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The map label for this gene is mviN [H]

Identifier: 238894116

GI number: 238894116

Start: 2015060

End: 2016634

Strand: Direct

Name: mviN [H]

Synonym: KP1_2070

Alternate gene names: 238894116

Gene position: 2015060-2016634 (Clockwise)

Preceding gene: 238894115

Following gene: 238894118

Centisome position: 38.39

GC content: 58.98

Gene sequence:

>1575_bases
TTGCGGGCGTTTTACTCCAGGGTTTGGAATAACAGCGTAATGAACCTTTTAAAATCACTGGCGGCAGTCAGTTCGATGAC
CATGTTTTCGCGCGTGCTGGGCTTTGCCCGCGATGCGATTGTGGCGCGTATTTTTGGCGCCGGGATGGCGACCGATGCCT
TTTTTGTCGCCTTCAAACTGCCTAACCTGCTGCGGCGTATTTTTGCCGAAGGCGCCTTCTCACAGGCGTTTGTGCCGATC
CTTGCCGAATATAAAAGCAAGCAGGGCGAAGATGCCACCCGCGTGTTTGTCTCATACGTCTCCGGGCTGCTGACCCTGGC
CCTGGCTATCGTTACCGTTATCGGGATGCTGGCGGCGCCGTGGGTAATCACCATTACTGCGCCCGGCTTTGCCGATACCG
CCGATAAGTTTGCGCTAACCACCCAGCTGCTGCGTATTACCTTTCCCTATATTTTGCTGATCTCCCTGGCTTCGCTGGTG
GGGGCGATCCTCAATACCTGGAACCGCTTCTCGGTGCCGGCCTTTGCGCCGACGTTCCTCAACGTCAGTATGATTGGCTT
TGCGCTGTTTGCCGCGCCGTATTTCCATCCGCCGGTGCTGGCGCTGGCCTGGGCGGTGACGGTCGGCGGCGTGCTGCAGC
TGGCTTACCAGCTGCCGCATCTGAAGAAGATTGGCATGCTGGTCCTGCCGCGAATTAATCTGAAAGATGCCGGCGCGATG
CGGGTGGTGAAGCAGATGGGGCCGGCGATCCTTGGCGTGTCGGTAAGCCAGATCTCCCTTATCATCAATACCATTTTCGC
CTCATTCCTCGTGTCGGGCTCGGTGTCGTGGATGTATTATGCCGACCGCCTGATGGAGTTTCCCTCCGGCGTGCTGGGCG
TGGCGCTCGGCACTATCCTGCTGCCATCGCTGTCAAAAAGCTTCGCCAGCGGTAACCATGACGAGTATTGCCGGCTGATG
GACTGGGGACTGCGTCTCTGTTTTCTGCTGGCGCTGCCGAGCGCGGTGGCGCTGGGGATCCTCGCCAAACCGCTAACCGT
GGCTCTGTTCCAGTACGGCAAATTCAGCGCCTTTGACGCGGCGATGACCCAGCGCGCGCTGGTGGCTTATTCCGTAGGGC
TGATGGGCCTTATCGTGGTGAAAGTGCTGGCGCCGGGCTTCTATTCCCGTCAGGACATCAAGACCCCGGTCAAGATTGCT
ATTATCACCCTGATAATGACCCAGGTAATGAACCTGGCGTTTATCGGCCCGCTGAAGCATGCGGGTCTGTCGCTGTCCAT
CGGCCTGGCGGCCTGCCTGAACGCCGCGCTGCTCTACTGGCAACTGCGTAAACAGAAAATTTTCACCCCGCAGCCGGGCT
GGTTGGCCTTCCTGCTGCGTCTGATTATTGCAGTGCTGGTTATGGCCGCGGCGCTGCTGGGCGTCATGCATCTCATGCCT
GAGTGGTCGCTGGGGACGATGCCGTTCCGTCTGATGCGTTTGCTGGCGGTGGTTATCGCCGGGGTGGTAGCCTATTTCGC
CACGCTGCTGGTGCTGGGCTTCCGCGTGAAAGAGTTTGTCCGTCGCACGGCGTAA

Upstream 100 bases:

>100_bases
ACTGTGGCGCGACGCCATTAGCGAATAATCCATTGTAACAACTGACAGTAGTAATTCATGTTGAACCCGGTAGACTATCG
CCACTTTCCAGCGCCCGCAT

Downstream 100 bases:

>100_bases
GCGGTTGTGTGGGTAGAAAAACCCCGCTTCGCCGCAGGCGAAGCGGGGTTTTTTTATGATGCGCTGCGTTCGGCAGCGAG
GATGCGGGCATTCTCCAGCA

Product: putative virulence factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MRAFYSRVWNNSVMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPI
LAEYKSKQGEDATRVFVSYVSGLLTLALAIVTVIGMLAAPWVITITAPGFADTADKFALTTQLLRITFPYILLISLASLV
GAILNTWNRFSVPAFAPTFLNVSMIGFALFAAPYFHPPVLALAWAVTVGGVLQLAYQLPHLKKIGMLVLPRINLKDAGAM
RVVKQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYCRLM
DWGLRLCFLLALPSAVALGILAKPLTVALFQYGKFSAFDAAMTQRALVAYSVGLMGLIVVKVLAPGFYSRQDIKTPVKIA
IITLIMTQVMNLAFIGPLKHAGLSLSIGLAACLNAALLYWQLRKQKIFTPQPGWLAFLLRLIIAVLVMAAALLGVMHLMP
EWSLGTMPFRLMRLLAVVIAGVVAYFATLLVLGFRVKEFVRRTA

Sequences:

>Translated_524_residues
MRAFYSRVWNNSVMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPI
LAEYKSKQGEDATRVFVSYVSGLLTLALAIVTVIGMLAAPWVITITAPGFADTADKFALTTQLLRITFPYILLISLASLV
GAILNTWNRFSVPAFAPTFLNVSMIGFALFAAPYFHPPVLALAWAVTVGGVLQLAYQLPHLKKIGMLVLPRINLKDAGAM
RVVKQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYCRLM
DWGLRLCFLLALPSAVALGILAKPLTVALFQYGKFSAFDAAMTQRALVAYSVGLMGLIVVKVLAPGFYSRQDIKTPVKIA
IITLIMTQVMNLAFIGPLKHAGLSLSIGLAACLNAALLYWQLRKQKIFTPQPGWLAFLLRLIIAVLVMAAALLGVMHLMP
EWSLGTMPFRLMRLLAVVIAGVVAYFATLLVLGFRVKEFVRRTA
>Mature_524_residues
MRAFYSRVWNNSVMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPI
LAEYKSKQGEDATRVFVSYVSGLLTLALAIVTVIGMLAAPWVITITAPGFADTADKFALTTQLLRITFPYILLISLASLV
GAILNTWNRFSVPAFAPTFLNVSMIGFALFAAPYFHPPVLALAWAVTVGGVLQLAYQLPHLKKIGMLVLPRINLKDAGAM
RVVKQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYCRLM
DWGLRLCFLLALPSAVALGILAKPLTVALFQYGKFSAFDAAMTQRALVAYSVGLMGLIVVKVLAPGFYSRQDIKTPVKIA
IITLIMTQVMNLAFIGPLKHAGLSLSIGLAACLNAALLYWQLRKQKIFTPQPGWLAFLLRLIIAVLVMAAALLGVMHLMP
EWSLGTMPFRLMRLLAVVIAGVVAYFATLLVLGFRVKEFVRRTA

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=510, Percent_Identity=91.1764705882353, Blast_Score=922, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 56967; Mature: 56967

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFYSRVWNNSVMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKL
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
PNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAIVTVIGMLAAP
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WVITITAPGFADTADKFALTTQLLRITFPYILLISLASLVGAILNTWNRFSVPAFAPTFL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
NVSMIGFALFAAPYFHPPVLALAWAVTVGGVLQLAYQLPHLKKIGMLVLPRINLKDAGAM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCHHH
RVVKQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGVALGTIL
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LPSLSKSFASGNHDEYCRLMDWGLRLCFLLALPSAVALGILAKPLTVALFQYGKFSAFDA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AMTQRALVAYSVGLMGLIVVKVLAPGFYSRQDIKTPVKIAIITLIMTQVMNLAFIGPLKH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
AGLSLSIGLAACLNAALLYWQLRKQKIFTPQPGWLAFLLRLIIAVLVMAAALLGVMHLMP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
EWSLGTMPFRLMRLLAVVIAGVVAYFATLLVLGFRVKEFVRRTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAFYSRVWNNSVMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKL
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
PNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAIVTVIGMLAAP
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WVITITAPGFADTADKFALTTQLLRITFPYILLISLASLVGAILNTWNRFSVPAFAPTFL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
NVSMIGFALFAAPYFHPPVLALAWAVTVGGVLQLAYQLPHLKKIGMLVLPRINLKDAGAM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCHHH
RVVKQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGVALGTIL
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LPSLSKSFASGNHDEYCRLMDWGLRLCFLLALPSAVALGILAKPLTVALFQYGKFSAFDA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AMTQRALVAYSVGLMGLIVVKVLAPGFYSRQDIKTPVKIAIITLIMTQVMNLAFIGPLKH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
AGLSLSIGLAACLNAALLYWQLRKQKIFTPQPGWLAFLLRLIIAVLVMAAALLGVMHLMP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
EWSLGTMPFRLMRLLAVVIAGVVAYFATLLVLGFRVKEFVRRTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609 [H]