVGSGGAPVGLIDHLSWADVSFSL
APGERLCLFSDGITECENRSGEQFGEARLQAWLQDSVTQPLPALLPRFARHLIRWRSGDAQETQAMADDVSLLIIERTGD
SDEN
>Mature_403_residues
SAQHVLIVEDSLVYRRLLSRMLTQWGYIVSEAENGVDALAILENQPVSLVISDWEMPEMNGLTLCREIRRRQFGRYVYLI
LLTAREDPGDLTQGFEAGADDFLSKPVEQSELRARLHAGARILSLEADLAARNTRLSEALRQIEQDLELAARIQQSVLPA
HQLCYQGFFSDWIFLPSAWVSGDIFNVFPLGEHLGFYCVDVSGHGVGAAMMSLAVARQFLHGRAVERFLFTADNQPASPA
EVVAILNGRFCSDETEIVSYFTLIYGVIDLQTGAGKLCQAGHPTPFIVSPDATVRPVGSGGAPVGLIDHLSWADVSFSLA
PGERLCLFSDGITECENRSGEQFGEARLQAWLQDSVTQPLPALLPRFARHLIRWRSGDAQETQAMADDVSLLIIERTGDS
DEN

Specific function: Involved in cross-regulation of inorganic carbon and glucose metabolisms [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1790863, Length=145, Percent_Identity=37.9310344827586, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787229, Length=114, Percent_Identity=41.2280701754386, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787487, Length=207, Percent_Identity=28.9855072463768, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786599, Length=123, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788191, Length=113, Percent_Identity=34.5132743362832, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=38.8349514563107, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=33.0508474576271, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=189, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788905, Length=109, Percent_Identity=40.3669724770642, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=30.5084745762712, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786911, Length=118, Percent_Identity=37.2881355932203, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788394, Length=121, Percent_Identity=33.8842975206612, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003660
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00672 HAMP; PF07228 SpoIIE [H]

EC number: NA

Molecular weight: Translated: 44608; Mature: 44477

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQHVLIVEDSLVYRRLLSRMLTQWGYIVSEAENGVDALAILENQPVSLVISDWEMPEM
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCC
NGLTLCREIRRRQFGRYVYLILLTAREDPGDLTQGFEAGADDFLSKPVEQSELRARLHAG
CCHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHCC
ARILSLEADLAARNTRLSEALRQIEQDLELAARIQQSVLPAHQLCYQGFFSDWIFLPSAW
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHH
VSGDIFNVFPLGEHLGFYCVDVSGHGVGAAMMSLAVARQFLHGRAVERFLFTADNQPASP
CCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
AEVVAILNGRFCSDETEIVSYFTLIYGVIDLQTGAGKLCQAGHPTPFIVSPDATVRPVGS
HHEEHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEECCCCCEEECCC
GGAPVGLIDHLSWADVSFSLAPGERLCLFSDGITECENRSGEQFGEARLQAWLQDSVTQP
CCCCCHHHHCCCCCCCEEEECCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
LPALLPRFARHLIRWRSGDAQETQAMADDVSLLIIERTGDSDEN
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
SAQHVLIVEDSLVYRRLLSRMLTQWGYIVSEAENGVDALAILENQPVSLVISDWEMPEM
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCC
NGLTLCREIRRRQFGRYVYLILLTAREDPGDLTQGFEAGADDFLSKPVEQSELRARLHAG
CCHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHCC
ARILSLEADLAARNTRLSEALRQIEQDLELAARIQQSVLPAHQLCYQGFFSDWIFLPSAW
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHH
VSGDIFNVFPLGEHLGFYCVDVSGHGVGAAMMSLAVARQFLHGRAVERFLFTADNQPASP
CCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
AEVVAILNGRFCSDETEIVSYFTLIYGVIDLQTGAGKLCQAGHPTPFIVSPDATVRPVGS
HHEEHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEECCCCCEEECCC
GGAPVGLIDHLSWADVSFSLAPGERLCLFSDGITECENRSGEQFGEARLQAWLQDSVTQP
CCCCCHHHHCCCCCCCEEEECCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
LPALLPRFARHLIRWRSGDAQETQAMADDVSLLIIERTGDSDEN
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8075401; 8905231 [H]