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The map label for this gene is ttuB [H]

Identifier: 238894312

GI number: 238894312

Start: 2200841

End: 2202151

Strand: Direct

Name: ttuB [H]

Synonym: KP1_2291

Alternate gene names: 238894312

Gene position: 2200841-2202151 (Clockwise)

Preceding gene: 238894310

Following gene: 238894313

Centisome position: 41.93

GC content: 57.21

Gene sequence:

>1311_bases
ATGAAAAACGACCTCGAAAAGAAGGTGATGCGTAAGGTTACCCTGCGCATTATTCCTTTCATCATGCTGCTGTACTTCAT
TGCCTTCCTTGACCGCGTCAACATTGGCTTTGCCGCCCTGACCATGAATCAGGATCTGGGATTTTCACCCACCGTTTTTG
GTCTGGGCGCTGGCATTTTCTTCCTGGGTTATTTTCTGTTTGAGGTACCGTCAAACTTAATTCTTCATAAAGTGGGCGCC
CGCATCTGGATCGCCCGCGTCATGATTACCTGGGGATTCGTCTCTGGCTGCATGGCTTTTGTGCAGGGCACGACGAGCTT
CTACATTCTGCGTTTTCTGCTCGGCGTGGCGGAAGCCGGTTTCTTCCCGGGGATCATTCTCTATCTCAGCTACTGGTTTC
CTGCCGCCAGGCGTGCGCAGGTCACTGCCATCTTTATGGCCGCAGCTCCCCTGTCGACAGCACTGGGATCGCCGGTTTCG
GCCGCACTGCTGGAGATGCATGGCTTCCTTGGCTACGCCGGCTGGCAGTGGATGTTTGTACTGGAAGCTTTGCCGGCGCT
GGTGCTCGGTGTTGTGGTTCTGTTCTTCCTGACGGATCGTCCGGCCAAGGCCAAATGGCTGACTGATCAAGAGCGTGCCT
GGCTGGAAAACGCCATGCAAGACGAGGAGCGGGCACGGGCGGCAAAACAGAGCCATTCCAGCGCATGGCGAGGGCTAGCG
GATATACGCGTCCTGGCGCTGGCGCTGGTCTATTTCGGTACCTCAGCCGGGCTGTATACGCTTGGCATCTGGTCCCCGCA
AATCATTCGCAGTTTCGGTGCTTCCTCGCTGGAGATTGGTTTCCTGAACGCCTTTCCGGCGGTGATCGGCGTCATCGCCA
TGATCCTCTGGGCGCGTCATTCCGATCGAACCAAAGAGCGCAGCTGGCACGTCATTGGCGCCTGCCTGCTGGCGGTTGCC
GGGCTGATATACGCCGGTAATGTCAGCACATTGTTTACCGTAATGGTCGCCTTAACGCTGGTCACCGTGGGGATTAGCGC
ATCAAAACCCCCTTTGTGGAGCATGCCAACCCTGTTCCTCAGCGGCCCGGCTGCGGCCGCTGGCATTGCCGCTATCAACT
CCATCGGCAACCTCGGCGGTTTCGTTGGCCCGATGATGATTGGCGTGATCCGCGAGCAAACCGGTAGCTACAGCTGGGGC
CTGTACTTTGTCGCCGGATTGCTGGCGCTCTCGGCCCTCGTGGTCATGATTCTTTCTGCCAGAGCGAACAAATCGCCGAC
GGCAGAGCTTCCACATCCTCATACTCATTAA

Upstream 100 bases:

>100_bases
TATTTATATAAAGCCGTGCCGATGATAAAGCGGTTCAAAACTTCATACTGGGATTATTACAAAACGATAACAACCCTACA
TCACTATGGAGCATCCCGTC

Downstream 100 bases:

>100_bases
CTGGAGAAGTAACGATGCGTCACTACAAAATTGCTGCCATCCCTGCGGACGGTATCGGACCGGAAGTCATTTCGGCAGGT
ATTGAAGTCTTGCACGCGCT

Product: putative transmembrane transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKNDLEKKVMRKVTLRIIPFIMLLYFIAFLDRVNIGFAALTMNQDLGFSPTVFGLGAGIFFLGYFLFEVPSNLILHKVGA
RIWIARVMITWGFVSGCMAFVQGTTSFYILRFLLGVAEAGFFPGIILYLSYWFPAARRAQVTAIFMAAAPLSTALGSPVS
AALLEMHGFLGYAGWQWMFVLEALPALVLGVVVLFFLTDRPAKAKWLTDQERAWLENAMQDEERARAAKQSHSSAWRGLA
DIRVLALALVYFGTSAGLYTLGIWSPQIIRSFGASSLEIGFLNAFPAVIGVIAMILWARHSDRTKERSWHVIGACLLAVA
GLIYAGNVSTLFTVMVALTLVTVGISASKPPLWSMPTLFLSGPAAAAGIAAINSIGNLGGFVGPMMIGVIREQTGSYSWG
LYFVAGLLALSALVVMILSARANKSPTAELPHPHTH

Sequences:

>Translated_436_residues
MKNDLEKKVMRKVTLRIIPFIMLLYFIAFLDRVNIGFAALTMNQDLGFSPTVFGLGAGIFFLGYFLFEVPSNLILHKVGA
RIWIARVMITWGFVSGCMAFVQGTTSFYILRFLLGVAEAGFFPGIILYLSYWFPAARRAQVTAIFMAAAPLSTALGSPVS
AALLEMHGFLGYAGWQWMFVLEALPALVLGVVVLFFLTDRPAKAKWLTDQERAWLENAMQDEERARAAKQSHSSAWRGLA
DIRVLALALVYFGTSAGLYTLGIWSPQIIRSFGASSLEIGFLNAFPAVIGVIAMILWARHSDRTKERSWHVIGACLLAVA
GLIYAGNVSTLFTVMVALTLVTVGISASKPPLWSMPTLFLSGPAAAAGIAAINSIGNLGGFVGPMMIGVIREQTGSYSWG
LYFVAGLLALSALVVMILSARANKSPTAELPHPHTH
>Mature_436_residues
MKNDLEKKVMRKVTLRIIPFIMLLYFIAFLDRVNIGFAALTMNQDLGFSPTVFGLGAGIFFLGYFLFEVPSNLILHKVGA
RIWIARVMITWGFVSGCMAFVQGTTSFYILRFLLGVAEAGFFPGIILYLSYWFPAARRAQVTAIFMAAAPLSTALGSPVS
AALLEMHGFLGYAGWQWMFVLEALPALVLGVVVLFFLTDRPAKAKWLTDQERAWLENAMQDEERARAAKQSHSSAWRGLA
DIRVLALALVYFGTSAGLYTLGIWSPQIIRSFGASSLEIGFLNAFPAVIGVIAMILWARHSDRTKERSWHVIGACLLAVA
GLIYAGNVSTLFTVMVALTLVTVGISASKPPLWSMPTLFLSGPAAAAGIAAINSIGNLGGFVGPMMIGVIREQTGSYSWG
LYFVAGLLALSALVVMILSARANKSPTAELPHPHTH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=450, Percent_Identity=22.4444444444444, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI9945322, Length=450, Percent_Identity=22, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI6912666, Length=395, Percent_Identity=19.746835443038, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21322234, Length=444, Percent_Identity=20.2702702702703, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082071, Length=430, Percent_Identity=39.3023255813954, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1789152, Length=461, Percent_Identity=24.7288503253796, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=24.7165532879819, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367379, Length=426, Percent_Identity=21.830985915493, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082320, Length=431, Percent_Identity=20.4176334106729, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367193, Length=298, Percent_Identity=22.8187919463087, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=395, Percent_Identity=22.7848101265823, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=395, Percent_Identity=22.7848101265823, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=341, Percent_Identity=23.1671554252199, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86561091, Length=254, Percent_Identity=22.8346456692913, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=320, Percent_Identity=25, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322025, Length=205, Percent_Identity=29.2682926829268, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324410, Length=166, Percent_Identity=27.1084337349398, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=238, Percent_Identity=23.5294117647059, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=303, Percent_Identity=23.4323432343234, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=210, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=214, Percent_Identity=22.4299065420561, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322973, Length=226, Percent_Identity=23.8938053097345, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI45550460, Length=411, Percent_Identity=21.8978102189781, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655255, Length=411, Percent_Identity=21.654501216545, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584153, Length=390, Percent_Identity=22.8205128205128, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639764, Length=465, Percent_Identity=23.6559139784946, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47366; Mature: 47366

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNDLEKKVMRKVTLRIIPFIMLLYFIAFLDRVNIGFAALTMNQDLGFSPTVFGLGAGIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
FLGYFLFEVPSNLILHKVGARIWIARVMITWGFVSGCMAFVQGTTSFYILRFLLGVAEAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
FFPGIILYLSYWFPAARRAQVTAIFMAAAPLSTALGSPVSAALLEMHGFLGYAGWQWMFV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LEALPALVLGVVVLFFLTDRPAKAKWLTDQERAWLENAMQDEERARAAKQSHSSAWRGLA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIRVLALALVYFGTSAGLYTLGIWSPQIIRSFGASSLEIGFLNAFPAVIGVIAMILWARH
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHC
SDRTKERSWHVIGACLLAVAGLIYAGNVSTLFTVMVALTLVTVGISASKPPLWSMPTLFL
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHC
SGPAAAAGIAAINSIGNLGGFVGPMMIGVIREQTGSYSWGLYFVAGLLALSALVVMILSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RANKSPTAELPHPHTH
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNDLEKKVMRKVTLRIIPFIMLLYFIAFLDRVNIGFAALTMNQDLGFSPTVFGLGAGIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
FLGYFLFEVPSNLILHKVGARIWIARVMITWGFVSGCMAFVQGTTSFYILRFLLGVAEAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
FFPGIILYLSYWFPAARRAQVTAIFMAAAPLSTALGSPVSAALLEMHGFLGYAGWQWMFV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LEALPALVLGVVVLFFLTDRPAKAKWLTDQERAWLENAMQDEERARAAKQSHSSAWRGLA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIRVLALALVYFGTSAGLYTLGIWSPQIIRSFGASSLEIGFLNAFPAVIGVIAMILWARH
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHC
SDRTKERSWHVIGACLLAVAGLIYAGNVSTLFTVMVALTLVTVGISASKPPLWSMPTLFL
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHC
SGPAAAAGIAAINSIGNLGGFVGPMMIGVIREQTGSYSWGLYFVAGLLALSALVVMILSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RANKSPTAELPHPHTH
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]