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The map label for this gene is ybbK [H]

Identifier: 238893455

GI number: 238893455

Start: 1299528

End: 1300445

Strand: Reverse

Name: ybbK [H]

Synonym: KP1_1346

Alternate gene names: 238893455

Gene position: 1300445-1299528 (Counterclockwise)

Preceding gene: 238893458

Following gene: 238893454

Centisome position: 24.78

GC content: 58.39

Gene sequence:

>918_bases
ATGCTGATTTTTATTCCTATCCTTATTTTCGTCGCGCTGGTTATTGTGGCCGCGGCGGTGAAAATTGTCCCGCAGGGCTA
CCAGTGGACGGTGGAGCGCTTCGGGCGTTTTACCCAGACGCTGCAGCCGGGATTAAGCTTAGTCGTGCCGTTTATGGACC
GTATCGGCCGCAAAGTGAACATGATGGAGCAGGTGCTCGATATCCCCTCGCAGGAGGTTATCTCCCGGGATAACGCCAAC
GTCACCATCGACGCGGTCTGTTTTATTCAGGTGATCGACGCGCCAAAGGCCGCCTACGAGGTCAGCAATCTTGAGCAGGC
GATCGTCAACCTGACGATGACCAACATCCGTACCGTGCTCGGCTCAATGGAGCTGGACGAAATGCTCTCCCAGCGCGACA
GCATTAACACCCGCCTGCTGCATATCGTTGACGACGCCACCAACCCGTGGGGGGTGAAAATCACCCGCGTCGAAATTCGC
GACGTTCGCCCGCCGGCGGAGCTTATCGCCTCGATGAACGCCCAGATGAAAGCCGAACGTACCAAACGCGCGTACATCCT
TGAGGCCGAAGGGGTGCGACAGGCGGAAATTCTGAAAGCGGAAGGGGAAAAGCAGTCGCAGATCCTCAAGGCCGAGGGCG
AACGGCAGTCCGCGTTCCTGCAGGCGGAGGCTCGCGAACGGTCCGCCGAAGCGGAAGCCCGCGCCACCCAAATGGTCTCC
TCGGCGATCGCCTCGGGCGATATTCAGGCGATCAACTACTTCGTGGCGCAGAAATACACCGATGCGCTGCAGCAGATTGG
CGCCGCTAACAACAGCAAAGTGGTATTGATGCCGCTGGATGCCAGCAGCCTGATGGGATCGATCGCCGGGATCAGCGAGC
TGATCAAAGAAGGCGCTGGCGATCGGAAAAAATCATGA

Upstream 100 bases:

>100_bases
GCACTTTCCTTTCTCCAGGATGAGGAGAAAGATATACTCAGTTTAAACATGCGCTATTTCCTTGTAGCGCCCCGCCAGGC
AACAAGACAGGAGGTTTTTG

Downstream 100 bases:

>100_bases
TCGGCATGATCCTCGCACACCCCCATCTGTTCTGGCTAAGCCTCGGCGGGCTGCTGCTGGCGGCCGAGATGCTGGGCGGC
AGCGGATACCTGCTGTGGAG

Product: putative protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLIFIPILIFVALVIVAAAVKIVPQGYQWTVERFGRFTQTLQPGLSLVVPFMDRIGRKVNMMEQVLDIPSQEVISRDNAN
VTIDAVCFIQVIDAPKAAYEVSNLEQAIVNLTMTNIRTVLGSMELDEMLSQRDSINTRLLHIVDDATNPWGVKITRVEIR
DVRPPAELIASMNAQMKAERTKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
SAIASGDIQAINYFVAQKYTDALQQIGAANNSKVVLMPLDASSLMGSIAGISELIKEGAGDRKKS

Sequences:

>Translated_305_residues
MLIFIPILIFVALVIVAAAVKIVPQGYQWTVERFGRFTQTLQPGLSLVVPFMDRIGRKVNMMEQVLDIPSQEVISRDNAN
VTIDAVCFIQVIDAPKAAYEVSNLEQAIVNLTMTNIRTVLGSMELDEMLSQRDSINTRLLHIVDDATNPWGVKITRVEIR
DVRPPAELIASMNAQMKAERTKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
SAIASGDIQAINYFVAQKYTDALQQIGAANNSKVVLMPLDASSLMGSIAGISELIKEGAGDRKKS
>Mature_305_residues
MLIFIPILIFVALVIVAAAVKIVPQGYQWTVERFGRFTQTLQPGLSLVVPFMDRIGRKVNMMEQVLDIPSQEVISRDNAN
VTIDAVCFIQVIDAPKAAYEVSNLEQAIVNLTMTNIRTVLGSMELDEMLSQRDSINTRLLHIVDDATNPWGVKITRVEIR
DVRPPAELIASMNAQMKAERTKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
SAIASGDIQAINYFVAQKYTDALQQIGAANNSKVVLMPLDASSLMGSIAGISELIKEGAGDRKKS

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=281, Percent_Identity=34.8754448398576, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI21686995, Length=193, Percent_Identity=35.7512953367876, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI221316744, Length=193, Percent_Identity=35.7512953367876, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI38016911, Length=205, Percent_Identity=33.6585365853659, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI7657615, Length=178, Percent_Identity=29.2134831460674, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786697, Length=304, Percent_Identity=88.8157894736842, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1790616, Length=198, Percent_Identity=24.7474747474747, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32564147, Length=299, Percent_Identity=33.7792642140468, Blast_Score=171, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17569493, Length=217, Percent_Identity=34.5622119815668, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI193209764, Length=217, Percent_Identity=34.5622119815668, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71987612, Length=198, Percent_Identity=34.8484848484849, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25153583, Length=192, Percent_Identity=35.4166666666667, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17569497, Length=193, Percent_Identity=31.0880829015544, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71987621, Length=218, Percent_Identity=33.9449541284404, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71989948, Length=156, Percent_Identity=36.5384615384615, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71989955, Length=156, Percent_Identity=36.5384615384615, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17569499, Length=193, Percent_Identity=33.160621761658, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17570459, Length=205, Percent_Identity=34.6341463414634, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193210507, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17570161, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32566490, Length=219, Percent_Identity=30.5936073059361, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71989963, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45550506, Length=276, Percent_Identity=36.9565217391304, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI45556022, Length=193, Percent_Identity=35.2331606217617, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI62484448, Length=199, Percent_Identity=34.6733668341709, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281365664, Length=199, Percent_Identity=34.6733668341709, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI62484274, Length=199, Percent_Identity=34.6733668341709, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24657857, Length=199, Percent_Identity=34.6733668341709, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI18860517, Length=199, Percent_Identity=31.6582914572864, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356845, Length=191, Percent_Identity=27.2251308900524, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281361631, Length=189, Percent_Identity=28.042328042328, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281361633, Length=189, Percent_Identity=28.042328042328, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28573263, Length=198, Percent_Identity=25.7575757575758, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281361635, Length=131, Percent_Identity=27.4809160305344, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33561; Mature: 33561

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS01270 BAND_7

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFIPILIFVALVIVAAAVKIVPQGYQWTVERFGRFTQTLQPGLSLVVPFMDRIGRKVN
CEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISRDNANVTIDAVCFIQVIDAPKAAYEVSNLEQAIVNLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GSMELDEMLSQRDSINTRLLHIVDDATNPWGVKITRVEIRDVRPPAELIASMNAQMKAER
CCCCHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHHHH
TKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
HHHEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIASGDIQAINYFVAQKYTDALQQIGAANNSKVVLMPLDASSLMGSIAGISELIKEGAG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
DRKKS
CCCCC
>Mature Secondary Structure
MLIFIPILIFVALVIVAAAVKIVPQGYQWTVERFGRFTQTLQPGLSLVVPFMDRIGRKVN
CEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISRDNANVTIDAVCFIQVIDAPKAAYEVSNLEQAIVNLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GSMELDEMLSQRDSINTRLLHIVDDATNPWGVKITRVEIRDVRPPAELIASMNAQMKAER
CCCCHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHHHH
TKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
HHHEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIASGDIQAINYFVAQKYTDALQQIGAANNSKVVLMPLDASSLMGSIAGISELIKEGAG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
DRKKS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]