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The map label for this gene is ybeM [H]

Identifier: 238893693

GI number: 238893693

Start: 1555214

End: 1556002

Strand: Direct

Name: ybeM [H]

Synonym: KP1_1613

Alternate gene names: 238893693

Gene position: 1555214-1556002 (Clockwise)

Preceding gene: 238893691

Following gene: 238893694

Centisome position: 29.63

GC content: 61.85

Gene sequence:

>789_bases
ATGCGGGTAGCGGCAGGACAATTTGCCGTCACGCCAGTATGGCGGACGAATGCGCAAACCTGTGTGGCGATGATGCAGCA
GGCGGAGCGAGAAGGGGCAGCGCTGCTGGTGCTGCCGGAGGCGTTGCTGGCGCGGGATGACAACGACCCGGATCTGTCAG
TTAAATCGGCCCAGCCGCTGGATGGCGCATTTTTGCAGCCGCTGTTGGCCGAGAGCAGGCGTAACAGCCTGACCACGGTC
CTGACGCTCCATGTGCCGTCAGGGGAGGGGAGAGCGACCAACACCTTGGTGGTATTGCGGGAAGGCGCAGTGATTGCCCA
TTATCATAAACTTCATCTATATGACGCCTTCGCGATGCAGGAGTCCCGGCGGGTGGATCCTGGTCAGCAGATCCCGCCGG
TGATTGAGGTGGCGGGATTACGCGTTGGCCTGATGACCTGCTACGATCTTCGCTTTCCGGAACTGGCGCTTTCGTTGGCC
CTGAATGGGGCACAGCTGCTGGTGCTGCCCGCTGCATGGGTGAAAGGGCCGCAGAAAGAGCATCACTGGGCGACGCTGCT
GGCGGCACGCGCTCTCGATACTACCTGCTATATCGTGGCGGCAGGCGAATGCGGAACGCGCAATATCGGGCTGAGCCGCA
TCGTCGATCCGCTGGGGACCACTCTGGCGGGGGCCGGGAGCGAGCCGCAGCTGATCTTTGCCGATCTCTCTGCGGATGAC
CTTGCGCGCGTTCGCGAGCGTTTACCAGTGCTGCGGAACCGACGATTTGCGCCACCGCAATTATTATGA

Upstream 100 bases:

>100_bases
AGTTGAAACACGGTCGTTTCCTGCTATTTGATGTAAGAGAGTGTCAAGTGTAGCGCGCATCGGGCGCGATTGGCTATCCA
TAACCTGACGGGAGAAGAAC

Downstream 100 bases:

>100_bases
CGTTTTTTTAAACAAGGCTTGATTCACCTTGTTACAGATTGCTATTGTGTCCGCGCGTCAAATACCCGTATTGTTTATCC
CAATAATTCGCTGTGCACGT

Product: putative NAD(P)-binding amidase-type enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MRVAAGQFAVTPVWRTNAQTCVAMMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTV
LTLHVPSGEGRATNTLVVLREGAVIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLA
LNGAQLLVLPAAWVKGPQKEHHWATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADD
LARVRERLPVLRNRRFAPPQLL

Sequences:

>Translated_262_residues
MRVAAGQFAVTPVWRTNAQTCVAMMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTV
LTLHVPSGEGRATNTLVVLREGAVIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLA
LNGAQLLVLPAAWVKGPQKEHHWATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADD
LARVRERLPVLRNRRFAPPQLL
>Mature_262_residues
MRVAAGQFAVTPVWRTNAQTCVAMMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTV
LTLHVPSGEGRATNTLVVLREGAVIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLA
LNGAQLLVLPAAWVKGPQKEHHWATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADD
LARVRERLPVLRNRRFAPPQLL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=273, Percent_Identity=36.2637362637363, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI297632350, Length=273, Percent_Identity=36.2637362637363, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=36.2637362637363, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI9910460, Length=271, Percent_Identity=29.8892988929889, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI297632346, Length=196, Percent_Identity=34.6938775510204, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786412, Length=171, Percent_Identity=29.2397660818713, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=269, Percent_Identity=30.4832713754647, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6322335, Length=298, Percent_Identity=29.5302013422819, Blast_Score=120, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323383, Length=179, Percent_Identity=31.2849162011173, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17933642, Length=265, Percent_Identity=30.188679245283, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355835, Length=270, Percent_Identity=27.037037037037, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28403; Mature: 28403

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAAGQFAVTPVWRTNAQTCVAMMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPL
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEECHHHHHCCCCCCCEEECCCCCC
DGAFLQPLLAESRRNSLTTVLTLHVPSGEGRATNTLVVLREGAVIAHYHKLHLYDAFAMQ
CHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHHH
ESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLALNGAQLLVLPAAWVKGPQKE
HHCCCCCCCCCCCHHHHHCCEEEEHHHCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCH
HHWATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADD
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
LARVRERLPVLRNRRFAPPQLL
HHHHHHHCHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVAAGQFAVTPVWRTNAQTCVAMMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPL
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEECHHHHHCCCCCCCEEECCCCCC
DGAFLQPLLAESRRNSLTTVLTLHVPSGEGRATNTLVVLREGAVIAHYHKLHLYDAFAMQ
CHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHHH
ESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLALNGAQLLVLPAAWVKGPQKE
HHCCCCCCCCCCCHHHHHCCEEEEHHHCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCH
HHWATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADD
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
LARVRERLPVLRNRRFAPPQLL
HHHHHHHCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]