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The map label for this gene is astE [H]

Identifier: 238894280

GI number: 238894280

Start: 2170862

End: 2171827

Strand: Direct

Name: astE [H]

Synonym: KP1_2256

Alternate gene names: 238894280

Gene position: 2170862-2171827 (Clockwise)

Preceding gene: 238894279

Following gene: 238894281

Centisome position: 41.36

GC content: 65.42

Gene sequence:

>966_bases
GTGGAACATTTTCTGGCATTAACCCTGGCGGGGCGTTTGCCCCACCATTTTCACGGCGAGACGGCCCATTTCCGCTGGCA
CTGGCTCGGGGAAGGGATCCTTGAGCTGACGCCGCATGCGCGCTGCGAGCGCGGGCTGGTACTTTCCTGCGCCATTCATG
GCAACGAAACGGCGCCGGTGGAGATAGTCGACCACCTGGTGCAGCGACTGGTCCGGGAGGCGCTCCCGCTGCGCTGGCGG
CTGCTGGTGATCGTCGGCAATCCACCAGCGCTGCGGGCGAATAAGCGCTATCTGCACAGCGATATGAACCGCATGTTTGG
CGAGCGCTGGCGGCAGTTTCCGCTCAGTGAGGAGACGCAGCGGGCGCAGCGGCTGGAGCAGGCGGTGGCCCGCTTTTATC
GCGACCACGATGGTCCGCGCTGGCACCTCGATCTGCATACCGCGATCCGCGGGTCGCTACATCCGCGCTTCGGCGTGCTC
CCGGCCCGCGATACGCCGTGGGAGGAGGATTTTCTTCACTGGCTGGGCGGCGCCGGGCTGGAGGCGCTGGTGTTTCATCG
CCAGCCCGGCGGGACCTTCACCCACTTCAGCTGCGAACGGTTCGCGGCGCTGGCCTGCACCCTTGAGCTGGGCAAAGCGC
TGCCGTTGGGGGAAAACGATCTGACGCAGTTTGCCGCCGTCCAGCGGGCGCTCTCCCGGCTGCTGGTGGGGGATCTGGCC
ATTGCCGACGCCCCAGCGCCGCTGCGCTACCGGGTGGTACAGCAGCTAACCCGCCATAGCGATGATTTCCGCTTGCATAT
GGCGGATCAGACGCTGAACTTCACCCCCTTCGAACCCGGCACGCTGCTGGCGGAGGAGGGCGAGACGCGGTATGTGGTGG
GGCCTGAGACGGAGTATGTTCTGTTTCCTAACCCGACGGTGGCGAAAGGACTGCGCGCCGGCCTGATGCTGGAGAAATTA
TCCTGA

Upstream 100 bases:

>100_bases
CGACCCGCAGCTGCTGCGGGAAGGGCGCGACGCGCTGGATCGGTTGACCCAGATCCTGCAGCTCGGTTCGGTTTATCCAT
TTCAGCAATAAGGGGGCGCG

Downstream 100 bases:

>100_bases
GGGCAAGCCGTCCGCCGGGCGGCCTGCTTTATTGCGCGCGTCTTTTTTCGCCATCTTATTTTTTCGTGCTCCAGTGTAAA
TTTGCAGATTATTCCTGGTA

Product: succinylglutamate desuccinylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MEHFLALTLAGRLPHHFHGETAHFRWHWLGEGILELTPHARCERGLVLSCAIHGNETAPVEIVDHLVQRLVREALPLRWR
LLVIVGNPPALRANKRYLHSDMNRMFGERWRQFPLSEETQRAQRLEQAVARFYRDHDGPRWHLDLHTAIRGSLHPRFGVL
PARDTPWEEDFLHWLGGAGLEALVFHRQPGGTFTHFSCERFAALACTLELGKALPLGENDLTQFAAVQRALSRLLVGDLA
IADAPAPLRYRVVQQLTRHSDDFRLHMADQTLNFTPFEPGTLLAEEGETRYVVGPETEYVLFPNPTVAKGLRAGLMLEKL
S

Sequences:

>Translated_321_residues
MEHFLALTLAGRLPHHFHGETAHFRWHWLGEGILELTPHARCERGLVLSCAIHGNETAPVEIVDHLVQRLVREALPLRWR
LLVIVGNPPALRANKRYLHSDMNRMFGERWRQFPLSEETQRAQRLEQAVARFYRDHDGPRWHLDLHTAIRGSLHPRFGVL
PARDTPWEEDFLHWLGGAGLEALVFHRQPGGTFTHFSCERFAALACTLELGKALPLGENDLTQFAAVQRALSRLLVGDLA
IADAPAPLRYRVVQQLTRHSDDFRLHMADQTLNFTPFEPGTLLAEEGETRYVVGPETEYVLFPNPTVAKGLRAGLMLEKL
S
>Mature_321_residues
MEHFLALTLAGRLPHHFHGETAHFRWHWLGEGILELTPHARCERGLVLSCAIHGNETAPVEIVDHLVQRLVREALPLRWR
LLVIVGNPPALRANKRYLHSDMNRMFGERWRQFPLSEETQRAQRLEQAVARFYRDHDGPRWHLDLHTAIRGSLHPRFGVL
PARDTPWEEDFLHWLGGAGLEALVFHRQPGGTFTHFSCERFAALACTLELGKALPLGENDLTQFAAVQRALSRLLVGDLA
IADAPAPLRYRVVQQLTRHSDDFRLHMADQTLNFTPFEPGTLLAEEGETRYVVGPETEYVLFPNPTVAKGLRAGLMLEKL
S

Specific function: Transforms N(2)-succinylglutamate into succinate and glutamate [H]

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788040, Length=323, Percent_Identity=63.4674922600619, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007036
- InterPro:   IPR016681 [H]

Pfam domain/function: PF04952 AstE_AspA [H]

EC number: =3.5.1.96 [H]

Molecular weight: Translated: 36527; Mature: 36527

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHFLALTLAGRLPHHFHGETAHFRWHWLGEGILELTPHARCERGLVLSCAIHGNETAPV
CCCEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHCCCCHHCCCCEEEEEEEECCCCCHH
EIVDHLVQRLVREALPLRWRLLVIVGNPPALRANKRYLHSDMNRMFGERWRQFPLSEETQ
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
RAQRLEQAVARFYRDHDGPRWHLDLHTAIRGSLHPRFGVLPARDTPWEEDFLHWLGGAGL
HHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
EALVFHRQPGGTFTHFSCERFAALACTLELGKALPLGENDLTQFAAVQRALSRLLVGDLA
EEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IADAPAPLRYRVVQQLTRHSDDFRLHMADQTLNFTPFEPGTLLAEEGETRYVVGPETEYV
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCEE
LFPNPTVAKGLRAGLMLEKLS
ECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHFLALTLAGRLPHHFHGETAHFRWHWLGEGILELTPHARCERGLVLSCAIHGNETAPV
CCCEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHCCCCHHCCCCEEEEEEEECCCCCHH
EIVDHLVQRLVREALPLRWRLLVIVGNPPALRANKRYLHSDMNRMFGERWRQFPLSEETQ
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
RAQRLEQAVARFYRDHDGPRWHLDLHTAIRGSLHPRFGVLPARDTPWEEDFLHWLGGAGL
HHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
EALVFHRQPGGTFTHFSCERFAALACTLELGKALPLGENDLTQFAAVQRALSRLLVGDLA
EEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IADAPAPLRYRVVQQLTRHSDDFRLHMADQTLNFTPFEPGTLLAEEGETRYVVGPETEYV
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCEE
LFPNPTVAKGLRAGLMLEKLS
ECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA