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The map label for this gene is ybgR [H]

Identifier: 238893781

GI number: 238893781

Start: 1650402

End: 1651346

Strand: Reverse

Name: ybgR [H]

Synonym: KP1_1708

Alternate gene names: 238893781

Gene position: 1651346-1650402 (Counterclockwise)

Preceding gene: 238893782

Following gene: 238893767

Centisome position: 31.46

GC content: 60.85

Gene sequence:

>945_bases
ATGGCGCACTCGCATTCGCACTCCTCTGTCCAGGCTCCGGATAACAGCAACGCCCGCCGGCTGCTATGGGCGTTTATCGT
CACCGCCGGCTTTATGCTGATTGAAGCCGTCGGCGGCGCGATCTCCGGCTCGCTGGCCCTGCTGGCGGATGCCGGCCATA
TGCTCACCGACTCCGCCGCTCTGCTGTTTGCGCTGCTGGCGGTTCGCTTCGCCAGCCGCCCACCAAATGCCCGCCATACC
TTTGGCTGGTTGCGTTTAACCACCCTGGCGGCGTTTCTCAATGCTATTGCTCTGGTGGTGATCACCATGCTGATTGTCTG
GGAGGCGATTCAGCGCTTCCAGCATCCGCAACCGGTAGCCGGCGTGACGATGATGGTCATTGCAGTCGCCGGTCTGCTGG
CCAACGTGCTGGCGTTTTGGATCCTACATCGGGGTAGCGAGGAGCGGAATCTTAACGTACGCGCCGCAGCGCTACACGTG
CTTGGCGACCTGCTGGGCTCGGTCGGCGCGATCGTGGCGGCCGTGGTGATCCTCACCACCGGCTGGACGCCTGTCGACCC
GATTCTTTCCGTGCTGGTTTCCTGCCTGGTATTACGTAGTGCCTGGCGATTACTGAAAGAGAGTCTGAATGAATTGCTGG
AAGGCGCGCCGCGTTCGCTGGATGTGGCGGCCCTGCAGCGGGATATCCGTCGCTCTATCCCGGAGGTACGCGATGTTCAC
CACGTCCACGTCTGGCTGGTGGGGGAAAAACCGGTGATGACGCTCCATGTACAGGTCGTTCCACCGCACGATCATGACGC
GTTACTCAACCGCATCCTGCATTTCCTGGAACATAAATATGAAATTGCGCATGCCACGGTGCAGATGGAGTACCAGCCCT
GCAGCGGCCCGGAGTGCCATCTCAACACGATGCACGCCGGGCACGATCATCACCACCACCATTAG

Upstream 100 bases:

>100_bases
TCGAAGAAAAGGCGAGCCGGTCTCGCCTTTTCTTCGTTTTTTATCGCTCTCTGTTTATGATGTCATAGCGTAATAATGAT
AACTATTAAGGGACGACACT

Downstream 100 bases:

>100_bases
CCAGAAAACGCGTGAGAACCTCGCTCACGCGCGCTATTTATCCACATCCGGCTGCCGTTCAACGCAATGAACGTCAGCAA
GAGGTATTCCAGCGACATGG

Product: zinc transporter ZitB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAHSHSHSSVQAPDNSNARRLLWAFIVTAGFMLIEAVGGAISGSLALLADAGHMLTDSAALLFALLAVRFASRPPNARHT
FGWLRLTTLAAFLNAIALVVITMLIVWEAIQRFQHPQPVAGVTMMVIAVAGLLANVLAFWILHRGSEERNLNVRAAALHV
LGDLLGSVGAIVAAVVILTTGWTPVDPILSVLVSCLVLRSAWRLLKESLNELLEGAPRSLDVAALQRDIRRSIPEVRDVH
HVHVWLVGEKPVMTLHVQVVPPHDHDALLNRILHFLEHKYEIAHATVQMEYQPCSGPECHLNTMHAGHDHHHHH

Sequences:

>Translated_314_residues
MAHSHSHSSVQAPDNSNARRLLWAFIVTAGFMLIEAVGGAISGSLALLADAGHMLTDSAALLFALLAVRFASRPPNARHT
FGWLRLTTLAAFLNAIALVVITMLIVWEAIQRFQHPQPVAGVTMMVIAVAGLLANVLAFWILHRGSEERNLNVRAAALHV
LGDLLGSVGAIVAAVVILTTGWTPVDPILSVLVSCLVLRSAWRLLKESLNELLEGAPRSLDVAALQRDIRRSIPEVRDVH
HVHVWLVGEKPVMTLHVQVVPPHDHDALLNRILHFLEHKYEIAHATVQMEYQPCSGPECHLNTMHAGHDHHHHH
>Mature_313_residues
AHSHSHSSVQAPDNSNARRLLWAFIVTAGFMLIEAVGGAISGSLALLADAGHMLTDSAALLFALLAVRFASRPPNARHTF
GWLRLTTLAAFLNAIALVVITMLIVWEAIQRFQHPQPVAGVTMMVIAVAGLLANVLAFWILHRGSEERNLNVRAAALHVL
GDLLGSVGAIVAAVVILTTGWTPVDPILSVLVSCLVLRSAWRLLKESLNELLEGAPRSLDVAALQRDIRRSIPEVRDVHH
VHVWLVGEKPVMTLHVQVVPPHDHDALLNRILHFLEHKYEIAHATVQMEYQPCSGPECHLNTMHAGHDHHHHH

Specific function: Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=307, Percent_Identity=31.2703583061889, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI289803013, Length=313, Percent_Identity=30.6709265175719, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI289803009, Length=313, Percent_Identity=30.6709265175719, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI289803007, Length=313, Percent_Identity=30.6709265175719, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI289803003, Length=313, Percent_Identity=30.6709265175719, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI64762489, Length=313, Percent_Identity=30.6709265175719, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI21359890, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI21361112, Length=309, Percent_Identity=32.3624595469256, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI14210520, Length=230, Percent_Identity=28.695652173913, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI20070323, Length=328, Percent_Identity=25, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI52352803, Length=132, Percent_Identity=41.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI52351208, Length=160, Percent_Identity=29.375, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786966, Length=295, Percent_Identity=77.2881355932203, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1790349, Length=236, Percent_Identity=27.5423728813559, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193210990, Length=320, Percent_Identity=30.625, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17555794, Length=309, Percent_Identity=32.0388349514563, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17555796, Length=310, Percent_Identity=30.9677419354839, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32564488, Length=309, Percent_Identity=29.4498381877023, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17550440, Length=131, Percent_Identity=32.824427480916, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17550442, Length=131, Percent_Identity=32.824427480916, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323899, Length=126, Percent_Identity=38.8888888888889, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320411, Length=179, Percent_Identity=32.9608938547486, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324892, Length=135, Percent_Identity=34.0740740740741, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24656728, Length=342, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24656724, Length=342, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24656720, Length=342, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24656715, Length=342, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21357035, Length=342, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583858, Length=333, Percent_Identity=26.7267267267267, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24585900, Length=147, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24585898, Length=147, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24585896, Length=147, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI19921672, Length=147, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24584409, Length=136, Percent_Identity=36.0294117647059, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574430, Length=136, Percent_Identity=36.0294117647059, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24645863, Length=126, Percent_Identity=29.3650793650794, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34427; Mature: 34295

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSHSHSSVQAPDNSNARRLLWAFIVTAGFMLIEAVGGAISGSLALLADAGHMLTDSAA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHCCCHHHHHHHH
LLFALLAVRFASRPPNARHTFGWLRLTTLAAFLNAIALVVITMLIVWEAIQRFQHPQPVA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GVTMMVIAVAGLLANVLAFWILHRGSEERNLNVRAAALHVLGDLLGSVGAIVAAVVILTT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWTPVDPILSVLVSCLVLRSAWRLLKESLNELLEGAPRSLDVAALQRDIRRSIPEVRDVH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHCCC
HVHVWLVGEKPVMTLHVQVVPPHDHDALLNRILHFLEHKYEIAHATVQMEYQPCSGPECH
EEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
LNTMHAGHDHHHHH
CCCCCCCCCCCCCC
>Mature Secondary Structure 
AHSHSHSSVQAPDNSNARRLLWAFIVTAGFMLIEAVGGAISGSLALLADAGHMLTDSAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHCCCHHHHHHHH
LLFALLAVRFASRPPNARHTFGWLRLTTLAAFLNAIALVVITMLIVWEAIQRFQHPQPVA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GVTMMVIAVAGLLANVLAFWILHRGSEERNLNVRAAALHVLGDLLGSVGAIVAAVVILTT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWTPVDPILSVLVSCLVLRSAWRLLKESLNELLEGAPRSLDVAALQRDIRRSIPEVRDVH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHCCC
HVHVWLVGEKPVMTLHVQVVPPHDHDALLNRILHFLEHKYEIAHATVQMEYQPCSGPECH
EEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
LNTMHAGHDHHHHH
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]