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The map label for this gene is celD [H]

Identifier: 238894288

GI number: 238894288

Start: 2177675

End: 2178514

Strand: Direct

Name: celD [H]

Synonym: KP1_2266

Alternate gene names: 238894288

Gene position: 2177675-2178514 (Clockwise)

Preceding gene: 238894287

Following gene: 238894289

Centisome position: 41.49

GC content: 48.33

Gene sequence:

>840_bases
ATGAGGCAGCCCAGAATGATGACCACCGAGATCAGTACCGCCCGAGAACAACAGCTGTTCAACGGGAAGAACTTTCATGT
GGTCATCTATAACAAAACGGAAAGCGTGAGCGGGCTTCACCAGCATGATTACTACGAATTTACCGTGGTGTTAACCGGGC
GCTATTACCAGGAGATCAATGGCAAACGGGTGCTGCTGGAGCGCGGGGATTTCGTCTTTATCCCGATGGGCTCGCACCAC
CAGAGCTTTTACGAGTTCGGGGCGACGCGCATCCTTAACGTCGGCATCAGCAGACGCTTCTTTGAGAAACACTACCTGCC
GCTGCTGCCGTTTGGTCTGGTGGCTTCGCAAGTCTACGCCGTGCAGAGCGCTTTTCTCGGCTACGTTGAGTCGGTCATCG
CCTCACTCAATTTTCGCGAAACGGAATTTGACGAATTTATCGAGCTGGTCTCCTTTTATGTCATTAACCGTTTACGCCAC
TATCGTGAAGAGCCGGTTGCCGACGTGACGCCGCAATGGTTAAAAAATACCGTGGAAGCCATGCATGATAAGCTGAAATT
CGGTGAAGGCGCTCTCGAAAATATGGTTCGCTTATCCGGAAAAACGCAGGAATATTTAACCCGGGCGACCCAGCGCTATT
ATGGTAAAACGCCGATGCAGATAATTAATGATATCCGTATCAACTTTGCCAAAAAACAGCTGGAAATTACCAATTATTCG
GTGACGGATATTGCGTATGAATCAGGTTACAGCAGCCCGAGCTTGTTTATTAAAACCTTTAAAAAACTGACGTCGTTTAC
GCCGAGCAGTTATCGCAAACATTTGACCAGTATTAATTAA

Upstream 100 bases:

>100_bases
GGTGCATGCCCAGGACCATCTGATGACCTCCATGCTGGCTCGTGAGCTGGTGGCCGAATTGATTGAGCTGCACGAGAAGG
TACAATAGGCCATCGCGACG

Downstream 100 bases:

>100_bases
ACCCGCGCGGCGTTCGCCGCCAGGTTTATACCGAAAATCATTCAAGTTAACTGTCCGCATTGTTGCGGAGAGCGGCCTGC
GTCCAGGCGCAGCGCCTAAG

Product: DNA-binding transcriptional regulator ChbR

Products: NA

Alternate protein names: Chb operon repressor [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRQPRMMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVLLERGDFVFIPMGSHH
QSFYEFGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRH
YREEPVADVTPQWLKNTVEAMHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYS
VTDIAYESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN

Sequences:

>Translated_279_residues
MRQPRMMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVLLERGDFVFIPMGSHH
QSFYEFGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRH
YREEPVADVTPQWLKNTVEAMHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYS
VTDIAYESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN
>Mature_279_residues
MRQPRMMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVLLERGDFVFIPMGSHH
QSFYEFGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRH
YREEPVADVTPQWLKNTVEAMHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYS
VTDIAYESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN

Specific function: Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presen

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788030, Length=279, Percent_Identity=81.7204301075269, Blast_Score=481, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013096
- InterPro:   IPR011051
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF07883 Cupin_2; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 32581; Mature: 32581

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQPRMMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEIN
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHCCCEEEEEEEECHHHHHCC
GKRVLLERGDFVFIPMGSHHQSFYEFGATRILNVGISRRFFEKHYLPLLPFGLVASQVYA
CCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRHYREEPVADVTPQWLKNTVEA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYS
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCC
VTDIAYESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN
HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRQPRMMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEIN
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHCCCEEEEEEEECHHHHHCC
GKRVLLERGDFVFIPMGSHHQSFYEFGATRILNVGISRRFFEKHYLPLLPFGLVASQVYA
CCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRHYREEPVADVTPQWLKNTVEA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYS
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCC
VTDIAYESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN
HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 9405618 [H]