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The map label for this gene is dmsC [H]

Identifier: 238893957

GI number: 238893957

Start: 1842571

End: 1843434

Strand: Direct

Name: dmsC [H]

Synonym: KP1_1898

Alternate gene names: 238893957

Gene position: 1842571-1843434 (Clockwise)

Preceding gene: 238893956

Following gene: 238893958

Centisome position: 35.11

GC content: 61.81

Gene sequence:

>864_bases
ATGGGAAACGGATGGCATGAATGGCCGCTGATGGTCTTTACGGTCTTCGGCCAGTGCGTCGTAGGCGGCTTTATTGTTCT
GGCGCTGGCGCTGATGACAGGCAAGCTTTCCCGTGAGCAGGAGCAGCGCGTGGTGGGCAGCATGTTCGGCCTGTGGGTAT
TGATGGGGATCGGGTTTATTGCCTCGACGATGCACCTTGGCTCGCCGCTGCGGGCCTTTAATTCGCTGAATCGCGTGGGA
GCCTCGTCGCTGAGTAATGAAATCGCCAGCGGGGCGATCTTCTTCGCCGTCGGCGGAATTGGCTGGCTGCTGGCCGTGTG
CAAAAAGCTGCCTGCCGGCCTGCGGAGCCTGTGGCTGGTGGTGACCATGGTGCTGGGCGTGATTTTCGTGTGGATGATGG
TGCGGGTATACAACACCATCGACACGGTGCCGACCTGGTACACCGTTTGGACGCCGCTGAGCTTCTTCCTGACGCTGTTT
ATCGGCGGTCCACTGCTGGGCTACCTGCTGCTGCGCGTCGCAGGCGTCGATGGTTGGGCGCTGCGCCTGCTGCCGGTGGT
TAGTTTGCTGGCGCTGCTGGTCAGTATTATGGTGGTCGTGATGCAGGGAAGTGAACTTGCCACCATCCGCAGCTCAGTTC
AGCAGGCCTCCGCCCTGGTGCCGGATTACGGGTTGCTTATGGCCTGGCGCGTGGTGCTGCTGGCCCTGGCCCTGGCCTGC
TGGTGCGTGCCGCAGATTCGCGGCCGCAAACCGGCGGTCTCGCTGCTCGGCCTGGCCTTTGTTCTGATACTGGCGGGAGA
GATGATCGGCCGCGGCGTATTCTATGGCCTGCATATGACCGTTGGGATGGCTGTCGCCAGTTAA

Upstream 100 bases:

>100_bases
GCGCACTTTACCCGGCCGAGTATCGTTATCAAACCTAACGCCAATGCCCGGCCGTGTGGCGATACCACCGGTTACCTGGC
GAACCCGAAGGAGGTGTGAG

Downstream 100 bases:

>100_bases
CTACCTCCATCATGCCGGTGCCTAACCACCGGCATGATGAAAACGTGCTGTCGATAGATGAAATTTTTCAACTGAAATTA
ACTTCGGCATTTATTAATAA

Product: anaerobic dimethyl sulfoxide reductase subunit C

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGNGWHEWPLMVFTVFGQCVVGGFIVLALALMTGKLSREQEQRVVGSMFGLWVLMGIGFIASTMHLGSPLRAFNSLNRVG
ASSLSNEIASGAIFFAVGGIGWLLAVCKKLPAGLRSLWLVVTMVLGVIFVWMMVRVYNTIDTVPTWYTVWTPLSFFLTLF
IGGPLLGYLLLRVAGVDGWALRLLPVVSLLALLVSIMVVVMQGSELATIRSSVQQASALVPDYGLLMAWRVVLLALALAC
WCVPQIRGRKPAVSLLGLAFVLILAGEMIGRGVFYGLHMTVGMAVAS

Sequences:

>Translated_287_residues
MGNGWHEWPLMVFTVFGQCVVGGFIVLALALMTGKLSREQEQRVVGSMFGLWVLMGIGFIASTMHLGSPLRAFNSLNRVG
ASSLSNEIASGAIFFAVGGIGWLLAVCKKLPAGLRSLWLVVTMVLGVIFVWMMVRVYNTIDTVPTWYTVWTPLSFFLTLF
IGGPLLGYLLLRVAGVDGWALRLLPVVSLLALLVSIMVVVMQGSELATIRSSVQQASALVPDYGLLMAWRVVLLALALAC
WCVPQIRGRKPAVSLLGLAFVLILAGEMIGRGVFYGLHMTVGMAVAS
>Mature_286_residues
GNGWHEWPLMVFTVFGQCVVGGFIVLALALMTGKLSREQEQRVVGSMFGLWVLMGIGFIASTMHLGSPLRAFNSLNRVGA
SSLSNEIASGAIFFAVGGIGWLLAVCKKLPAGLRSLWLVVTMVLGVIFVWMMVRVYNTIDTVPTWYTVWTPLSFFLTLFI
GGPLLGYLLLRVAGVDGWALRLLPVVSLLALLVSIMVVVMQGSELATIRSSVQQASALVPDYGLLMAWRVVLLALALACW
CVPQIRGRKPAVSLLGLAFVLILAGEMIGRGVFYGLHMTVGMAVAS

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=287, Percent_Identity=77.7003484320557, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1787873, Length=286, Percent_Identity=60.8391608391608, Blast_Score=305, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 30977; Mature: 30846

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNGWHEWPLMVFTVFGQCVVGGFIVLALALMTGKLSREQEQRVVGSMFGLWVLMGIGFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASTMHLGSPLRAFNSLNRVGASSLSNEIASGAIFFAVGGIGWLLAVCKKLPAGLRSLWLV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTMVLGVIFVWMMVRVYNTIDTVPTWYTVWTPLSFFLTLFIGGPLLGYLLLRVAGVDGWA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LRLLPVVSLLALLVSIMVVVMQGSELATIRSSVQQASALVPDYGLLMAWRVVLLALALAC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
WCVPQIRGRKPAVSLLGLAFVLILAGEMIGRGVFYGLHMTVGMAVAS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]