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The map label for this gene is aroE [H]

Identifier: 238893372

GI number: 238893372

Start: 1212685

End: 1213506

Strand: Reverse

Name: aroE [H]

Synonym: KP1_1255

Alternate gene names: 238893372

Gene position: 1213506-1212685 (Counterclockwise)

Preceding gene: 238893374

Following gene: 238893371

Centisome position: 23.12

GC content: 65.45

Gene sequence:

>822_bases
ATGGTCAGTGGAACTACCCAGGTTGTCGCCGTGATTGGTCATCCGATCGCCCAGGTGAAATCACCGGATAACTTCAACCG
CTACTTTGCCGAACAGCACATGGACAGCGTCATGATCCCGGTGGATATCGTCCCGGACGCGGTGGCCGCCTACCTCAACG
CCCTGCGCGGCTGGCAGAACATGACCGGAGTGCTGGTGACGGTGCCGCATAAACAACGCGCCGCCGCGCTGGTCGACGAC
CTCACGCCGCGCGCCCGCCGACTCAACGCCGTCAATGTGATCCGCAAGCTGGCGGATGGCCGCCTGCAGGGCGATATGCT
GGACGGCGTCGGCTTTCAGCTCGCCGCCGAGGCGCAGGGTTTTCAGCCGGCAGGTAAGCAGGCGCTGCTCTCCGGTTGCG
GCGGCGTCGGCAGCGCCATCGCCTGGGGACTGTGCGAGGCGGGGATCCGTCGGCTGGCCCTACACGATCAAACCCCGGCC
ACCCGGCAGCGCCTGCATGACCTTCTGGCTGAGGCCTTTCCGGCGGTGCAACTGAGCGCGCTGCCAGACACCCTTTACGG
CCTCGATCTACTGGTTAATGGCTCACCGGCCGGCATGGCCGGATTTGATGAGCTGCCTCTACCGCAGGCGCTGCTGGATA
CGCTCGACAGCACCACTCATGTGGCCGACGTTGTCACCGCCCCGGTAATGACGCCGTTGCTCACTTTCGCCGCCGCCCGT
GGTTGCAAAGTACAGACCGGGCCGGAAATGGCGCTGGCGCAGATGAGGCTGATGGGCCAGTTTATCGGCGCCATCCCGCA
GGCGCAGGGAGCGGCGGCATGA

Upstream 100 bases:

>100_bases
GTTCGTGCGATTAACAACCGACATGTCCGAATTCTGCGTTGTCGCTCCCAGCTTCCACTGAAATACTTTCACAACATTCA
TTTAACAAATGAGGTTTGAA

Downstream 100 bases:

>100_bases
AGAGCTGGGATGTGATCGTCATCGGCAGCGGCGCGGCCGGTTTTGCCGCCGCGGTCACCGCCTGCTGTAAAGGGCTGTCG
GTGCTGATGCTGGAGAAAGC

Product: shikimate/quinate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MVSGTTQVVAVIGHPIAQVKSPDNFNRYFAEQHMDSVMIPVDIVPDAVAAYLNALRGWQNMTGVLVTVPHKQRAAALVDD
LTPRARRLNAVNVIRKLADGRLQGDMLDGVGFQLAAEAQGFQPAGKQALLSGCGGVGSAIAWGLCEAGIRRLALHDQTPA
TRQRLHDLLAEAFPAVQLSALPDTLYGLDLLVNGSPAGMAGFDELPLPQALLDTLDSTTHVADVVTAPVMTPLLTFAAAR
GCKVQTGPEMALAQMRLMGQFIGAIPQAQGAAA

Sequences:

>Translated_273_residues
MVSGTTQVVAVIGHPIAQVKSPDNFNRYFAEQHMDSVMIPVDIVPDAVAAYLNALRGWQNMTGVLVTVPHKQRAAALVDD
LTPRARRLNAVNVIRKLADGRLQGDMLDGVGFQLAAEAQGFQPAGKQALLSGCGGVGSAIAWGLCEAGIRRLALHDQTPA
TRQRLHDLLAEAFPAVQLSALPDTLYGLDLLVNGSPAGMAGFDELPLPQALLDTLDSTTHVADVVTAPVMTPLLTFAAAR
GCKVQTGPEMALAQMRLMGQFIGAIPQAQGAAA
>Mature_273_residues
MVSGTTQVVAVIGHPIAQVKSPDNFNRYFAEQHMDSVMIPVDIVPDAVAAYLNALRGWQNMTGVLVTVPHKQRAAALVDD
LTPRARRLNAVNVIRKLADGRLQGDMLDGVGFQLAAEAQGFQPAGKQALLSGCGGVGSAIAWGLCEAGIRRLALHDQTPA
TRQRLHDLLAEAFPAVQLSALPDTLYGLDLLVNGSPAGMAGFDELPLPQALLDTLDSTTHVADVVTAPVMTPLLTFAAAR
GCKVQTGPEMALAQMRLMGQFIGAIPQAQGAAA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=267, Percent_Identity=29.9625468164794, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789675, Length=244, Percent_Identity=31.5573770491803, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28702; Mature: 28702

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSGTTQVVAVIGHPIAQVKSPDNFNRYFAEQHMDSVMIPVDIVPDAVAAYLNALRGWQN
CCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCEEECHHHCHHHHHHHHHHHHHHHC
MTGVLVTVPHKQRAAALVDDLTPRARRLNAVNVIRKLADGRLQGDMLDGVGFQLAAEAQG
CCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEECCCCC
FQPAGKQALLSGCGGVGSAIAWGLCEAGIRRLALHDQTPATRQRLHDLLAEAFPAVQLSA
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
LPDTLYGLDLLVNGSPAGMAGFDELPLPQALLDTLDSTTHVADVVTAPVMTPLLTFAAAR
CCHHHHCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GCKVQTGPEMALAQMRLMGQFIGAIPQAQGAAA
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVSGTTQVVAVIGHPIAQVKSPDNFNRYFAEQHMDSVMIPVDIVPDAVAAYLNALRGWQN
CCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCEEECHHHCHHHHHHHHHHHHHHHC
MTGVLVTVPHKQRAAALVDDLTPRARRLNAVNVIRKLADGRLQGDMLDGVGFQLAAEAQG
CCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEECCCCC
FQPAGKQALLSGCGGVGSAIAWGLCEAGIRRLALHDQTPATRQRLHDLLAEAFPAVQLSA
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
LPDTLYGLDLLVNGSPAGMAGFDELPLPQALLDTLDSTTHVADVVTAPVMTPLLTFAAAR
CCHHHHCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GCKVQTGPEMALAQMRLMGQFIGAIPQAQGAAA
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA