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The map label for this gene is katE [H]

Identifier: 238894292

GI number: 238894292

Start: 2181522

End: 2183057

Strand: Reverse

Name: katE [H]

Synonym: KP1_2270

Alternate gene names: 238894292

Gene position: 2183057-2181522 (Counterclockwise)

Preceding gene: 238894294

Following gene: 238894291

Centisome position: 41.59

GC content: 59.77

Gene sequence:

>1536_bases
ATGTCTGATAAGCACCCGAACCCTCACCAACAGCAGGCACCGGTCCACGACAGCGAGGAAGCGCAGCCGGGTCTCGATTC
GCTGGCGCCGGACGATCGGGAGTGGCGCCCCACGCCGAAACCTACCGCTCCGGGCGTCGAACCCACCGCCCCAGGCAGCC
TGAAAGCGCCCGATACTCATAACAGCAAACTGGATTCCCTGGAGGCGCAACGCAAAGGGGGGGAAGATTTTCCGCTGACC
ACCAACCAGGGCGTGCGCATTGCTGACGATCAGAATTCGCTGCGCGCCGGTAGCCGCGGCCCAACGCTGCTGGAAGATTT
TATCCTGCGGGAGAAGATCACCCACTTTGACCACGAGCGTATTCCGGAGCGTATCGTTCATGCCCGCGGCTCTGCCGCCC
ACGGCTACTTCCAGCCCTACAAAAGCCTGGCTGCGTTGACTAAAGCCGATTTTCTTTCGTCAGCCGATAAAATCACCCCG
GTGTTTGTACGCTTTTCCACCGTGCAGGGCGGCGCGGGGTCGGCGGACACCGTCCGTGATATTCGCGGCTTCGCTACCAA
GTTTTACACTGACGAAGGGATTTTTGACCTGGTGGGCAACAACACACCGGTCTTCTTCATCCAGGACGCGATGAAGTTCC
CCGACTTTGTCCACGCCGTGAAGCCTGAACCCCACTGGGCCATCCCACAAGGGCAGAGCGCCCACGATACTTTCTGGGAC
TATGTTTCCCTGCAGCCGGAAACGCTGCACAACGTGATGTGGGCGATGTCGGATCGCGGCATCCCGCGCAGCTATCGCAC
CATGGAAGGCTTCGGGATCCACACCTTCCGTCTGATTAATGCCGAGGGCAAAGCCACCTTCGTTCGCTTTCACTGGAAAC
CGGTCGCCGGCAAGGCCTCGCTGGTGTGGGATGAAGCGCAGAAGCTGACCGGCCGCGACCCCGATTTTCATCGCCGCGAT
CTATGGGAGGCCATCGAAGCCGGGGACTACCCGGAATTTGAGCTTGGCCTGCAATTGATCCCCGAAGAGAATGAATTTGC
TTTTGACTTCGACCTGCTCGATCCCACCAAGCTGATCCCCGAGGCGCTGGTGCCGGTGCAGCGGGTTGGCAGAATGGTCC
TCAACCGCAACCCGGATAACTTCTTTGCCGAAAATGAACAGGCGGCCTTCCATCCCGGACATATCGTCCCGGGCATTGAT
TTCAGCAACGATCCGCTGCTGCAGGGGCGTCTCTTCTCTTACACCGATACGCAAATTAGCCGCCTGGGTGGGCCGAACTT
CCATGAAATCCCCATCAACCGTCCGACCTGCCGTATCATAATTTCCAGCGTGACGGGATGCACCGGATGGACATTGACAC
CAATCCGGCCAACTACGAGCCCAACTCGATTAACGACAACTGGCCGCGCGAGACGCCGCCTGCCGCCAAACGCGGTGGCT
TTGAGTCCCTCGCCGAGCGCGTCGACGGCGAAAAAATCCGCCAGCGCAGCCCTTCGTTCGGCGAATATTACGCCCAGCCG
CGTCTGTTCTGGCTGA

Upstream 100 bases:

>100_bases
CCCTGCCCCCTCGCCGGGCGCAGACAGCGTAATGTTCTATAGTTAGAAGGGTTTTGGTCTATCAACGACCACTTTTAGCA
ATGAAAGCAGGAGACGAGTA

Downstream 100 bases:

>100_bases
GCCAGACGCCGATTGAACAGCATCATATTATCGATGGTTTCAGCTTCGAACTCAGCAAAGTGGTCCGCACCTGGATCCGC
GAGCGGGTGGTCGACCATCT

Product: RpoS-dependent hydroperoxidase II

Products: NA

Alternate protein names: Hydroxyperoxidase II [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSDKHPNPHQQQAPVHDSEEAQPGLDSLAPDDREWRPTPKPTAPGVEPTAPGSLKAPDTHNSKLDSLEAQRKGGEDFPLT
TNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLAALTKADFLSSADKITP
VFVRFSTVQGGAGSADTVRDIRGFATKFYTDEGIFDLVGNNTPVFFIQDAMKFPDFVHAVKPEPHWAIPQGQSAHDTFWD
YVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPVAGKASLVWDEAQKLTGRDPDFHRRD
LWEAIEAGDYPEFELGLQLIPEENEFAFDFDLLDPTKLIPEALVPVQRVGRMVLNRNPDNFFAENEQAAFHPGHIVPGID
FSNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCRIIISSVTGCTGWTLTPIRPTTSPTRLTTTGRARRRLPPNAVA
LSPSPSASTAKKSASAALRSANITPSRVCSG

Sequences:

>Translated_511_residues
MSDKHPNPHQQQAPVHDSEEAQPGLDSLAPDDREWRPTPKPTAPGVEPTAPGSLKAPDTHNSKLDSLEAQRKGGEDFPLT
TNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLAALTKADFLSSADKITP
VFVRFSTVQGGAGSADTVRDIRGFATKFYTDEGIFDLVGNNTPVFFIQDAMKFPDFVHAVKPEPHWAIPQGQSAHDTFWD
YVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPVAGKASLVWDEAQKLTGRDPDFHRRD
LWEAIEAGDYPEFELGLQLIPEENEFAFDFDLLDPTKLIPEALVPVQRVGRMVLNRNPDNFFAENEQAAFHPGHIVPGID
FSNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCRIIISSVTGCTGWTLTPIRPTTSPTRLTTTGRARRRLPPNAVA
LSPSPSASTAKKSASAALRSANITPSRVCSG
>Mature_510_residues
SDKHPNPHQQQAPVHDSEEAQPGLDSLAPDDREWRPTPKPTAPGVEPTAPGSLKAPDTHNSKLDSLEAQRKGGEDFPLTT
NQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLAALTKADFLSSADKITPV
FVRFSTVQGGAGSADTVRDIRGFATKFYTDEGIFDLVGNNTPVFFIQDAMKFPDFVHAVKPEPHWAIPQGQSAHDTFWDY
VSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPVAGKASLVWDEAQKLTGRDPDFHRRDL
WEAIEAGDYPEFELGLQLIPEENEFAFDFDLLDPTKLIPEALVPVQRVGRMVLNRNPDNFFAENEQAAFHPGHIVPGIDF
SNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCRIIISSVTGCTGWTLTPIRPTTSPTRLTTTGRARRRLPPNAVAL
SPSPSASTAKKSASAALRSANITPSRVCSG

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=380, Percent_Identity=46.0526315789474, Blast_Score=340, Evalue=2e-93,
Organism=Escherichia coli, GI48994891, Length=431, Percent_Identity=89.5591647331786, Blast_Score=817, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25151141, Length=374, Percent_Identity=48.9304812834225, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71998444, Length=359, Percent_Identity=49.3036211699164, Blast_Score=363, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25147792, Length=359, Percent_Identity=49.3036211699164, Blast_Score=361, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320462, Length=364, Percent_Identity=45.0549450549451, Blast_Score=304, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6321525, Length=337, Percent_Identity=42.7299703264095, Blast_Score=280, Evalue=4e-76,
Organism=Drosophila melanogaster, GI17981717, Length=359, Percent_Identity=46.2395543175487, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI19920968, Length=359, Percent_Identity=44.5682451253482, Blast_Score=322, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 56663; Mature: 56532

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKHPNPHQQQAPVHDSEEAQPGLDSLAPDDREWRPTPKPTAPGVEPTAPGSLKAPDTH
CCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSKLDSLEAQRKGGEDFPLTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHER
CCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHCCHHH
IPERIVHARGSAAHGYFQPYKSLAALTKADFLSSADKITPVFVRFSTVQGGAGSADTVRD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHH
IRGFATKFYTDEGIFDLVGNNTPVFFIQDAMKFPDFVHAVKPEPHWAIPQGQSAHDTFWD
HHHHHHHHCCCCCCEEECCCCCCEEEECCHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHH
YVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPVAGKAS
HEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEECCCCEEEEEEEEEECCCCCE
LVWDEAQKLTGRDPDFHRRDLWEAIEAGDYPEFELGLQLIPEENEFAFDFDLLDPTKLIP
EEHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEECCCCHHHHHH
EALVPVQRVGRMVLNRNPDNFFAENEQAAFHPGHIVPGIDFSNDPLLQGRLFSYTDTQIS
HHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHH
RLGGPNFHEIPINRPTCRIIISSVTGCTGWTLTPIRPTTSPTRLTTTGRARRRLPPNAVA
HCCCCCCEECCCCCCHHEEEEECCCCCCCCEECCCCCCCCCCEEEECCCHHHCCCCCCEE
LSPSPSASTAKKSASAALRSANITPSRVCSG
ECCCCCHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
SDKHPNPHQQQAPVHDSEEAQPGLDSLAPDDREWRPTPKPTAPGVEPTAPGSLKAPDTH
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSKLDSLEAQRKGGEDFPLTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHER
CCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHCCHHH
IPERIVHARGSAAHGYFQPYKSLAALTKADFLSSADKITPVFVRFSTVQGGAGSADTVRD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHH
IRGFATKFYTDEGIFDLVGNNTPVFFIQDAMKFPDFVHAVKPEPHWAIPQGQSAHDTFWD
HHHHHHHHCCCCCCEEECCCCCCEEEECCHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHH
YVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPVAGKAS
HEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEECCCCEEEEEEEEEECCCCCE
LVWDEAQKLTGRDPDFHRRDLWEAIEAGDYPEFELGLQLIPEENEFAFDFDLLDPTKLIP
EEHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEECCCCHHHHHH
EALVPVQRVGRMVLNRNPDNFFAENEQAAFHPGHIVPGIDFSNDPLLQGRLFSYTDTQIS
HHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHH
RLGGPNFHEIPINRPTCRIIISSVTGCTGWTLTPIRPTTSPTRLTTTGRARRRLPPNAVA
HCCCCCCEECCCCCCHHEEEEECCCCCCCCEECCCCCCCCCCEEEECCCHHHCCCCCCEE
LSPSPSASTAKKSASAALRSANITPSRVCSG
ECCCCCHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987146; 9097039; 9278503; 9144772; 7663946; 10091651; 11455600 [H]