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The map label for this gene is umuD [H]

Identifier: 238894236

GI number: 238894236

Start: 2126480

End: 2126899

Strand: Direct

Name: umuD [H]

Synonym: KP1_2205

Alternate gene names: 238894236

Gene position: 2126480-2126899 (Clockwise)

Preceding gene: 238894234

Following gene: 238894237

Centisome position: 40.52

GC content: 58.1

Gene sequence:

>420_bases
ATGAACGTTTACACGCCGGTTGAGCTACGTCAGATTGTCTCCTTTCCCTTTTTTGCCGACCTGGTGCAGTGCGGCTTTCC
CAGCCCGGCTCAGGACTATGTTGAAAAGCGAATCGACCTCAACGAGCTGCTGGTGCAGCATCCCAGCGCGACCTATTTTG
TCAAAGCCGCTGGCGACAGCATGATCGATGCCGGCATTGACGAAGGCGATCTGCTGGTGGTGGACAGCGCGCGTAAAGCG
GAGCATGGCGATATCGTGATTGCCGCCGTCGGCGGCGAGTTTACGGTAAAGAAGCTGCAGCTTCTGCCGCGGGTGCAGCT
TAATCCGATGAACCCGGCCTATTCGCCCATCGTGGTCGGCCGCGAGGAGACGCTCGATATTTTCGGCGTCGTAACCTACA
TCATCAAGGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
GTTATTTCAGTGCTGGCGATTGATAGCTGGAGCCGATATTGACCGGTAAAACTGGCAAAACTACTGTATATATATTCAGT
ATTGTGTGGTGGGTTGAAAA

Downstream 100 bases:

>100_bases
TCATGTTCGCGCATTGTGATGTGAACGCCTTCTATGCCAGCTGTCAGACCGCCTTCCGGCCAGACCTGAAGGGGCGGCCG
GTGGTGGTGCTGTCGAACAA

Product: DNA polymerase V subunit UmuD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MNVYTPVELRQIVSFPFFADLVQCGFPSPAQDYVEKRIDLNELLVQHPSATYFVKAAGDSMIDAGIDEGDLLVVDSARKA
EHGDIVIAAVGGEFTVKKLQLLPRVQLNPMNPAYSPIVVGREETLDIFGVVTYIIKAAG

Sequences:

>Translated_139_residues
MNVYTPVELRQIVSFPFFADLVQCGFPSPAQDYVEKRIDLNELLVQHPSATYFVKAAGDSMIDAGIDEGDLLVVDSARKA
EHGDIVIAAVGGEFTVKKLQLLPRVQLNPMNPAYSPIVVGREETLDIFGVVTYIIKAAG
>Mature_139_residues
MNVYTPVELRQIVSFPFFADLVQCGFPSPAQDYVEKRIDLNELLVQHPSATYFVKAAGDSMIDAGIDEGDLLVVDSARKA
EHGDIVIAAVGGEFTVKKLQLLPRVQLNPMNPAYSPIVVGREETLDIFGVVTYIIKAAG

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=132, Percent_Identity=75, Blast_Score=213, Evalue=5e-57,
Organism=Escherichia coli, GI1790476, Length=117, Percent_Identity=34.1880341880342, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15166; Mature: 15166

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVYTPVELRQIVSFPFFADLVQCGFPSPAQDYVEKRIDLNELLVQHPSATYFVKAAGDS
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCEEEEEECCCC
MIDAGIDEGDLLVVDSARKAEHGDIVIAAVGGEFTVKKLQLLPRVQLNPMNPAYSPIVVG
HHCCCCCCCCEEEEECCCCCCCCCEEEEEECCCEEHHHHHHCCCCCCCCCCCCCCCEEEC
REETLDIFGVVTYIIKAAG
CHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVYTPVELRQIVSFPFFADLVQCGFPSPAQDYVEKRIDLNELLVQHPSATYFVKAAGDS
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCEEEEEECCCC
MIDAGIDEGDLLVVDSARKAEHGDIVIAAVGGEFTVKKLQLLPRVQLNPMNPAYSPIVVG
HHCCCCCCCCEEEEECCCCCCCCCEEEEEECCCEEHHHHHHCCCCCCCCCCCCCCCEEEC
REETLDIFGVVTYIIKAAG
CHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]