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The map label for this gene is glmS [H]

Identifier: 238893573

GI number: 238893573

Start: 1425279

End: 1426322

Strand: Reverse

Name: glmS [H]

Synonym: KP1_1481

Alternate gene names: 238893573

Gene position: 1426322-1425279 (Counterclockwise)

Preceding gene: 238893574

Following gene: 238893572

Centisome position: 27.18

GC content: 56.03

Gene sequence:

>1044_bases
ATGAATGAAACACCCGCCTGTCTGCTCGCTATGCTGACGCAGACGCGGGAAGATCTCTGGCAGGCGGCAAAAGCGCTAAC
GGAGCGCGGCGTCACGCGTATTATCCTGACCGGCTCCGGTACCTCTTATCACGGCGCGCTGACCGCCCGCTCGTTTATGC
AGCAGTGGTGCGGGCTACCCGTTGATGTCTACTGGCCTTTTCTGCTGGATGATTCGGCGCTGACCCTCAGCGACAAAGCG
CTGGTCATCGGTATTTCTCAGGGAGGCGGCAGCCTCTCTACCCTCGCCGCAATGGAACGCGCCCGGGCAGCCGGGCATCT
TACCGCTTCCATGGCCGGGGAAGCGCCAGCCGTTATCGACCGGGCGGCAGATTTGGTCTTAACAGTACCCTGTGGAGAAG
AGCGGGCTGGCGCCAAAACCAAAGGGTATCACTGCACCATACTTAATCTGATGCTGCTAACGCTTGCTGTCGCCAGTCGC
CAGCGGCGCCTGAGCGATGAGGAGCGCAAGGCGCTACTCGTCCGCATGGATACCACGTTTAATCATTTGCCGACGCTCAT
TGAGGCCTCGCAGGCGTGGGTTCTCAATCATGCCCGACCGCTTATCGACAGCGCGGACATTCGCCTGACCGGTCCGGCAA
GGCTGTTTGGCACCGTTCAGGAAGGTGCGCTAAAGATGCTTGAAACGCTACGCTGTCCGGTTGCCGGTTACGAATTTGAG
GAGTTCATCCACGGGATCTATAACGCCTTCGACGAGCGCTCTACCCTGATCATGCTCGATCCGTTTCCCGATGAGCGTCA
GGATCGCCTGGCGGAAATACTTGGCGGCTGGACTCAGCATATTTATCGCATTGGTCCACAAGTCGAAAATAACGGCAAAA
ATATGCCCTTCGCATTTATTAACGATCCCGACTTTGCGGTCTTTGAATATATTATTCCGTTACAAATGGTTTGTGCCCGA
CTGCCGCCAGTGAAGGGCATCGATCCCGCAATACCGAAGGATCCGCATTTCCACCAGAAAATGAAAAGTAAACAACTCAA
TTAA

Upstream 100 bases:

>100_bases
TTAACTGGATCCTGCTAGGAACCGTCGCGTTTGGCATGGCGGCCAGCGCGCTAGGCCTGCTTTAAGAAGAGGAATATCAC
CTATGCACGTAGAAGACTAT

Downstream 100 bases:

>100_bases
TTGACGCATAGTAAAAGTTATCCGCGTTTCAGCGGAGGACCCGTTACATCCCAAGGAGACCAATATGTCTATAGCTCATC
AAAACGCACATACTATTATT

Product: putative inner membrane protein

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNETPACLLAMLTQTREDLWQAAKALTERGVTRIILTGSGTSYHGALTARSFMQQWCGLPVDVYWPFLLDDSALTLSDKA
LVIGISQGGGSLSTLAAMERARAAGHLTASMAGEAPAVIDRAADLVLTVPCGEERAGAKTKGYHCTILNLMLLTLAVASR
QRRLSDEERKALLVRMDTTFNHLPTLIEASQAWVLNHARPLIDSADIRLTGPARLFGTVQEGALKMLETLRCPVAGYEFE
EFIHGIYNAFDERSTLIMLDPFPDERQDRLAEILGGWTQHIYRIGPQVENNGKNMPFAFINDPDFAVFEYIIPLQMVCAR
LPPVKGIDPAIPKDPHFHQKMKSKQLN

Sequences:

>Translated_347_residues
MNETPACLLAMLTQTREDLWQAAKALTERGVTRIILTGSGTSYHGALTARSFMQQWCGLPVDVYWPFLLDDSALTLSDKA
LVIGISQGGGSLSTLAAMERARAAGHLTASMAGEAPAVIDRAADLVLTVPCGEERAGAKTKGYHCTILNLMLLTLAVASR
QRRLSDEERKALLVRMDTTFNHLPTLIEASQAWVLNHARPLIDSADIRLTGPARLFGTVQEGALKMLETLRCPVAGYEFE
EFIHGIYNAFDERSTLIMLDPFPDERQDRLAEILGGWTQHIYRIGPQVENNGKNMPFAFINDPDFAVFEYIIPLQMVCAR
LPPVKGIDPAIPKDPHFHQKMKSKQLN
>Mature_347_residues
MNETPACLLAMLTQTREDLWQAAKALTERGVTRIILTGSGTSYHGALTARSFMQQWCGLPVDVYWPFLLDDSALTLSDKA
LVIGISQGGGSLSTLAAMERARAAGHLTASMAGEAPAVIDRAADLVLTVPCGEERAGAKTKGYHCTILNLMLLTLAVASR
QRRLSDEERKALLVRMDTTFNHLPTLIEASQAWVLNHARPLIDSADIRLTGPARLFGTVQEGALKMLETLRCPVAGYEFE
EFIHGIYNAFDERSTLIMLDPFPDERQDRLAEILGGWTQHIYRIGPQVENNGKNMPFAFINDPDFAVFEYIIPLQMVCAR
LPPVKGIDPAIPKDPHFHQKMKSKQLN

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=317, Percent_Identity=24.9211356466877, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI205277386, Length=313, Percent_Identity=23.3226837060703, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1790167, Length=320, Percent_Identity=22.8125, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17539970, Length=230, Percent_Identity=27.8260869565217, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17532899, Length=230, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17532897, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322745, Length=322, Percent_Identity=23.9130434782609, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357745, Length=310, Percent_Identity=22.9032258064516, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 38357; Mature: 38357

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETPACLLAMLTQTREDLWQAAKALTERGVTRIILTGSGTSYHGALTARSFMQQWCGLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
VDVYWPFLLDDSALTLSDKALVIGISQGGGSLSTLAAMERARAAGHLTASMAGEAPAVID
CEEEEHEEECCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RAADLVLTVPCGEERAGAKTKGYHCTILNLMLLTLAVASRQRRLSDEERKALLVRMDTTF
CCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCH
NHLPTLIEASQAWVLNHARPLIDSADIRLTGPARLFGTVQEGALKMLETLRCPVAGYEFE
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
EFIHGIYNAFDERSTLIMLDPFPDERQDRLAEILGGWTQHIYRIGPQVENNGKNMPFAFI
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
NDPDFAVFEYIIPLQMVCARLPPVKGIDPAIPKDPHFHQKMKSKQLN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MNETPACLLAMLTQTREDLWQAAKALTERGVTRIILTGSGTSYHGALTARSFMQQWCGLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
VDVYWPFLLDDSALTLSDKALVIGISQGGGSLSTLAAMERARAAGHLTASMAGEAPAVID
CEEEEHEEECCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RAADLVLTVPCGEERAGAKTKGYHCTILNLMLLTLAVASRQRRLSDEERKALLVRMDTTF
CCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCH
NHLPTLIEASQAWVLNHARPLIDSADIRLTGPARLFGTVQEGALKMLETLRCPVAGYEFE
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
EFIHGIYNAFDERSTLIMLDPFPDERQDRLAEILGGWTQHIYRIGPQVENNGKNMPFAFI
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
NDPDFAVFEYIIPLQMVCARLPPVKGIDPAIPKDPHFHQKMKSKQLN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA