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The map label for this gene is hutI [H]

Identifier: 238893812

GI number: 238893812

Start: 1682273

End: 1683658

Strand: Direct

Name: hutI [H]

Synonym: KP1_1742

Alternate gene names: 238893812

Gene position: 1682273-1683658 (Clockwise)

Preceding gene: 238893810

Following gene: 238893813

Centisome position: 32.05

GC content: 61.47

Gene sequence:

>1386_bases
TTGAACGAAACGGGAAGACGTGGACGGAAAAACTTACCGTCTTTACGCAACGCGCAGCCCTGCCGGATGGTCTTTAGTCA
CAAAAAAATAACATTTCCCTGCGCTATTGTTGACTTTACCGGCGTTATGAAAATAAATGTCTATACAACCCATGACAAGT
TAAGCGCTATGACTGAAGCCACTTCCGAATTCGTTATCTGGCGAAACGGGCGTCTCGCCACCCTGAACCCCGATCACGCT
CAACCTTACGGCCTGCTGGAGCGCCATGCGCTGCTGGTGCGCGACGGCCGCATCGCGGCGATTGTCGCCGAAGATGACGT
CCCCAGCGGGCGCAGTATCGATCTTGAAGGCCGGTTGGTAACGCCGGGATTAATCGACTGCCACACCCATCTCGTCTTCG
GCGGCAGCCGGGCCCAGGAGTGGGAGCAGCGGCTGAACGGCGTGTCGTATCAAACCATCAGCGCCAGCGGCGGCGGCATT
AACTCCACCGTGCGCGCCACGCGCGACAGCAGCGAAGCTGAACTACTGGCGCTGGCCCAGCCGCGTCTGGAACGCCTGCT
GCGTGAAGGGGTGACCACCCTGGAGATCAAATCCGGCTACGGCCTCGACCTGCCAAACGAACGCAAAATGCTGCGGGTCG
CCCGACAACTGGCCGATCATAATGGCGTGGAACTGTCGGCGACGCTGCTCTCCGCCCACGCCACGCCGCCGGAATATCAA
GGCGATGCTGACGGCTATATTACGCTGGTCTGCGAGACCATTTTGCCGACGCTGTGGCAGGAGGGACTGTTTGAAAGCGT
TGACGTCTTCTGCGAAAACGTCGGCTTCAGCCCGCAGCAAACTGAGCGCGTCTTTCAGGCGGCGCAGGCGCTGGGCATTC
CGGTAAAAGGCCACGTTGAGCAGCTCTCGTCGCTGGGCGGCGCGCAGCTGGTGAGCCGCTATCATGGGCTTTCCGCCGAC
CATATCGAGTATCTGACGGAAGAGGGCGTGGCGGCGATGCGCGAAAGCGGCACCGTGGCAGCCCTGCTCCCCGGCGCGTT
CTACTTCCTTAATGAAACCCGTAAACCGCCGGTCGAGCTGCTGCGCAAGTACCAGGTGCCGATGGCGGTGGCGACCGATT
TCAACCCCGGCACCAGCCCCTTCGCCAGCCTGCATCTGGCGATGAACATGGCCTGCGTCAAGTTTGGCCTGACGCCGGAG
GAGGCGTGGACCGGGGTGACGCGCCATGCCGCACAGGCGCTGGGGCGCCAGGCCAGCCACGGCCAGCTGGCGCCGGGCTT
TGTCGCTAACTTCGCCATCTGGGATGCTGAACATCCCGTCGAGATGGTGTATGAGCCGGGGCGCAGTCCGCTCTGGCATC
GCGTTGTTCAAGGAGAGTTGCAATGA

Upstream 100 bases:

>100_bases
ATATGTGTTCATGTTGCTCCGGGCAAAATTAAGCGTAGTGAAATACCCCGGCTGAGACGCCAGGGTATAAGTCCTTTAAA
ACCTGCTGTTTTATACTAAC

Downstream 100 bases:

>100_bases
TGCTGTGGCAAGCTACGCCAGCCAGTCTCTGGCAGGGACGCGACGACAGCGCGGAAGCGCCCAATGCGCTGCGCCTGTTC
CAGACCATCGCCCGCGCGGA

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MNETGRRGRKNLPSLRNAQPCRMVFSHKKITFPCAIVDFTGVMKINVYTTHDKLSAMTEATSEFVIWRNGRLATLNPDHA
QPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGI
NSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQ
GDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVEQLSSLGGAQLVSRYHGLSAD
HIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPE
EAWTGVTRHAAQALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ

Sequences:

>Translated_461_residues
MNETGRRGRKNLPSLRNAQPCRMVFSHKKITFPCAIVDFTGVMKINVYTTHDKLSAMTEATSEFVIWRNGRLATLNPDHA
QPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGI
NSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQ
GDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVEQLSSLGGAQLVSRYHGLSAD
HIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPE
EAWTGVTRHAAQALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
>Mature_461_residues
MNETGRRGRKNLPSLRNAQPCRMVFSHKKITFPCAIVDFTGVMKINVYTTHDKLSAMTEATSEFVIWRNGRLATLNPDHA
QPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGI
NSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQ
GDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVEQLSSLGGAQLVSRYHGLSAD
HIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPE
EAWTGVTRHAAQALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=388, Percent_Identity=33.7628865979381, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17555004, Length=369, Percent_Identity=33.3333333333333, Blast_Score=201, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 50555; Mature: 50555

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETGRRGRKNLPSLRNAQPCRMVFSHKKITFPCAIVDFTGVMKINVYTTHDKLSAMTEA
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEECCCEEEEEEEECHHHHHHHHHC
TSEFVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLV
CCCEEEEECCEEEECCCCCCCCCHHHHHCEEEEECCCEEEEEECCCCCCCCEEECCCEEE
TPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQ
CCCCEECEEEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCCCCCHHHHHHHH
PRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQ
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCC
GDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVE
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
QLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVEL
HHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHEECCCCCCCHHHH
LRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPEEAWTGVTRHAAQALGRQASH
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
GQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
CCCCCCHHHEEEEECCCCCHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MNETGRRGRKNLPSLRNAQPCRMVFSHKKITFPCAIVDFTGVMKINVYTTHDKLSAMTEA
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEECCCEEEEEEEECHHHHHHHHHC
TSEFVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLV
CCCEEEEECCEEEECCCCCCCCCHHHHHCEEEEECCCEEEEEECCCCCCCCEEECCCEEE
TPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQ
CCCCEECEEEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCCCCCHHHHHHHH
PRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQ
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCC
GDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVE
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
QLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVEL
HHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHEECCCCCCCHHHH
LRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPEEAWTGVTRHAAQALGRQASH
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
GQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
CCCCCCHHHEEEEECCCCCHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA