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The map label for this gene is fepD [H]

Identifier: 238893639

GI number: 238893639

Start: 1498680

End: 1499687

Strand: Reverse

Name: fepD [H]

Synonym: KP1_1553

Alternate gene names: 238893639

Gene position: 1499687-1498680 (Counterclockwise)

Preceding gene: 238893640

Following gene: 238893638

Centisome position: 28.57

GC content: 68.55

Gene sequence:

>1008_bases
ATGTCGTTTTCTACGACCGCGGTACGCTCTGTCGCCGTGCCCGGATTGTTGCTATTACTCGCCTTAGCCGCCGCGCTTAG
CCTGACCATCGGCGCCAAATCGTTGCCGATCGGCACGGTATTCACCGCCTTCAGCGGAACCTGTCAAAGCGCTGATTGCA
CTATCGTGCTGGACGCGCGCCTGCCGCGCACTCTGGCCGGTCTGCTGGCCGGCGTCGCCCTCGGCCTCGCCGGCGCGCTG
ATGCAGACGCTCACCCGCAACCCGCTGGCCGACCCCGGCCTGCTGGGGGTCAACTCCGGCGCCAGCTTCGCCATCGTCCT
CGGCGCGGCGCTGTTTGGGATCACTTCCCCGCAGGAGCAGCTGCTGCTGGCATTCTGCGGCGCGCTCTGCGCCTCGCTGC
TGGTAGCCTTTACCGGCAGCCAGGGCGGCGGTCAGCTGAGCCCGGTGCGCCTCACTCTCGCCGGGGTCGCCCTTGCGGCG
GTACTCGAGGGGCTGTCCAACGGCATCGCCCTGCTCAACCCGGACGTCTACGATCAGCTACGCTTCTGGCAGGCCGGTTC
GCTGGATATCCGCACCCTGCAAACGCTGAAAATTGTCCTGCTGCCGGTAGTGGTGGCGGGGATCGCCGCTCTGCTGCTGA
GCCGGGCGCTGAACAGCCTGAGCCTGGGCAACGATACCGCCACCGCCCTCGGCAGCCGCGTCGCCCGTACCCAGCTGATC
GGCCTGATCGTCATCACCGTCCTGTGCGGCAGCGCCACCGCCGTCGTCGGCCCCATCGCCTTTATCGGCCTGATGATGCC
GCATATGGCGCGCTGGCTGGTGGGGGCCGATCATCGCTGGTCGCTGCCGGTCACCCTGCTCGCCACCCCGGCCCTGCTGC
TGTTTGCCGACGTGATTGGCCGCCTGCTGGTGCCCGGCGAACTGCGGGTATCGGTGGTGAGCGCCTTTCTCGGCGCGCCG
GTGCTGATCTGGCTGGTGCGCCGCCAGCCGCGGGGAGGTGGCCTGTGA

Upstream 100 bases:

>100_bases
TCGTTATTTTTAATACCCTTTTTACTGTGGGTCATGCTACCATAGCTGAATAAAATCGATAACGATAATTACTATCATTA
TCATATCAGGGATGTCAGTT

Downstream 100 bases:

>100_bases
TTGCCCCGTCCCGCCGCCTGATAGCCAGCTGTCTGCTGCTAATGGCCGCCAGCCTGCTGATTTCCCTGCTCGGGCTGGCG
CAAGGCCCGGTGCCCCTGAC

Product: iron-enterobactin transporter membrane protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSFSTTAVRSVAVPGLLLLLALAAALSLTIGAKSLPIGTVFTAFSGTCQSADCTIVLDARLPRTLAGLLAGVALGLAGAL
MQTLTRNPLADPGLLGVNSGASFAIVLGAALFGITSPQEQLLLAFCGALCASLLVAFTGSQGGGQLSPVRLTLAGVALAA
VLEGLSNGIALLNPDVYDQLRFWQAGSLDIRTLQTLKIVLLPVVVAGIAALLLSRALNSLSLGNDTATALGSRVARTQLI
GLIVITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADVIGRLLVPGELRVSVVSAFLGAP
VLIWLVRRQPRGGGL

Sequences:

>Translated_335_residues
MSFSTTAVRSVAVPGLLLLLALAAALSLTIGAKSLPIGTVFTAFSGTCQSADCTIVLDARLPRTLAGLLAGVALGLAGAL
MQTLTRNPLADPGLLGVNSGASFAIVLGAALFGITSPQEQLLLAFCGALCASLLVAFTGSQGGGQLSPVRLTLAGVALAA
VLEGLSNGIALLNPDVYDQLRFWQAGSLDIRTLQTLKIVLLPVVVAGIAALLLSRALNSLSLGNDTATALGSRVARTQLI
GLIVITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADVIGRLLVPGELRVSVVSAFLGAP
VLIWLVRRQPRGGGL
>Mature_334_residues
SFSTTAVRSVAVPGLLLLLALAAALSLTIGAKSLPIGTVFTAFSGTCQSADCTIVLDARLPRTLAGLLAGVALGLAGALM
QTLTRNPLADPGLLGVNSGASFAIVLGAALFGITSPQEQLLLAFCGALCASLLVAFTGSQGGGQLSPVRLTLAGVALAAV
LEGLSNGIALLNPDVYDQLRFWQAGSLDIRTLQTLKIVLLPVVVAGIAALLLSRALNSLSLGNDTATALGSRVARTQLIG
LIVITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADVIGRLLVPGELRVSVVSAFLGAPV
LIWLVRRQPRGGGL

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=333, Percent_Identity=85.8858858858859, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=40.8602150537634, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790740, Length=314, Percent_Identity=36.624203821656, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786804, Length=308, Percent_Identity=36.3636363636364, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786347, Length=327, Percent_Identity=34.8623853211009, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=38.0281690140845, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34174; Mature: 34043

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSTTAVRSVAVPGLLLLLALAAALSLTIGAKSLPIGTVFTAFSGTCQSADCTIVLDAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEECCC
LPRTLAGLLAGVALGLAGALMQTLTRNPLADPGLLGVNSGASFAIVLGAALFGITSPQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCHHHH
LLLAFCGALCASLLVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLSNGIALLNPDVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHH
RFWQAGSLDIRTLQTLKIVLLPVVVAGIAALLLSRALNSLSLGNDTATALGSRVARTQLI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLIVITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADVIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RLLVPGELRVSVVSAFLGAPVLIWLVRRQPRGGGL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SFSTTAVRSVAVPGLLLLLALAAALSLTIGAKSLPIGTVFTAFSGTCQSADCTIVLDAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEECCC
LPRTLAGLLAGVALGLAGALMQTLTRNPLADPGLLGVNSGASFAIVLGAALFGITSPQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCHHHH
LLLAFCGALCASLLVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLSNGIALLNPDVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHH
RFWQAGSLDIRTLQTLKIVLLPVVVAGIAALLLSRALNSLSLGNDTATALGSRVARTQLI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLIVITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADVIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RLLVPGELRVSVVSAFLGAPVLIWLVRRQPRGGGL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]