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The map label for this gene is uhpC [H]

Identifier: 238893661

GI number: 238893661

Start: 1521662

End: 1523020

Strand: Reverse

Name: uhpC [H]

Synonym: KP1_1579

Alternate gene names: 238893661

Gene position: 1523020-1521662 (Counterclockwise)

Preceding gene: 238893662

Following gene: 238893660

Centisome position: 29.02

GC content: 61.3

Gene sequence:

>1359_bases
ATGTCTGGAATTATCGCTTTTTTCCGGGCGTCGCCGCCGAAAGCGGGCGCCGCGTTTGATGAACACCGTTTTCGCCGGGT
GCGCTGGCAAACCTTTATCGCCATGACCCTGGCCTACGTCACCTTTTACGTCTGCCGGTTATCCTTCACCGTCGCTAAAA
GCGCGCTGGTGGAGCTGGGGATCACCCCGACGGAGCTCGGCATGATCGGCTCTACCCTGTTCTTCAGCTACGCCATCGGC
AAACTGGTCAATGGTTTTATCGCCGATCACGCCAACGTGGTGCGCTATATGAGCCTCGGTTTATTGCTCAGCGCCGGGAT
GAACCTGATGATGGGGATGACCACCAACGCCCTGCTGCTGGCCATCTTCTGGGGGATCAACGGTTGGGCGCAGTCGATGG
GCGTCGGCCCCTGCGCGGTCTCGCTGGCGCGCTGGTACGGCGTTAAGGAGCGCGGCACCTTCTATGGCATCTGGTCGACG
GCGCATAATATCGGCGAGGCGGTGACCTATATGGTGATCGCCGCGGTGATCGCCGGGTTTGGCTGGCAGATGGGCTACCT
GTCCACCGCCGCGCTCGGCGCCGCCGGCGTGGTGCTGCTGGTGCTGTTCATGCACGATTCGCCGCAGAGCAGCGGCTTCC
CTTCCATCAACGTCATCCGCGATGAACCGCAGGAGGAGGTCGAAGCCCGCGGCTCGGTGTTTAAAAACCAGCTGCTGGCG
CTGCGCAACCCGGCGCTGTGGACCCTCGCCCTCGCCTCCGCCTTTATGTACATCGACCGCTACGCCGTCAACTCCTGGGG
GATCTTCTTTCTCGAGCAGGATAAAGCTTATTCCACCCTGGAGGCGTCCGGGATTATCGGCGTTAACGCTATCGCCGGCA
TCGCCGGGACCATCATCGCCGGCATGCTCTCCGACCGCTTTTTCCCGCGCAACCGCAGCGTGATGGCCGGGTTTATCAGC
CTGCTGAACACCGCCGGCTTCGCCCTGATGCTCTGGTCGCCGCACAATTACTACACTGATATTCTGGCGATGATTATCTT
CGGGGCCACTATTGGCGCTCTGACCTGCTTCCTTGGCGGGCTGATCGCCGTCGATATCTCTTCGCGCAAAGCGGCGGGGG
CCGCGCTCGGCACCATCGGCATCGCCAGCTACGCCGGCGCCGGCCTGGGCGAGTTTCTCACCGGGATCATTATTGATAAA
ACGGCTATCCTTGAGAACGGCAAAACGCTGTATGATTTCAGCACGTTGGCGCTGTTCTGGGTGGGTACCGGTCTGGGTTC
CGCGCTACTCTGTTTTACCACTGCCGCCATCGTCGCCCGGCGCCATGCCGTCGAACGGCAGACCTCGTTCTCCTCATAA

Upstream 100 bases:

>100_bases
TCAGGCTATTTCTGATTATGTACTCTACACAGTAACGATAACTTCATTCACGGACGAACCACATCAATCAGTCAGGCCTC
CGACCTGCGGAGAACCACCT

Downstream 100 bases:

>100_bases
CCGATTAACGAATAAGGAAGAAGATATGATGCCTGCAAGACATCAGGGGCTGTTACGCCTGTTTATCGCCTGCGCGCTGC
CGCTGCTGGCGCTGCAATCT

Product: hypothetical protein

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSGIIAFFRASPPKAGAAFDEHRFRRVRWQTFIAMTLAYVTFYVCRLSFTVAKSALVELGITPTELGMIGSTLFFSYAIG
KLVNGFIADHANVVRYMSLGLLLSAGMNLMMGMTTNALLLAIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIWST
AHNIGEAVTYMVIAAVIAGFGWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINVIRDEPQEEVEARGSVFKNQLLA
LRNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYSTLEASGIIGVNAIAGIAGTIIAGMLSDRFFPRNRSVMAGFIS
LLNTAGFALMLWSPHNYYTDILAMIIFGATIGALTCFLGGLIAVDISSRKAAGAALGTIGIASYAGAGLGEFLTGIIIDK
TAILENGKTLYDFSTLALFWVGTGLGSALLCFTTAAIVARRHAVERQTSFSS

Sequences:

>Translated_452_residues
MSGIIAFFRASPPKAGAAFDEHRFRRVRWQTFIAMTLAYVTFYVCRLSFTVAKSALVELGITPTELGMIGSTLFFSYAIG
KLVNGFIADHANVVRYMSLGLLLSAGMNLMMGMTTNALLLAIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIWST
AHNIGEAVTYMVIAAVIAGFGWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINVIRDEPQEEVEARGSVFKNQLLA
LRNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYSTLEASGIIGVNAIAGIAGTIIAGMLSDRFFPRNRSVMAGFIS
LLNTAGFALMLWSPHNYYTDILAMIIFGATIGALTCFLGGLIAVDISSRKAAGAALGTIGIASYAGAGLGEFLTGIIIDK
TAILENGKTLYDFSTLALFWVGTGLGSALLCFTTAAIVARRHAVERQTSFSS
>Mature_451_residues
SGIIAFFRASPPKAGAAFDEHRFRRVRWQTFIAMTLAYVTFYVCRLSFTVAKSALVELGITPTELGMIGSTLFFSYAIGK
LVNGFIADHANVVRYMSLGLLLSAGMNLMMGMTTNALLLAIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIWSTA
HNIGEAVTYMVIAAVIAGFGWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINVIRDEPQEEVEARGSVFKNQLLAL
RNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYSTLEASGIIGVNAIAGIAGTIIAGMLSDRFFPRNRSVMAGFISL
LNTAGFALMLWSPHNYYTDILAMIIFGATIGALTCFLGGLIAVDISSRKAAGAALGTIGIASYAGAGLGEFLTGIIIDKT
AILENGKTLYDFSTLALFWVGTGLGSALLCFTTAAIVARRHAVERQTSFSS

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219543, Length=276, Percent_Identity=28.6231884057971, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI256219598, Length=276, Percent_Identity=28.6231884057971, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4503847, Length=276, Percent_Identity=28.6231884057971, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI256219483, Length=276, Percent_Identity=28.6231884057971, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI256219564, Length=209, Percent_Identity=27.7511961722488, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI46361976, Length=372, Percent_Identity=23.9247311827957, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI14150047, Length=284, Percent_Identity=24.6478873239437, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788573, Length=399, Percent_Identity=30.3258145363409, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI87082310, Length=414, Percent_Identity=27.7777777777778, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI2367259, Length=417, Percent_Identity=26.6187050359712, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI2367379, Length=418, Percent_Identity=25.8373205741627, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17542316, Length=421, Percent_Identity=23.9904988123515, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133930953, Length=350, Percent_Identity=23.7142857142857, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133901856, Length=393, Percent_Identity=21.3740458015267, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI133901854, Length=393, Percent_Identity=21.3740458015267, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656866, Length=357, Percent_Identity=24.6498599439776, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550478, Length=357, Percent_Identity=24.6498599439776, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24656861, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48443; Mature: 48312

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIIAFFRASPPKAGAAFDEHRFRRVRWQTFIAMTLAYVTFYVCRLSFTVAKSALVELG
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ITPTELGMIGSTLFFSYAIGKLVNGFIADHANVVRYMSLGLLLSAGMNLMMGMTTNALLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
AIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIWSTAHNIGEAVTYMVIAAVIAGF
HHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
GWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINVIRDEPQEEVEARGSVFKNQLLA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
LRNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYSTLEASGIIGVNAIAGIAGTIIA
HCCCHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHH
GMLSDRFFPRNRSVMAGFISLLNTAGFALMLWSPHNYYTDILAMIIFGATIGALTCFLGG
HHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
LIAVDISSRKAAGAALGTIGIASYAGAGLGEFLTGIIIDKTAILENGKTLYDFSTLALFW
CEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHH
VGTGLGSALLCFTTAAIVARRHAVERQTSFSS
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGIIAFFRASPPKAGAAFDEHRFRRVRWQTFIAMTLAYVTFYVCRLSFTVAKSALVELG
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ITPTELGMIGSTLFFSYAIGKLVNGFIADHANVVRYMSLGLLLSAGMNLMMGMTTNALLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
AIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIWSTAHNIGEAVTYMVIAAVIAGF
HHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
GWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINVIRDEPQEEVEARGSVFKNQLLA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
LRNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYSTLEASGIIGVNAIAGIAGTIIA
HCCCHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHH
GMLSDRFFPRNRSVMAGFISLLNTAGFALMLWSPHNYYTDILAMIIFGATIGALTCFLGG
HHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
LIAVDISSRKAAGAALGTIGIASYAGAGLGEFLTGIIIDKTAILENGKTLYDFSTLALFW
CEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHH
VGTGLGSALLCFTTAAIVARRHAVERQTSFSS
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]