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The map label for this gene is yafC [H]

Identifier: 238893200

GI number: 238893200

Start: 1042381

End: 1043286

Strand: Reverse

Name: yafC [H]

Synonym: KP1_1066

Alternate gene names: 238893200

Gene position: 1043286-1042381 (Counterclockwise)

Preceding gene: 238893204

Following gene: 238893196

Centisome position: 19.88

GC content: 58.61

Gene sequence:

>906_bases
ATGAGAGCCACATCAGAGGAGATCGCCATCTTTGTGGCGGTGGTGGAAAGCGGGAGTTTCAGCCGGGCGGCCGAGCAGCT
CGGACAGGCCAACTCCGCCGTCAGCCGGGCGGTCAAAAAGCTGGAATCAAAGCTAGGCGTAAGCCTGCTCAATCGGACCA
CCCGCCAGCTCAGCCTGACAGAAGAAGGCGAGCGCTATTTTCGCCGGATGCAGGTGGTCTTGCAGGAAATGGCGGCGGCA
GAGAACGATCTGCTGGAGACGCGCACGACGCCGCGGGGCCTGCTGCGGGTTGATGCCGCGACGCCGGTGATGCTGCATTT
TCTCATGCCGCTGGTGAAGCCATTTCGCGAGCGCTACCCGGAAATGACGCTGTCGCTCGTCTCGTCTGAGACGTTTATCA
ATCTGATTGAACGGAAAGTGGATGTGGCCATTCGGGCCGGGACCTTAACGGATTCCAGCCTGCGCGCCCGACCGCTGTTT
ACCAGCTATCGTAAGATCGTCGCCTCGCCCGACTATGTCGCGCGCTACGGTATGCCGCAGCATCCATCCGATCTGAAACA
GCATCACTGCCTCGGCTTCACCGAGCCGGTATCGCTGAATACCTGGCCGGTCTCCTGTTGCGATGGCCAGCTGTTAGAGA
TCGAAGCGGCGGTGTCATCCAATAGCGGCGAAACGCTCAAGCAGCTGTGCCTGACCGGCAACGGTATTGCCTGCCTGTCG
GATTACATGGTGGATAAAGAGATTGCCAGCGGAGAGTTTGTCGAGCTACTGGCGGATAAGCGCTTACCGGTGGAAATGCC
TTTCAGTGCCGTCTATTACAGCGACCGGGCGGTCAGCACTCACATCAGGGCATTTATTGATTTTCTGAGCGACCACGTAA
AACAGCTCCCGAAGGAGCTGTCGTAA

Upstream 100 bases:

>100_bases
TACTCCGTAGCATCAGGATTAAGATGACACGTAGTATGAAGGGTTGTATAAATAACAAAAACTATCAAAGTATCAATAGA
ATTTTGCTATAGGTGCAATA

Downstream 100 bases:

>100_bases
TACCATCTCGGTCTGCAAGGCGAACGGCATACCGGTAGCGAGTGATTAATCCCACTGCGGCGCCAGACCTTCCGGGCTCA
CCAGCCGATCGTTGCAATCC

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MRATSEEIAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLESKLGVSLLNRTTRQLSLTEEGERYFRRMQVVLQEMAAA
ENDLLETRTTPRGLLRVDAATPVMLHFLMPLVKPFRERYPEMTLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
TSYRKIVASPDYVARYGMPQHPSDLKQHHCLGFTEPVSLNTWPVSCCDGQLLEIEAAVSSNSGETLKQLCLTGNGIACLS
DYMVDKEIASGEFVELLADKRLPVEMPFSAVYYSDRAVSTHIRAFIDFLSDHVKQLPKELS

Sequences:

>Translated_301_residues
MRATSEEIAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLESKLGVSLLNRTTRQLSLTEEGERYFRRMQVVLQEMAAA
ENDLLETRTTPRGLLRVDAATPVMLHFLMPLVKPFRERYPEMTLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
TSYRKIVASPDYVARYGMPQHPSDLKQHHCLGFTEPVSLNTWPVSCCDGQLLEIEAAVSSNSGETLKQLCLTGNGIACLS
DYMVDKEIASGEFVELLADKRLPVEMPFSAVYYSDRAVSTHIRAFIDFLSDHVKQLPKELS
>Mature_301_residues
MRATSEEIAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLESKLGVSLLNRTTRQLSLTEEGERYFRRMQVVLQEMAAA
ENDLLETRTTPRGLLRVDAATPVMLHFLMPLVKPFRERYPEMTLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
TSYRKIVASPDYVARYGMPQHPSDLKQHHCLGFTEPVSLNTWPVSCCDGQLLEIEAAVSSNSGETLKQLCLTGNGIACLS
DYMVDKEIASGEFVELLADKRLPVEMPFSAVYYSDRAVSTHIRAFIDFLSDHVKQLPKELS

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=83.8383838383838, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=32.9861111111111, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=30.0675675675676, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=29.8969072164948, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=31.1864406779661, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=28.135593220339, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=28.7671232876712, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789173, Length=245, Percent_Identity=28.9795918367347, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI157672245, Length=200, Percent_Identity=33.5, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082132, Length=303, Percent_Identity=27.3927392739274, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788706, Length=298, Percent_Identity=25.503355704698, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=23.1543624161074, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786448, Length=254, Percent_Identity=25.9842519685039, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=126, Percent_Identity=34.1269841269841, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=154, Percent_Identity=29.2207792207792, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786508, Length=263, Percent_Identity=26.9961977186312, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=311, Percent_Identity=22.8295819935691, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789492, Length=261, Percent_Identity=26.0536398467433, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33536; Mature: 33536

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATSEEIAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLESKLGVSLLNRTTRQLSLT
CCCCHHHHEEEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EEGERYFRRMQVVLQEMAAAENDLLETRTTPRGLLRVDAATPVMLHFLMPLVKPFRERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCH
EMTLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLFTSYRKIVASPDYVARYGMPQ
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCC
HPSDLKQHHCLGFTEPVSLNTWPVSCCDGQLLEIEAAVSSNSGETLKQLCLTGNGIACLS
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCHHHHHHHHCCCCHHHHH
DYMVDKEIASGEFVELLADKRLPVEMPFSAVYYSDRAVSTHIRAFIDFLSDHVKQLPKEL
HHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHC
S
C
>Mature Secondary Structure
MRATSEEIAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLESKLGVSLLNRTTRQLSLT
CCCCHHHHEEEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EEGERYFRRMQVVLQEMAAAENDLLETRTTPRGLLRVDAATPVMLHFLMPLVKPFRERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCH
EMTLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLFTSYRKIVASPDYVARYGMPQ
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCC
HPSDLKQHHCLGFTEPVSLNTWPVSCCDGQLLEIEAAVSSNSGETLKQLCLTGNGIACLS
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCHHHHHHHHCCCCHHHHH
DYMVDKEIASGEFVELLADKRLPVEMPFSAVYYSDRAVSTHIRAFIDFLSDHVKQLPKEL
HHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]