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The map label for this gene is pgm [H]

Identifier: 238893740

GI number: 238893740

Start: 1605012

End: 1606673

Strand: Direct

Name: pgm [H]

Synonym: KP1_1664

Alternate gene names: 238893740

Gene position: 1605012-1606673 (Clockwise)

Preceding gene: 238893739

Following gene: 238893741

Centisome position: 30.58

GC content: 60.11

Gene sequence:

>1662_bases
TTGCACCAGAAGGATCAGGCAATGGCAATCGATAAACGTGCGGGGCAGCCTGCGCAACAGAGTGATTTGATTAACGTCGC
CCAACTGACTGCTCAGTACTACGTGCTGAAGCCTGAAGTCGGTAATGCGGAGCATGCGGTAAAATTCGGCACCTCTGGCC
ATCGCGGTAGCGCGGCGCGCCACAACTTCAACGAACCGCATATCCTGGCCATCGCCCAGGCCATTGCGGAAGATCGTGCG
AAAAACGGGATCACCGGTCCGTGCTATGTCGGCAAAGATACCCACGCCCTCTCCGAGCCGGCATTTATTTCGGTGCTGGA
AGTGTTAACCGCCAACGGCGTCGACGTGATCGTGCAGGAAAACAACGGCTTCACCCCGACGCCGGCGGTCTCCAACGCGA
TTCTGGTGCATAACAAAAAAGGCGGTCCGCTGGCGGACGGCATTGTGATCACCCCGTCACACAACCCGCCGGAAGATGGT
GGTATCAAGTACAATCCGCCAAACGGCGGCCCGGCTGATACCAACGTCACCAAAGTGGTGGAAAACCGCGCCAACGAACT
GCTGGCCGCGGGCCTGCAGGGCGTGAAACGCATTTCTCTGGACGCGGCGCTGGCTTCTGGCCACGTTAAAGAACAGGATC
TGGTGCAGCCGTTCATCGAAGGGCTGGCGGATATCGTCGATATGGCCGCAATCCAGAAAGCCGGCCTGACGCTGGGCGTC
GATCCGCTGGGCGGGTCCGGTATCGAATACTGGAAACGCATTGGCGAGCACTACAAGCTCAATCTGACCATTGTTAACGA
TCAGGTGGATCAGACCTTCCGCTTTATGCACCTCGATAAAGACGGCGCCATCCGCATGGATTGCTCCTCAGAGTGTGCGA
TGGCCGGCCTGCTGGCGCTGCGCGATAAGTTCGATCTGGCGTTTGCTAACGACCCGGATTACGACCGCCACGGGATTGTC
ACCCCGGCGGGGTTGATGAACCCGAACCACTACCTGGCGGTAGCGATCAACTACCTGTTCCAGCATCGTCCGCAGTGGGG
CAAAGAGGTGGCGGTGGGTAAAACGCTGGTCTCCTCCGCGATGATTGACCGCGTGGTGAACGATCTGGGCCGCAAGCTGG
TGGAAGTGCCGGTGGGCTTTAAGTGGTTTGTCGACGGCCTGTTCGATGGCAGCTTCGGCTTCGGCGGCGAAGAGAGCGCC
GGGGCCTCCTTCCTGCGCTTCGACGGCACGCCGTGGTCCACCGATAAAGACGGCATCATCATGTGCCTGCTGGCGGCGGA
GATCACCGCGGTGACCGGGAAAAACCCGCAGGAGCATTACAACGAACTGGCGGAACGCTTCGGCGCGCCGAGCTACAACC
GTCTGCAGGCTTCCGCGACCTCCGCGCAGAAAGCGGCGCTGTCCAAGCTCTCTCCGGAAATGGTCAGCGCTGACACCCTG
GCGGGGGATCCGATCACTGCCCGTCTGACCGCGGCGCCGGGCAACGGGGCGGCGATTGGCGGCCTCAAGGTGATGACCGA
CAACGGCTGGTTCGCGGCGCGTCCGTCAGGCACCGAAGACGCCTACAAGATCTACTGCGAAAGCTTCCTCGGCGAAGAGC
ATCGCAAGCTGATTGAAAAAGAAGCGGTAGAGATTGTCAGCGAAGTGCTGAAGAACGCTTAA

Upstream 100 bases:

>100_bases
CCGGCCGTAAATGCAGCATGATTGAGCACATCATGCAGTCGATGCAGTTCCCTGCGGAGCTGATTGAAAAGGTTTGCGGC
ACGATCTAGCTTTTTAACAT

Downstream 100 bases:

>100_bases
CGACGCACTACCATCAGGCCCCTTGCGGGCCTGATTTTTTTCGCAAGGATAGCGATGAAAATACAACGGAAGTCCCTGTT
TTTGTTCTGGGCGTGGATGG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MHQKDQAMAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPHILAIAQAIAEDRA
KNGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDG
GIKYNPPNGGPADTNVTKVVENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGV
DPLGGSGIEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIV
TPAGLMNPNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESA
GASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTL
AGDPITARLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVSEVLKNA

Sequences:

>Translated_553_residues
MHQKDQAMAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPHILAIAQAIAEDRA
KNGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDG
GIKYNPPNGGPADTNVTKVVENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGV
DPLGGSGIEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIV
TPAGLMNPNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESA
GASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTL
AGDPITARLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVSEVLKNA
>Mature_553_residues
MHQKDQAMAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPHILAIAQAIAEDRA
KNGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDG
GIKYNPPNGGPADTNVTKVVENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGV
DPLGGSGIEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIV
TPAGLMNPNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESA
GASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTL
AGDPITARLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVSEVLKNA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=449, Percent_Identity=25.8351893095768, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI133922562, Length=416, Percent_Identity=24.5192307692308, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI21361621, Length=445, Percent_Identity=25.8426966292135, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1786904, Length=546, Percent_Identity=96.1538461538462, Blast_Score=1067, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=537, Percent_Identity=26.0707635009311, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323752, Length=559, Percent_Identity=25.7602862254025, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322722, Length=538, Percent_Identity=27.6951672862454, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17864244, Length=455, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59231; Mature: 59231

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQKDQAMAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAAR
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCCCCHHC
HNFNEPHILAIAQAIAEDRAKNGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQE
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEC
NNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVV
CCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHH
ENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
DPLGGSGIEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLAL
CCCCCCHHHHHHHCCCCEEEEEEEECCCHHHHEEEEEECCCCCEEECCCCHHHHHHHHHH
RDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSA
HHCCCEEECCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
MIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGII
HHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEE
MCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTL
EEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCC
AGDPITARLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEK
CCCCCEEEEEECCCCCCEECCEEEEECCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHHH
EAVEIVSEVLKNA
HHHHHHHHHHHCC
>Mature Secondary Structure
MHQKDQAMAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAAR
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCCCCHHC
HNFNEPHILAIAQAIAEDRAKNGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQE
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEC
NNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVV
CCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHH
ENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
DPLGGSGIEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLAL
CCCCCCHHHHHHHCCCCEEEEEEEECCCHHHHEEEEEECCCCCEEECCCCHHHHHHHHHH
RDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSA
HHCCCEEECCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
MIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGII
HHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEE
MCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTL
EEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCC
AGDPITARLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEK
CCCCCEEEEEECCCCCCEECCEEEEECCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHHH
EAVEIVSEVLKNA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]