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The map label for this gene is ksdD [H]

Identifier: 238893369

GI number: 238893369

Start: 1208970

End: 1210667

Strand: Reverse

Name: ksdD [H]

Synonym: KP1_1252

Alternate gene names: 238893369

Gene position: 1210667-1208970 (Counterclockwise)

Preceding gene: 238893370

Following gene: 238893368

Centisome position: 23.07

GC content: 66.73

Gene sequence:

>1698_bases
ATGAGCGGGCCTGTGAAGGTGGATGTGCTGGTGGTCGGCTCCGGCGCCGCGGGGCTCTCTGCCGCGGTGACTGCGGCGAT
GCACGGCGCCAGCGTCATGGTGGCGGAGAAAGCGTCAGTGCTCGGCGGAACCAGCGCCTGGTCCGGCGGCTGGCTGTGGA
TCCCCCGCAACCCGCTGGCGCGGGCGGAGGGCATCGACGAAGCAGCCGACGCGCCGCTGACCTATCTGCAGCATGAGATG
GGGGGCGAAGCCGCCGATATTCGTCTGCAAACCTTCCTGCGTTACGGGCCGGAGATGGTGGAATTTTTCCATCAGCGGAC
GGCGGTGCAGTTTCTCTCGGGCAGCGCCATGCCGGACTTTCACCCGTCGCCGGGTGCGGCGAACGGTGGGCGGTCGGTCA
CCGCGCAACCCTACGATGGCCGCCTGCTCGGCGACTGGCTCCATCGCCTGCGTCCGCCGCTGGAAACCATTAGCCTGGGC
GGGATGGGCATCGCCGGCGGCGCGGATATGGCGCATTTTTTCAATGCCACCCGCTCGCCGCGCTCCGCGCTGTATGCTGC
CCGCCGCCTGCTGCGCCACGGCTGGCAGCGGCTACGCGCCGGACGGGGGCAGCATCTGGTCAATGGCAATGCGCTGGTCG
CCCGTCTGCTGCGATCCGCCCTCGACGCCGGCGTGCGTTTTCAGCTCAATGCCCCGGTGGTCCGGCTGCTGCAGGGTCCG
CCGGGCGTGTCCGGCGCGGTGTTGCGCAGCGACGGCGGGGAGATTCACGTCGAAGCTGGCGCCGTGGTGCTGGCCTGCGG
CGGTTTTCCCCACGATCGCCAGCGGCTGGCGCAGGTGGTGCCCCACGCGGCGGAGGGTTACGGCCATTTCTCCGCCGCAC
CGCCGGACAATCAGGGCGAGGGGATCAGGCTTGGCGAATCCGTCGGCGGCCAGTTCAACACTTCCCTGCGCCACCCGCTG
GCCTGGGCGCCGGTGTCCCGCGTCACTCTGGCCAGCGGCCAGCAGCTAATGTTTCCTCATCTGGTGGAGCGCGCCAAACC
CGGGGTGATCGCCGTTCTGCCCAACGGCAAACGTTTTGTTAACGAGGCCGACTCTTATCATGACTTTATCGCCGCCCTGC
TGGCGGCCACACCCGCGGGCGACACGCCACAGGCGTGGCTGCTGGCCGATCGTCGTACGCTGCGTCGCTACGGCCTGGGC
CACGCCAGACCGTTCCCGTTCCCCCCCACCGCCTGGCTGCGTACCGGCTATCTGCAGCGAGGAAACACCCTGGCGGAGCT
GGCGAAGCAGTGCGCTATCGACGCCAATGCGCTGGCGGAAACCGTTGAACGCTTTAACCACTTCGCCAGCGCTGGCGAAG
ACGTCGATTTTCACCGCGGGGCATCAGCCTATAACCGCGCCCAGGGTGACCATCAGGTGACGCTCGGACCGCTGCGCGAA
GGGCCGTTCTACGCGGTGCGCATTCTGCCCGGCTCGCTGGGCACCTTCAGCGGATTGCAAACCGACGAACACGCCCGGGT
GCTGGATGAACAGCAGCAGCCGATACCGGGTCTGTACGCCATCGGCAACGACATGTCGAGCGTGATGCGCGGCTATTACC
CCAGCGGAGGGATCACCCTCGGGCCCGCCATGACCTTCGGCTATCTGGTGGGTAAAAACCTGGCAAAAAAAACAAATATA
AACAATAACATAGTTTGA

Upstream 100 bases:

>100_bases
ACCTTCTCGCGTAAAAATCGCGAACTGGCCGCCGTGGAACGCCTCGAGTCGGTGCTGATGCGCCCCACCGCTTTTTCACC
TCTGCAGTAAGGAGTCCAAC

Downstream 100 bases:

>100_bases
TTTCCACGAATGGATGCACCCTAACTCTCTTCACCTGCAACTGTACCGGAGCCCTTTATGAACAAGCGTACCCTATCGCT
CGCCGCGCTGACCCTGCTCG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MSGPVKVDVLVVGSGAAGLSAAVTAAMHGASVMVAEKASVLGGTSAWSGGWLWIPRNPLARAEGIDEAADAPLTYLQHEM
GGEAADIRLQTFLRYGPEMVEFFHQRTAVQFLSGSAMPDFHPSPGAANGGRSVTAQPYDGRLLGDWLHRLRPPLETISLG
GMGIAGGADMAHFFNATRSPRSALYAARRLLRHGWQRLRAGRGQHLVNGNALVARLLRSALDAGVRFQLNAPVVRLLQGP
PGVSGAVLRSDGGEIHVEAGAVVLACGGFPHDRQRLAQVVPHAAEGYGHFSAAPPDNQGEGIRLGESVGGQFNTSLRHPL
AWAPVSRVTLASGQQLMFPHLVERAKPGVIAVLPNGKRFVNEADSYHDFIAALLAATPAGDTPQAWLLADRRTLRRYGLG
HARPFPFPPTAWLRTGYLQRGNTLAELAKQCAIDANALAETVERFNHFASAGEDVDFHRGASAYNRAQGDHQVTLGPLRE
GPFYAVRILPGSLGTFSGLQTDEHARVLDEQQQPIPGLYAIGNDMSSVMRGYYPSGGITLGPAMTFGYLVGKNLAKKTNI
NNNIV

Sequences:

>Translated_565_residues
MSGPVKVDVLVVGSGAAGLSAAVTAAMHGASVMVAEKASVLGGTSAWSGGWLWIPRNPLARAEGIDEAADAPLTYLQHEM
GGEAADIRLQTFLRYGPEMVEFFHQRTAVQFLSGSAMPDFHPSPGAANGGRSVTAQPYDGRLLGDWLHRLRPPLETISLG
GMGIAGGADMAHFFNATRSPRSALYAARRLLRHGWQRLRAGRGQHLVNGNALVARLLRSALDAGVRFQLNAPVVRLLQGP
PGVSGAVLRSDGGEIHVEAGAVVLACGGFPHDRQRLAQVVPHAAEGYGHFSAAPPDNQGEGIRLGESVGGQFNTSLRHPL
AWAPVSRVTLASGQQLMFPHLVERAKPGVIAVLPNGKRFVNEADSYHDFIAALLAATPAGDTPQAWLLADRRTLRRYGLG
HARPFPFPPTAWLRTGYLQRGNTLAELAKQCAIDANALAETVERFNHFASAGEDVDFHRGASAYNRAQGDHQVTLGPLRE
GPFYAVRILPGSLGTFSGLQTDEHARVLDEQQQPIPGLYAIGNDMSSVMRGYYPSGGITLGPAMTFGYLVGKNLAKKTNI
NNNIV
>Mature_564_residues
SGPVKVDVLVVGSGAAGLSAAVTAAMHGASVMVAEKASVLGGTSAWSGGWLWIPRNPLARAEGIDEAADAPLTYLQHEMG
GEAADIRLQTFLRYGPEMVEFFHQRTAVQFLSGSAMPDFHPSPGAANGGRSVTAQPYDGRLLGDWLHRLRPPLETISLGG
MGIAGGADMAHFFNATRSPRSALYAARRLLRHGWQRLRAGRGQHLVNGNALVARLLRSALDAGVRFQLNAPVVRLLQGPP
GVSGAVLRSDGGEIHVEAGAVVLACGGFPHDRQRLAQVVPHAAEGYGHFSAAPPDNQGEGIRLGESVGGQFNTSLRHPLA
WAPVSRVTLASGQQLMFPHLVERAKPGVIAVLPNGKRFVNEADSYHDFIAALLAATPAGDTPQAWLLADRRTLRRYGLGH
ARPFPFPPTAWLRTGYLQRGNTLAELAKQCAIDANALAETVERFNHFASAGEDVDFHRGASAYNRAQGDHQVTLGPLREG
PFYAVRILPGSLGTFSGLQTDEHARVLDEQQQPIPGLYAIGNDMSSVMRGYYPSGGITLGPAMTFGYLVGKNLAKKTNIN
NNIV

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 1,4- androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=339, Percent_Identity=25.3687315634218, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 60235; Mature: 60104

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPVKVDVLVVGSGAAGLSAAVTAAMHGASVMVAEKASVLGGTSAWSGGWLWIPRNPLA
CCCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCCCEEEECCCCCH
RAEGIDEAADAPLTYLQHEMGGEAADIRLQTFLRYGPEMVEFFHQRTAVQFLSGSAMPDF
HHCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCC
HPSPGAANGGRSVTAQPYDGRLLGDWLHRLRPPLETISLGGMGIAGGADMAHFFNATRSP
CCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHEECCCCCCCCCCHHHHHHHCCCCH
RSALYAARRLLRHGWQRLRAGRGQHLVNGNALVARLLRSALDAGVRFQLNAPVVRLLQGP
HHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCCEEEECCHHHHHHCCC
PGVSGAVLRSDGGEIHVEAGAVVLACGGFPHDRQRLAQVVPHAAEGYGHFSAAPPDNQGE
CCCCCEEEECCCCEEEEECCEEEEEECCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCC
GIRLGESVGGQFNTSLRHPLAWAPVSRVTLASGQQLMFPHLVERAKPGVIAVLPNGKRFV
CEEECHHCCCCCCCCCCCCCEECCHHHEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHH
NEADSYHDFIAALLAATPAGDTPQAWLLADRRTLRRYGLGHARPFPFPPTAWLRTGYLQR
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHC
GNTLAELAKQCAIDANALAETVERFNHFASAGEDVDFHRGASAYNRAQGDHQVTLGPLRE
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHCCCCCEEEECCCCC
GPFYAVRILPGSLGTFSGLQTDEHARVLDEQQQPIPGLYAIGNDMSSVMRGYYPSGGITL
CCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCCCEEE
GPAMTFGYLVGKNLAKKTNINNNIV
CHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SGPVKVDVLVVGSGAAGLSAAVTAAMHGASVMVAEKASVLGGTSAWSGGWLWIPRNPLA
CCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCCCEEEECCCCCH
RAEGIDEAADAPLTYLQHEMGGEAADIRLQTFLRYGPEMVEFFHQRTAVQFLSGSAMPDF
HHCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCC
HPSPGAANGGRSVTAQPYDGRLLGDWLHRLRPPLETISLGGMGIAGGADMAHFFNATRSP
CCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHEECCCCCCCCCCHHHHHHHCCCCH
RSALYAARRLLRHGWQRLRAGRGQHLVNGNALVARLLRSALDAGVRFQLNAPVVRLLQGP
HHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCCEEEECCHHHHHHCCC
PGVSGAVLRSDGGEIHVEAGAVVLACGGFPHDRQRLAQVVPHAAEGYGHFSAAPPDNQGE
CCCCCEEEECCCCEEEEECCEEEEEECCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCC
GIRLGESVGGQFNTSLRHPLAWAPVSRVTLASGQQLMFPHLVERAKPGVIAVLPNGKRFV
CEEECHHCCCCCCCCCCCCCEECCHHHEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHH
NEADSYHDFIAALLAATPAGDTPQAWLLADRRTLRRYGLGHARPFPFPPTAWLRTGYLQR
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHC
GNTLAELAKQCAIDANALAETVERFNHFASAGEDVDFHRGASAYNRAQGDHQVTLGPLRE
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHCCCCCEEEECCCCC
GPFYAVRILPGSLGTFSGLQTDEHARVLDEQQQPIPGLYAIGNDMSSVMRGYYPSGGITL
CCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCCCEEE
GPAMTFGYLVGKNLAKKTNINNNIV
CHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA