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The map label for this gene is mtnA [H]

Identifier: 238893659

GI number: 238893659

Start: 1519279

End: 1520307

Strand: Direct

Name: mtnA [H]

Synonym: KP1_1577

Alternate gene names: 238893659

Gene position: 1519279-1520307 (Clockwise)

Preceding gene: 238893657

Following gene: 238893667

Centisome position: 28.95

GC content: 65.89

Gene sequence:

>1029_bases
ATGCAGACATTACAGACCACCAGCCTGCGGGTGAGTGAAAATCAGCTTTTTATTCTCGACCAGCAGGCCTTGCCGCAGGA
ACAACGCTGGCTGGCGGCGGATAACGTTGCGCTGCTGGTGGACCATATTCATACCCTGCGGGTGCGCGGCGCGCCGCTGA
TTGGCCTGTCCGCCAGCCTGCTGCTGGCCCTGCTGGCCCAGCGCGGCCTGAACCGGGATGCACTCCAGCAGGCGCTGGAG
ACGCTGCGCGCGGCGCGGCCGACGGCGGTCAACCTGATGAATAATCTGGATCGCATGAAGCAGGCGCTGGCCCGGGAGGA
TTACCCGCAGGCGCTGGAAGCGGAAGCCTTGCGTCTGGTCGAAGAAGATAAACAGCTGTGCGACCGCATCGCTGAGGCGG
GCAGTGCGCTGGTGAAGCCCGGCAGTCGACTGCTGACCCACTGCAACACCGGTGGCCTGGCGACCGCCGGGGTAGGGACC
GCCCTGGGCGTTATCGCGCTGGCGCACCGGCAGGGAAAGGTGACCAACGTATGGGTTGATGAAACCCGGCCGCTGCTGCA
GGGCGGTCGTTTAACCGCCTGGGAGCTGGGCGAGCTGGGCGTGCCCTATCAGCTGATCGCCGATTCAATGGCCGCCAGCC
TGATGGCGCAGGGGCAGGTGGATGCGGTGTGGGTCGGCGCCGACCGTATCGCCGCCAACGGCGACGTGGCGAATAAAATC
GGCACCTATTCTCTGGCGGTTTTGGCCCATTATCACCAGATCCCGTTTTACGTCGCTGCCCCGCAGACCACCCTCGATCG
CTATTGCCCGAACGGGGCGGCCATTCCCATTGAGCAGCGCGCCGCGGCCGAAGTGACCGGAGTGGCGGGCAGCTTTGGCG
CGGTACAGTGGGCGCCGACGGGGGCTGCCGTTTACAATCCGGCGTTCGACGTCACGCCTGCTGGGCTGATAAGCGGCTGG
GTGCTGGACAGCGGGGTGGTCACCCCGGCGCAGGTCGCCGCCGGGGCGTTTGCGCCGGACAATGGATAA

Upstream 100 bases:

>100_bases
GCCTCGATCCTCGAATTCTGATTAAGCCGTTCAGACGTCTATACTTCTGGATTCCATCCTGACACAATGTGATACAACAA
CGCAACAGGGATTTAACGAC

Downstream 100 bases:

>100_bases
CGGACGTCGTGCCGGGCCTGGAAAAAAAGGTTTTCCCGGGCCCGGACAAACACCGCGCCGCTACGGCAGGACCATGGCTA
CCGCCGGGGCGGATGATCGG

Product: S-methyl-5-thioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQTLQTTSLRVSENQLFILDQQALPQEQRWLAADNVALLVDHIHTLRVRGAPLIGLSASLLLALLAQRGLNRDALQQALE
TLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCDRIAEAGSALVKPGSRLLTHCNTGGLATAGVGT
ALGVIALAHRQGKVTNVWVDETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLISGW
VLDSGVVTPAQVAAGAFAPDNG

Sequences:

>Translated_342_residues
MQTLQTTSLRVSENQLFILDQQALPQEQRWLAADNVALLVDHIHTLRVRGAPLIGLSASLLLALLAQRGLNRDALQQALE
TLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCDRIAEAGSALVKPGSRLLTHCNTGGLATAGVGT
ALGVIALAHRQGKVTNVWVDETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLISGW
VLDSGVVTPAQVAAGAFAPDNG
>Mature_342_residues
MQTLQTTSLRVSENQLFILDQQALPQEQRWLAADNVALLVDHIHTLRVRGAPLIGLSASLLLALLAQRGLNRDALQQALE
TLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCDRIAEAGSALVKPGSRLLTHCNTGGLATAGVGT
ALGVIALAHRQGKVTNVWVDETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLISGW
VLDSGVVTPAQVAAGAFAPDNG

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=362, Percent_Identity=41.1602209944751, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI23943880, Length=341, Percent_Identity=38.7096774193548, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI4503503, Length=207, Percent_Identity=30.4347826086957, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17557462, Length=331, Percent_Identity=42.5981873111783, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17557123, Length=285, Percent_Identity=27.3684210526316, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325375, Length=391, Percent_Identity=33.5038363171356, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6322878, Length=273, Percent_Identity=27.1062271062271, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357667, Length=355, Percent_Identity=41.1267605633803, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24651647, Length=355, Percent_Identity=41.1267605633803, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 36158; Mature: 36158

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLQTTSLRVSENQLFILDQQALPQEQRWLAADNVALLVDHIHTLRVRGAPLIGLSASL
CCCCCCCEEEECCCEEEEEEHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCEECHHHHH
LLALLAQRGLNRDALQQALETLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLV
HHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EEDKQLCDRIAEAGSALVKPGSRLLTHCNTGGLATAGVGTALGVIALAHRQGKVTNVWVD
HHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
ETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
CCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHH
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPT
HHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCC
GAAVYNPAFDVTPAGLISGWVLDSGVVTPAQVAAGAFAPDNG
CCEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MQTLQTTSLRVSENQLFILDQQALPQEQRWLAADNVALLVDHIHTLRVRGAPLIGLSASL
CCCCCCCEEEECCCEEEEEEHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCEECHHHHH
LLALLAQRGLNRDALQQALETLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLV
HHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EEDKQLCDRIAEAGSALVKPGSRLLTHCNTGGLATAGVGTALGVIALAHRQGKVTNVWVD
HHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
ETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
CCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHH
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPT
HHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCC
GAAVYNPAFDVTPAGLISGWVLDSGVVTPAQVAAGAFAPDNG
CCEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA