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The map label for this gene is iroN [H]

Identifier: 238894300

GI number: 238894300

Start: 2188602

End: 2190848

Strand: Reverse

Name: iroN [H]

Synonym: KP1_2278

Alternate gene names: 238894300

Gene position: 2190848-2188602 (Counterclockwise)

Preceding gene: 238894301

Following gene: 238894299

Centisome position: 41.74

GC content: 54.52

Gene sequence:

>2247_bases
ATGATAATTGTTATCATTAATATTCTCGATCTCATTTTGTATTGTTTTGAAAAGGATATTTACATGAGATCGCCGCAATA
TTCTGTGCCCACGACCCTGGCGCTGGTTATATCCAGTCTCCTCGCCCCTAACGCCTTTGCTGAAGAATCAGAACAAGATA
CCGAAACGATGATTGTGCGCAGTACGGCGGAAGAGGCGCTTAAGCAACAGCCCGGGGTGTCGATTATCACGGCTGAGGAT
ATTGCTAAGCAGCCGCCGGTCAACGATCTCTCAGACATCATCCGTAAAATGCCCGGGGTGAACTTGACCGGCAACAGCGC
CAGCGGCAGTCGGGGCAACAACCGCCAGATTGATATCCGCGGCATGGGGCCGGAGAACACCCTGATCCTGATAGATGGGG
TACCGGTCACGTCACGTAACGCGGTTCGCTATAGCTGGCGCGGCGAACGCGATACCCGGGGCGACAGCAACTGGGTACCT
GCCGAAATGGTCGAACGGATTGAAGTTCTCCGCGGTCCGGCAGCCGCGCGCTATGGTTCCGGCGCGGCGGGCGGAGTGGT
CAATATCATTACCAAACGTCCGACCAACACCTGGCACGGTTCGCTGTCTTTCTTCTCCAACCAGCCGGAAAACAACAAAG
AAGGCACGACCAATCGCGCTAACTTCAATCTCAGCGGCCCACTGGCCGGCGAGGCGCTGACGATGCGCCTGTATGGCAAT
ATCAATAAAACGGAACCCGACGCCTGGGATATTAACCATGCGCAAAACGGCTCTTACGCTGCGGGGCGCGAAGGGGTCCG
CAATAAAGACATTAACGCGCTACTGTCATGGAAAATGACCCCGCAACAGATCCTCGATTTCAGCTACGCCTATAGCCGTC
AGGGGAATATCTATGCTGGCGATACCCAGTACAGCAACGGCAATCTTAGCCCGAACGGGCTGGTGGACTCCCTGTACGGC
CACGAAACTAATCGCCTCTATCGCCAGTCCTGGGGACTGACCTACAACGGTCTATGGGATTGGGGCCAGTCCAAAGCCGG
TGTTTACTACGAGAAAACCAACAATACCCGCCTGCAGGAAGGCTCTACCGGCCGCGTCGAAGGCATGATCAACAGTGAAG
ATTATGCCACCAGCCGTCTGGAATCCTGGCGTACTACCTCGGAATTCAATGTGCCTTTCTTCTGGCTGGCGGACCAGACG
CTGACGCTGGGAATGGAATGGAACCATGATCAGCTCGACGACCCGGCATCGATGCAGGCCACTAACAGCAACGGCGAGAC
TATCCCTGGGACCTCGGGCGACCCTACGCAACGCAGTACCAAAAACAGCGCCACCCTCACCGGTATCTATCTGGAAGATA
ATATCGAAGCCGTGCCCGGCACCAACCTGATCCCCGGCATTCGCTTCGATTATCATAATCAGTTTGGCAGTAACTGGAGC
CCCAGCCTCAATCTGTCCCAGGAGCTCGGCGATATGTTCACGCTGAAGGCCGGTATCGCGCGCGTGTTTAAAGCGCCAAA
CCTCTATCAATCCAGTAAAGGATATTTGCTCTCCACCCGCGGCAACGGTTGTCCAAACACGATCGCTGAAGGCAGCTGCT
ACCTGCTGGGTAACCCTGACCTCGACCCGGAGATCAGTATCAACAAAGAGATCGGTATCGAATTTAACCTTAATGGTTAC
GCTGCCGGAGTCACCTGGTTTCGCAACGATTACAAAAACAAAATCGTCTCCGGAACAGAGGTACTGGGCTATACCTCCAG
CGGCAATAATATTTTGCAATGGCAGAACGGCGGCAAAGCCGTGGTCGAGGGGCTGGAAGGAAATCTGCTGATCCCGGTGC
TGAGAGATGTCCTCAGCTGGCGGACCAATGCCACCTGGATGCTCAAATCTGAAAGTAAAGAGACTGGCAACCCGCTGTCG
GTTATCCCGAAATATACCGTTAACACGATGCTCGACTGGCAGGTAAACGACGCCCTGTCTGCGAATGTGAACTGGACGCT
TTATGGCCGTCAGAAGCCGCGTCAGTATGCGGAGATCCGCAACGAAACCGGGACCCTTGCCACCACCGAGGTTGGCGCCT
ATTCCATCGTGGGTATTGGTACTCAGTATCAGCTGAACCGGGATATTCGCCTGAATGCCGGAATAAGTAATCTATTTGAT
AAACAACTGTATCGCGAAAATGCCGGCGCCTCGACCTACAATGAGCCTGGCCGCGCGTATTACGCCGGCGTTACCCTCTC
CTTCTGA

Upstream 100 bases:

>100_bases
CCGGCCACACTGTGTAGGCTCTCTTCACGATTTCTCTCAACTGCATAAAAAGTTGCGGTAATTGTGAGGATTTTATGGAG
ATTCATCTCGTTACATTGTA

Downstream 100 bases:

>100_bases
ACCACCGCGCCCGCGCCAGCGGGCGTATTCCCCTATTCTCACTGCGCTATTTTCATAGTAGCATCCCGCTGATCGTCTTT
GACCACAACAGAGTAGAGCA

Product: outer membrane receptor FepA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 748; Mature: 748

Protein sequence:

>748_residues
MIIVIINILDLILYCFEKDIYMRSPQYSVPTTLALVISSLLAPNAFAEESEQDTETMIVRSTAEEALKQQPGVSIITAED
IAKQPPVNDLSDIIRKMPGVNLTGNSASGSRGNNRQIDIRGMGPENTLILIDGVPVTSRNAVRYSWRGERDTRGDSNWVP
AEMVERIEVLRGPAAARYGSGAAGGVVNIITKRPTNTWHGSLSFFSNQPENNKEGTTNRANFNLSGPLAGEALTMRLYGN
INKTEPDAWDINHAQNGSYAAGREGVRNKDINALLSWKMTPQQILDFSYAYSRQGNIYAGDTQYSNGNLSPNGLVDSLYG
HETNRLYRQSWGLTYNGLWDWGQSKAGVYYEKTNNTRLQEGSTGRVEGMINSEDYATSRLESWRTTSEFNVPFFWLADQT
LTLGMEWNHDQLDDPASMQATNSNGETIPGTSGDPTQRSTKNSATLTGIYLEDNIEAVPGTNLIPGIRFDYHNQFGSNWS
PSLNLSQELGDMFTLKAGIARVFKAPNLYQSSKGYLLSTRGNGCPNTIAEGSCYLLGNPDLDPEISINKEIGIEFNLNGY
AAGVTWFRNDYKNKIVSGTEVLGYTSSGNNILQWQNGGKAVVEGLEGNLLIPVLRDVLSWRTNATWMLKSESKETGNPLS
VIPKYTVNTMLDWQVNDALSANVNWTLYGRQKPRQYAEIRNETGTLATTEVGAYSIVGIGTQYQLNRDIRLNAGISNLFD
KQLYRENAGASTYNEPGRAYYAGVTLSF

Sequences:

>Translated_748_residues
MIIVIINILDLILYCFEKDIYMRSPQYSVPTTLALVISSLLAPNAFAEESEQDTETMIVRSTAEEALKQQPGVSIITAED
IAKQPPVNDLSDIIRKMPGVNLTGNSASGSRGNNRQIDIRGMGPENTLILIDGVPVTSRNAVRYSWRGERDTRGDSNWVP
AEMVERIEVLRGPAAARYGSGAAGGVVNIITKRPTNTWHGSLSFFSNQPENNKEGTTNRANFNLSGPLAGEALTMRLYGN
INKTEPDAWDINHAQNGSYAAGREGVRNKDINALLSWKMTPQQILDFSYAYSRQGNIYAGDTQYSNGNLSPNGLVDSLYG
HETNRLYRQSWGLTYNGLWDWGQSKAGVYYEKTNNTRLQEGSTGRVEGMINSEDYATSRLESWRTTSEFNVPFFWLADQT
LTLGMEWNHDQLDDPASMQATNSNGETIPGTSGDPTQRSTKNSATLTGIYLEDNIEAVPGTNLIPGIRFDYHNQFGSNWS
PSLNLSQELGDMFTLKAGIARVFKAPNLYQSSKGYLLSTRGNGCPNTIAEGSCYLLGNPDLDPEISINKEIGIEFNLNGY
AAGVTWFRNDYKNKIVSGTEVLGYTSSGNNILQWQNGGKAVVEGLEGNLLIPVLRDVLSWRTNATWMLKSESKETGNPLS
VIPKYTVNTMLDWQVNDALSANVNWTLYGRQKPRQYAEIRNETGTLATTEVGAYSIVGIGTQYQLNRDIRLNAGISNLFD
KQLYRENAGASTYNEPGRAYYAGVTLSF
>Mature_748_residues
MIIVIINILDLILYCFEKDIYMRSPQYSVPTTLALVISSLLAPNAFAEESEQDTETMIVRSTAEEALKQQPGVSIITAED
IAKQPPVNDLSDIIRKMPGVNLTGNSASGSRGNNRQIDIRGMGPENTLILIDGVPVTSRNAVRYSWRGERDTRGDSNWVP
AEMVERIEVLRGPAAARYGSGAAGGVVNIITKRPTNTWHGSLSFFSNQPENNKEGTTNRANFNLSGPLAGEALTMRLYGN
INKTEPDAWDINHAQNGSYAAGREGVRNKDINALLSWKMTPQQILDFSYAYSRQGNIYAGDTQYSNGNLSPNGLVDSLYG
HETNRLYRQSWGLTYNGLWDWGQSKAGVYYEKTNNTRLQEGSTGRVEGMINSEDYATSRLESWRTTSEFNVPFFWLADQT
LTLGMEWNHDQLDDPASMQATNSNGETIPGTSGDPTQRSTKNSATLTGIYLEDNIEAVPGTNLIPGIRFDYHNQFGSNWS
PSLNLSQELGDMFTLKAGIARVFKAPNLYQSSKGYLLSTRGNGCPNTIAEGSCYLLGNPDLDPEISINKEIGIEFNLNGY
AAGVTWFRNDYKNKIVSGTEVLGYTSSGNNILQWQNGGKAVVEGLEGNLLIPVLRDVLSWRTNATWMLKSESKETGNPLS
VIPKYTVNTMLDWQVNDALSANVNWTLYGRQKPRQYAEIRNETGTLATTEVGAYSIVGIGTQYQLNRDIRLNAGISNLFD
KQLYRENAGASTYNEPGRAYYAGVTLSF

Specific function: Specific receptor for the siderophore ferric enterobactin [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=755, Percent_Identity=50.9933774834437, Blast_Score=698, Evalue=0.0,
Organism=Escherichia coli, GI1788478, Length=727, Percent_Identity=32.8748280605227, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI1790405, Length=731, Percent_Identity=25.1709986320109, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82639; Mature: 82639

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00449 ATPASE_A ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVIINILDLILYCFEKDIYMRSPQYSVPTTLALVISSLLAPNAFAEESEQDTETMIVR
CEEEEEHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCEEEEE
STAEEALKQQPGVSIITAEDIAKQPPVNDLSDIIRKMPGVNLTGNSASGSRGNNRQIDIR
HHHHHHHHHCCCCEEEEHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEE
GMGPENTLILIDGVPVTSRNAVRYSWRGERDTRGDSNWVPAEMVERIEVLRGPAAARYGS
ECCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCC
GAAGGVVNIITKRPTNTWHGSLSFFSNQPENNKEGTTNRANFNLSGPLAGEALTMRLYGN
CCCCCEEEEEECCCCCCCCCEEHEECCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECC
INKTEPDAWDINHAQNGSYAAGREGVRNKDINALLSWKMTPQQILDFSYAYSRQGNIYAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEC
DTQYSNGNLSPNGLVDSLYGHETNRLYRQSWGLTYNGLWDWGQSKAGVYYEKTNNTRLQE
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCEECCEECCCCCCCCEEEEECCCCEECC
GSTGRVEGMINSEDYATSRLESWRTTSEFNVPFFWLADQTLTLGMEWNHDQLDDPASMQA
CCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCEEE
TNSNGETIPGTSGDPTQRSTKNSATLTGIYLEDNIEAVPGTNLIPGIRFDYHNQFGSNWS
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCC
PSLNLSQELGDMFTLKAGIARVFKAPNLYQSSKGYLLSTRGNGCPNTIAEGSCYLLGNPD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCCCCCCCEEEEECCCC
LDPEISINKEIGIEFNLNGYAAGVTWFRNDYKNKIVSGTEVLGYTSSGNNILQWQNGGKA
CCCCEEECCEECEEEECCCEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCHH
VVEGLEGNLLIPVLRDVLSWRTNATWMLKSESKETGNPLSVIPKYTVNTMLDWQVNDALS
EEECCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCEEECEEEEEEECCCEE
ANVNWTLYGRQKPRQYAEIRNETGTLATTEVGAYSIVGIGTQYQLNRDIRLNAGISNLFD
CCEEEEEECCCCCHHHHHHHCCCCCEEEECCCCEEEEECCCEEEECCCEEEECCHHHHHH
KQLYRENAGASTYNEPGRAYYAGVTLSF
HHHHHHCCCCCCCCCCCCEEEEEEEEEC
>Mature Secondary Structure
MIIVIINILDLILYCFEKDIYMRSPQYSVPTTLALVISSLLAPNAFAEESEQDTETMIVR
CEEEEEHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCEEEEE
STAEEALKQQPGVSIITAEDIAKQPPVNDLSDIIRKMPGVNLTGNSASGSRGNNRQIDIR
HHHHHHHHHCCCCEEEEHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEE
GMGPENTLILIDGVPVTSRNAVRYSWRGERDTRGDSNWVPAEMVERIEVLRGPAAARYGS
ECCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCC
GAAGGVVNIITKRPTNTWHGSLSFFSNQPENNKEGTTNRANFNLSGPLAGEALTMRLYGN
CCCCCEEEEEECCCCCCCCCEEHEECCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECC
INKTEPDAWDINHAQNGSYAAGREGVRNKDINALLSWKMTPQQILDFSYAYSRQGNIYAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEC
DTQYSNGNLSPNGLVDSLYGHETNRLYRQSWGLTYNGLWDWGQSKAGVYYEKTNNTRLQE
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCEECCEECCCCCCCCEEEEECCCCEECC
GSTGRVEGMINSEDYATSRLESWRTTSEFNVPFFWLADQTLTLGMEWNHDQLDDPASMQA
CCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCEEE
TNSNGETIPGTSGDPTQRSTKNSATLTGIYLEDNIEAVPGTNLIPGIRFDYHNQFGSNWS
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCC
PSLNLSQELGDMFTLKAGIARVFKAPNLYQSSKGYLLSTRGNGCPNTIAEGSCYLLGNPD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCCCCCCCEEEEECCCC
LDPEISINKEIGIEFNLNGYAAGVTWFRNDYKNKIVSGTEVLGYTSSGNNILQWQNGGKA
CCCCEEECCEECEEEECCCEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCHH
VVEGLEGNLLIPVLRDVLSWRTNATWMLKSESKETGNPLSVIPKYTVNTMLDWQVNDALS
EEECCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCEEECEEEEEEECCCEE
ANVNWTLYGRQKPRQYAEIRNETGTLATTEVGAYSIVGIGTQYQLNRDIRLNAGISNLFD
CCEEEEEECCCCCHHHHHHHCCCCCEEEECCCCEEEEECCCEEEECCCEEEECCHHHHHH
KQLYRENAGASTYNEPGRAYYAGVTLSF
HHHHHHCCCCCCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419284; 10984043 [H]