Click here to switch to the map view.

The map label for this gene is bglA [H]

Identifier: 238893873

GI number: 238893873

Start: 1743044

End: 1744447

Strand: Direct

Name: bglA [H]

Synonym: KP1_1806

Alternate gene names: 238893873

Gene position: 1743044-1744447 (Clockwise)

Preceding gene: 238893872

Following gene: 238893874

Centisome position: 33.21

GC content: 55.27

Gene sequence:

>1404_bases
ATGACTAGTCATATACCGAGGCGCAGCATGAAGAACAGACTACCGGCAGATTTTTTATGGGGAAATTCCGTCTCCAGCAT
GCAGACGGAGGGGGCGTGGAACGAGGGTGGCAAGGGGATGTCGGTGTATGATATCCGTCAACCGGCGGAGTTCGCCTCCG
ACTGGAAGGTGGCGACCGACTCTTATCATCGTTATCGGGAAGATTTCGATTTGATGCAGGATCTGGGCATGAACTGCTAC
CGTTTTCAGATCGCCTGGAGCCGGGTGTGCCCTGACGGAGATGGCGAATTCAATGAACAGGGGATTGCCTTCTACCATCA
ATTTATAGATGAACTGATCGCCCGCGGCATTGAGCCGATGATCTGCCTGTACCACTTCGATATGCCGCTGTCGCTGGCGG
AGCGCTACAACGGTTTTACCGACCGCCGGGTGATGGACGCTTTTATCCGCTACGGCCAGAAGATGATCGCCTGCTATGGC
GACAAGGTGAAATATTGGCTCACCTTTAATGAGCAGAATCTGTACCATTCGCCGGAAGCGTTTCTGATTTCCGGCTATCT
GCAGGGGGAGAAGACCCTGCGCGAACTGTATCTGATCCAGCATCATGTGATGATGGCGCACGTCCATCTAACTCACTATC
TGCACCAGACGAAGCCGCAGTGTCTGATGGGCGGAATGCTGGCTCACGCTCTGGTCTATCCGGCTACCTGCAAACCACGC
GATATCCTCTGCGCCCAGCAGCTGGATGAGTTCTTAAACCAGAACCTGCTGCGCGCCTACGCGGGTGAGGGTTATAGCCC
GGAGGTGATGCATTTTGTCGCCGCGGAAGGGTTCGATGATATCTATCGTCCGGAGGATCTCGCCCTGATGGCGACGGTGA
AGGTCGATTATCTGGCGTTCAGCTTTTACGCCAGCCGCACATTGAACAGCGACGCGATCCCGCCGGGAACGGCGGTCAAC
AACTATATGCTGTTTGGCAACCAGGATAACCCGTTCCTGAAAGCGACGGAATGGAACTGGCAGATTGATCCGCTGGGCTT
CCGGACGATCATCACTCGTTACTATAACGACTGGCGCCTGCCGGTGTTCCCGATTGAAAACGGCATCGGGGTGATTGAGT
CCTGGGACGGCGAACATCCCATTGCCGATGATTACCGCATCGCTTACCATCGCGACCATATCAACGCCATGAAAGCGGCC
ATCTTTGAGGATGGGGCGCAGGTGATCGGCTATCTCGGCTGGGGATTAATCGATATCCTGAGCTCACAGGGCGATATGCG
TAAGCGCTACGGCGTGGTGTACGTCAATCGCGAAAACCATGACCTCAAGGACCTGCGGCGGGTGCCGAAGAAGAGCTATG
CATGGCTGAAGCAGGTGTTCCGCAGCAACGGCGAAGCGATGTAA

Upstream 100 bases:

>100_bases
CGCCTTTCGGGGCGATCTTTTTTTGTCCGGCTCACAGAAACCGATCCCGGCCTTTGCTTACCTTTTCACTTTCCGGTATA
TGACTAGTCATTACGTTTAA

Downstream 100 bases:

>100_bases
CGCTGCCCTGGCGGTCAGATGGTGTATCCAGCCCGCCAGCCACTCACTGAATGGATAAGGACCGGGAAATGACGGCGAAG
TATCTGCAAATCGCGCGGGA

Product: putative family 1 glycoside hydrolase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTSHIPRRSMKNRLPADFLWGNSVSSMQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCY
RFQIAWSRVCPDGDGEFNEQGIAFYHQFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYG
DKVKYWLTFNEQNLYHSPEAFLISGYLQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPR
DILCAQQLDEFLNQNLLRAYAGEGYSPEVMHFVAAEGFDDIYRPEDLALMATVKVDYLAFSFYASRTLNSDAIPPGTAVN
NYMLFGNQDNPFLKATEWNWQIDPLGFRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAA
IFEDGAQVIGYLGWGLIDILSSQGDMRKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM

Sequences:

>Translated_467_residues
MTSHIPRRSMKNRLPADFLWGNSVSSMQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCY
RFQIAWSRVCPDGDGEFNEQGIAFYHQFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYG
DKVKYWLTFNEQNLYHSPEAFLISGYLQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPR
DILCAQQLDEFLNQNLLRAYAGEGYSPEVMHFVAAEGFDDIYRPEDLALMATVKVDYLAFSFYASRTLNSDAIPPGTAVN
NYMLFGNQDNPFLKATEWNWQIDPLGFRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAA
IFEDGAQVIGYLGWGLIDILSSQGDMRKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM
>Mature_466_residues
TSHIPRRSMKNRLPADFLWGNSVSSMQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATDSYHRYREDFDLMQDLGMNCYR
FQIAWSRVCPDGDGEFNEQGIAFYHQFIDELIARGIEPMICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYGD
KVKYWLTFNEQNLYHSPEAFLISGYLQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPRD
ILCAQQLDEFLNQNLLRAYAGEGYSPEVMHFVAAEGFDDIYRPEDLALMATVKVDYLAFSFYASRTLNSDAIPPGTAVNN
YMLFGNQDNPFLKATEWNWQIDPLGFRTIITRYYNDWRLPVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAAI
FEDGAQVIGYLGWGLIDILSSQGDMRKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=484, Percent_Identity=27.6859504132231, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI110681710, Length=486, Percent_Identity=29.2181069958848, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI28376633, Length=468, Percent_Identity=27.991452991453, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI13273313, Length=472, Percent_Identity=26.4830508474576, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI24497614, Length=487, Percent_Identity=26.4887063655031, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI2367174, Length=480, Percent_Identity=36.4583333333333, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=36.0995850622407, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI2367270, Length=467, Percent_Identity=36.4025695931477, Blast_Score=296, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17539390, Length=479, Percent_Identity=26.9311064718163, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17552856, Length=476, Percent_Identity=27.3109243697479, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21356577, Length=489, Percent_Identity=25.5623721881391, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54160; Mature: 54029

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSHIPRRSMKNRLPADFLWGNSVSSMQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATD
CCCCCCCHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCHHH
SYHRYREDFDLMQDLGMNCYRFQIAWSRVCPDGDGEFNEQGIAFYHQFIDELIARGIEPM
HHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
ICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYGDKVKYWLTFNEQNLYHSPEA
EEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCHHEEEEECCCEEEEEEECCCCCCCCCCE
FLISGYLQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPR
EEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCH
DILCAQQLDEFLNQNLLRAYAGEGYSPEVMHFVAAEGFDDIYRPEDLALMATVKVDYLAF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCEEEEEEEEHHHHHH
SFYASRTLNSDAIPPGTAVNNYMLFGNQDNPFLKATEWNWQIDPLGFRTIITRYYNDWRL
HHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCEEECCCHHHHHHHHHHCCCCC
PVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAAIFEDGAQVIGYLGWGLIDIL
EEEECCCCCCEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSQGDMRKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM
HCCCCHHHHCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSHIPRRSMKNRLPADFLWGNSVSSMQTEGAWNEGGKGMSVYDIRQPAEFASDWKVATD
CCCCCCHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCHHH
SYHRYREDFDLMQDLGMNCYRFQIAWSRVCPDGDGEFNEQGIAFYHQFIDELIARGIEPM
HHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
ICLYHFDMPLSLAERYNGFTDRRVMDAFIRYGQKMIACYGDKVKYWLTFNEQNLYHSPEA
EEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCHHEEEEECCCEEEEEEECCCCCCCCCCE
FLISGYLQGEKTLRELYLIQHHVMMAHVHLTHYLHQTKPQCLMGGMLAHALVYPATCKPR
EEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCH
DILCAQQLDEFLNQNLLRAYAGEGYSPEVMHFVAAEGFDDIYRPEDLALMATVKVDYLAF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCEEEEEEEEHHHHHH
SFYASRTLNSDAIPPGTAVNNYMLFGNQDNPFLKATEWNWQIDPLGFRTIITRYYNDWRL
HHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCEEECCCHHHHHHHHHHCCCCC
PVFPIENGIGVIESWDGEHPIADDYRIAYHRDHINAMKAAIFEDGAQVIGYLGWGLIDIL
EEEECCCCCCEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSQGDMRKRYGVVYVNRENHDLKDLRRVPKKSYAWLKQVFRSNGEAM
HCCCCHHHHCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]