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The map label for this gene is mauR [H]

Identifier: 238894241

GI number: 238894241

Start: 2131385

End: 2132266

Strand: Direct

Name: mauR [H]

Synonym: KP1_2210

Alternate gene names: 238894241

Gene position: 2131385-2132266 (Clockwise)

Preceding gene: 238894239

Following gene: 238894243

Centisome position: 40.61

GC content: 66.21

Gene sequence:

>882_bases
ATGACCGCAGAATTCCACTGGGATGATGCGCGCATATTCCTCGCCATCGCCCGGGCGGGAACGCTGAGCGGCGCCGCCGA
CAAGATGAACATGGGGATTGCCACGCTCTCCCGCCGGCTGGATCGGCTGGAGCAGGCGTTGAACGTTCCGCTCTTCAGCC
GCCATCAGAGCGGCTACCGCCTGACCGACGATGGCGAAGCCCTGCTCGCGCGGGCGGAGGCGCTGGAATACGCTGGCCTG
GCGTTCGGCGAAGCGGCGCAACTGCAGGGGCATGTCGCCGGGGTTGTTCGCCTGGCCACCTCGGATAACCTGGCCACGCA
TTTTATTCTGCCCTCCCTGAAAGGGCTCCTGGACCATTATCCCGAGCTGCGGGTGGAGGTGCTGAGCGGCGTGCAGCCGG
TGAACCTGCACCGTCGGGATGCCGATCTGGCGATCCGCATGGTCAAGCCTGAGGCCGGGCATCTGACGTTAAAGCGGCTG
GGGACGGTGGGGTTTGGCGTCTATGGCGCCGCCGACTGTCTGGTCGGCGCGGACGGCCTGTCGCTGAGCGAGGCGGACTT
TGTGGGGTGGCCGGAAACTCACCAGCACCTGCCGGCCGCCCAATGGATCACGCGCACCCTGCGCGGCCGGCCGTGTAAAG
TCGAAGCCAATACGCTCGTGGCCCAGGTTTCCGCAGTATCCGCGGGACTCGGATTGGGCGTCCTGCCGCACTTTATGGCG
CGGGCCAGCGGCCTGCAGTGCCTGCAGCCGGAGATCGGCGCGGATCAGACCCTCTGGCTGGTGATGCATTCTGACCTGGC
CGGATCCAGACGCGTGCGGGTTCTCGCCGACCATCTCATCGCTCTCTTTGCGGACCATCAAGATCGGCTGGCGATGCCCT
GA

Upstream 100 bases:

>100_bases
ATGGCCTGGTTGTCTCCGCGAATGGCGTGCAGTATCATCCCTGCGAAAATGATAAAAAAGAGCGGAAAACGGAGAGCCGT
TTTCCATATATGGAAAATAG

Downstream 100 bases:

>100_bases
AGGGGCGCGGCTTGGGCGTGTATCGATAAGACTGCCCGAGGCTGACGAGCCACGATTTTTTCCGCGCCAGCTAACAGTGA
TACTCGCCGCGCAATATTCG

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTAEFHWDDARIFLAIARAGTLSGAADKMNMGIATLSRRLDRLEQALNVPLFSRHQSGYRLTDDGEALLARAEALEYAGL
AFGEAAQLQGHVAGVVRLATSDNLATHFILPSLKGLLDHYPELRVEVLSGVQPVNLHRRDADLAIRMVKPEAGHLTLKRL
GTVGFGVYGAADCLVGADGLSLSEADFVGWPETHQHLPAAQWITRTLRGRPCKVEANTLVAQVSAVSAGLGLGVLPHFMA
RASGLQCLQPEIGADQTLWLVMHSDLAGSRRVRVLADHLIALFADHQDRLAMP

Sequences:

>Translated_293_residues
MTAEFHWDDARIFLAIARAGTLSGAADKMNMGIATLSRRLDRLEQALNVPLFSRHQSGYRLTDDGEALLARAEALEYAGL
AFGEAAQLQGHVAGVVRLATSDNLATHFILPSLKGLLDHYPELRVEVLSGVQPVNLHRRDADLAIRMVKPEAGHLTLKRL
GTVGFGVYGAADCLVGADGLSLSEADFVGWPETHQHLPAAQWITRTLRGRPCKVEANTLVAQVSAVSAGLGLGVLPHFMA
RASGLQCLQPEIGADQTLWLVMHSDLAGSRRVRVLADHLIALFADHQDRLAMP
>Mature_292_residues
TAEFHWDDARIFLAIARAGTLSGAADKMNMGIATLSRRLDRLEQALNVPLFSRHQSGYRLTDDGEALLARAEALEYAGLA
FGEAAQLQGHVAGVVRLATSDNLATHFILPSLKGLLDHYPELRVEVLSGVQPVNLHRRDADLAIRMVKPEAGHLTLKRLG
TVGFGVYGAADCLVGADGLSLSEADFVGWPETHQHLPAAQWITRTLRGRPCKVEANTLVAQVSAVSAGLGLGVLPHFMAR
ASGLQCLQPEIGADQTLWLVMHSDLAGSRRVRVLADHLIALFADHQDRLAMP

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=25.8503401360544, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081978, Length=300, Percent_Identity=24.6666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=174, Percent_Identity=25.8620689655172, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31652; Mature: 31521

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEFHWDDARIFLAIARAGTLSGAADKMNMGIATLSRRLDRLEQALNVPLFSRHQSGYR
CCCCEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCE
LTDDGEALLARAEALEYAGLAFGEAAQLQGHVAGVVRLATSDNLATHFILPSLKGLLDHY
ECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHC
PELRVEVLSGVQPVNLHRRDADLAIRMVKPEAGHLTLKRLGTVGFGVYGAADCLVGADGL
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHCCCCCCHHHHHHHHCCCCCC
SLSEADFVGWPETHQHLPAAQWITRTLRGRPCKVEANTLVAQVSAVSAGLGLGVLPHFMA
CCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHH
RASGLQCLQPEIGADQTLWLVMHSDLAGSRRVRVLADHLIALFADHQDRLAMP
HHCCCEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TAEFHWDDARIFLAIARAGTLSGAADKMNMGIATLSRRLDRLEQALNVPLFSRHQSGYR
CCCEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCE
LTDDGEALLARAEALEYAGLAFGEAAQLQGHVAGVVRLATSDNLATHFILPSLKGLLDHY
ECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHC
PELRVEVLSGVQPVNLHRRDADLAIRMVKPEAGHLTLKRLGTVGFGVYGAADCLVGADGL
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHCCCCCCHHHHHHHHCCCCCC
SLSEADFVGWPETHQHLPAAQWITRTLRGRPCKVEANTLVAQVSAVSAGLGLGVLPHFMA
CCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHH
RASGLQCLQPEIGADQTLWLVMHSDLAGSRRVRVLADHLIALFADHQDRLAMP
HHCCCEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]