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The map label for this gene is ulaC [H]

Identifier: 238893336

GI number: 238893336

Start: 1180057

End: 1180500

Strand: Reverse

Name: ulaC [H]

Synonym: KP1_1215

Alternate gene names: 238893336

Gene position: 1180500-1180057 (Counterclockwise)

Preceding gene: 238893337

Following gene: 238893335

Centisome position: 22.49

GC content: 50.23

Gene sequence:

>444_bases
ATGGAAATTATTTTTGACCCGTCGTTAATCGCCCTTAAGCAGAATATTTCCCGTGCGGAAGAGGCCATCGAACTGGCGGG
TTCATTACTTGCCAGGCGCCAGATTTGCAGCGCCGAATATGTCAACGAGATGCTGACGGTATATGAAGATTTTGGCGCCG
CCATCGTGATAGATGACGGGATTGCCATGCCGCATGCCCGGCCGGAAAAAGGGGCATTACAGACCGGGTTCTCACTTGTC
ACCACCGCCACGCCAATCTCCTTCGGCCACGATGAGTTCGATCCGGTTTCCCTGGTCATCGCGATCGCCGGCGCCGATGC
TGACAGTCATATCAAAATGATCCAACTGATAGCCTCGCTGATCGAGTCAGATATTGTGACCTTTCTTCAGCAGGAAAATG
ACGTTAATTCAGTCTTACATTTCATTCAAAAACAAATGGAGTAG

Upstream 100 bases:

>100_bases
ATCAATATTTAAAACCGCGGATGTGATCTCATCCATCATTTTCATCAATGTATTTGGTCATGATTTAACTCAGGAACAGG
AATACGTTCAGGAGCTGAGG

Downstream 100 bases:

>100_bases
TCATTATGTTAGTTATCAGAACGGTTTGTGGTAACGGTATTGGCAGCTCATTGATGGCTGCGAATAATGTGAAAAAGATT
TGTGACGAATTAGGTATCAA

Product: putative phosphoenolpyruvate-dependent sugar PTS family enzyme IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: PTS system ascorbate-specific EIIA component [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MEIIFDPSLIALKQNISRAEEAIELAGSLLARRQICSAEYVNEMLTVYEDFGAAIVIDDGIAMPHARPEKGALQTGFSLV
TTATPISFGHDEFDPVSLVIAIAGADADSHIKMIQLIASLIESDIVTFLQQENDVNSVLHFIQKQME

Sequences:

>Translated_147_residues
MEIIFDPSLIALKQNISRAEEAIELAGSLLARRQICSAEYVNEMLTVYEDFGAAIVIDDGIAMPHARPEKGALQTGFSLV
TTATPISFGHDEFDPVSLVIAIAGADADSHIKMIQLIASLIESDIVTFLQQENDVNSVLHFIQKQME
>Mature_147_residues
MEIIFDPSLIALKQNISRAEEAIELAGSLLARRQICSAEYVNEMLTVYEDFGAAIVIDDGIAMPHARPEKGALQTGFSLV
TTATPISFGHDEFDPVSLVIAIAGADADSHIKMIQLIASLIESDIVTFLQQENDVNSVLHFIQKQME

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367359, Length=116, Percent_Identity=38.7931034482759, Blast_Score=87, Evalue=4e-19,
Organism=Escherichia coli, GI1790755, Length=121, Percent_Identity=34.7107438016529, Blast_Score=83, Evalue=6e-18,
Organism=Escherichia coli, GI1789302, Length=112, Percent_Identity=37.5, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 16060; Mature: 16060

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIFDPSLIALKQNISRAEEAIELAGSLLARRQICSAEYVNEMLTVYEDFGAAIVIDDG
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
IAMPHARPEKGALQTGFSLVTTATPISFGHDEFDPVSLVIAIAGADADSHIKMIQLIASL
CCCCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
IESDIVTFLQQENDVNSVLHFIQKQME
HHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEIIFDPSLIALKQNISRAEEAIELAGSLLARRQICSAEYVNEMLTVYEDFGAAIVIDDG
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
IAMPHARPEKGALQTGFSLVTTATPISFGHDEFDPVSLVIAIAGADADSHIKMIQLIASL
CCCCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
IESDIVTFLQQENDVNSVLHFIQKQME
HHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]