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The map label for this gene is talA [H]

Identifier: 238894163

GI number: 238894163

Start: 2064452

End: 2065402

Strand: Direct

Name: talA [H]

Synonym: KP1_2122

Alternate gene names: 238894163

Gene position: 2064452-2065402 (Clockwise)

Preceding gene: 238894162

Following gene: 238894164

Centisome position: 39.33

GC content: 58.15

Gene sequence:

>951_bases
ATGAGCCAGTTAGACGAACTGAAAAAATACACCACGGTTGTTGCTGATACCGGCGATATTGAATCGATTAAAAAGTTTGC
ACCCCAGGATGCGACCACCAACCCCTCGCTGGTGCTGAAGGCCGCGCAGCTGCCGCAGTATCAGCCGCTGATTGCCGATG
CGATTGGCAAGGCACGCCGCCAGGGAGGCAGCGCAGAAACGCAATTGATTAACGCCTGCGATCAGGTGGCAGTGGATATC
GGCAGCGAGGTGCTGCGCCATGTGCCCGGGCGTATCTCCACCGAAGTGGATGCCCGCTTTGCCTGGGATCGCGGGATGTG
CGTCGCGAAGGCGCGCAAGCTCATCCAGTTATATGAGAAAAATGGCATTGGTCCCGAGCGGATTCTAATTAAGCTCGCCG
CCACCTGGGAGGGCATTCGCGCTGCCGAAGAGTTGGAGCAGAGCGGTATAAACTGCAACCTGACGCTGCTGTTCTCTTTC
GCTCAGGCCCGGGCGTGCGCCGAAGCGGGCGTCTTTCTCATCTCGCCCTTTGTGGGCCGCATCTACGACTGGTATCAGAA
GCACCAGCCGCAGTCAGCCTATCAGGTGGACAGCGATCCGGGCGTGGTCTCTGTGCGCCTGATTTATCAGTATTACAAAT
CTCATGGCTATGACACGGTGGTAATGGGTGCCAGCTTCCGTCGTATTGAGCAGATCCAGGCGCTGGCGGGCTGCGATCGC
CTGACTATCTCTCCGGCACTGCTGGACGAGCTGGCGGCCAGCGAAGGAGTGTTGACCCGCCAGTTGACCCCCGGCTGCGT
GACGGAAACCCGTCCCAGCCCGATGACGCAGGCGGAGTTCCTCTGGCAGCATCATCAGGATCCCATGGCAGTGGAAAAAC
TAGCGGAAGGGATCCGACTGTTTGCTGTCGATCAGGTGAAACTGGAACAACAGATTCAGCAGATGCTGTAA

Upstream 100 bases:

>100_bases
TGAGGGCGGCGGATCCGCGCCCAAAGTGGAACGTATTGATTATTACGAACACCAGCATGCCAGAGATTAATCTCCGCAGT
CGTAAGATAAGGAACAGATG

Downstream 100 bases:

>100_bases
GCCGCAGGGATAAAGACTGATGAAAACGACAAATACCACTCGCCGCCAATGCGCCAACGCGCTGCGCGCCCTGAGCATGG
ACGCTGTACAGAAAGCCAAA

Product: transaldolase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARRQGGSAETQLINACDQVAVDI
GSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEKNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFSF
AQARACAEAGVFLISPFVGRIYDWYQKHQPQSAYQVDSDPGVVSVRLIYQYYKSHGYDTVVMGASFRRIEQIQALAGCDR
LTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRLFAVDQVKLEQQIQQML

Sequences:

>Translated_316_residues
MSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARRQGGSAETQLINACDQVAVDI
GSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEKNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFSF
AQARACAEAGVFLISPFVGRIYDWYQKHQPQSAYQVDSDPGVVSVRLIYQYYKSHGYDTVVMGASFRRIEQIQALAGCDR
LTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRLFAVDQVKLEQQIQQML
>Mature_315_residues
SQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARRQGGSAETQLINACDQVAVDIG
SEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEKNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFSFA
QARACAEAGVFLISPFVGRIYDWYQKHQPQSAYQVDSDPGVVSVRLIYQYYKSHGYDTVVMGASFRRIEQIQALAGCDRL
TISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRLFAVDQVKLEQQIQQML

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway [H]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803187, Length=318, Percent_Identity=55.0314465408805, Blast_Score=355, Evalue=2e-98,
Organism=Escherichia coli, GI1788807, Length=309, Percent_Identity=65.3721682847896, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1786189, Length=314, Percent_Identity=63.6942675159236, Blast_Score=422, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI25153750, Length=321, Percent_Identity=50.7788161993769, Blast_Score=312, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI25153752, Length=167, Percent_Identity=50.8982035928144, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17570473, Length=94, Percent_Identity=47.8723404255319, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323386, Length=319, Percent_Identity=52.0376175548589, Blast_Score=299, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6321480, Length=321, Percent_Identity=46.417445482866, Blast_Score=295, Evalue=9e-81,
Organism=Drosophila melanogaster, GI45549185, Length=319, Percent_Identity=54.858934169279, Blast_Score=345, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225 [H]

Pfam domain/function: PF00923 Transaldolase [H]

EC number: =2.2.1.2 [H]

Molecular weight: Translated: 35024; Mature: 34893

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS01054 TRANSALDOLASE_1 ; PS00958 TRANSALDOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARR
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEHHHCCCCCHHHHHHHHHHHH
QGGSAETQLINACDQVAVDIGSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHH
NGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFSFAQARACAEAGVFLISPFVGR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYDWYQKHQPQSAYQVDSDPGVVSVRLIYQYYKSHGYDTVVMGASFRRIEQIQALAGCDR
HHHHHHHCCCCCCEECCCCCCEEHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCC
LTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRL
EEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEE
FAVDQVKLEQQIQQML
EEHHHHHHHHHHHHHC
>Mature Secondary Structure 
SQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARR
CHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEHHHCCCCCHHHHHHHHHHHH
QGGSAETQLINACDQVAVDIGSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHH
NGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFSFAQARACAEAGVFLISPFVGR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYDWYQKHQPQSAYQVDSDPGVVSVRLIYQYYKSHGYDTVVMGASFRRIEQIQALAGCDR
HHHHHHHCCCCCCEECCCCCCEEHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCC
LTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRL
EEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEE
FAVDQVKLEQQIQQML
EEHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA