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The map label for this gene is gmhB [H]

Identifier: 238893198

GI number: 238893198

Start: 1035223

End: 1035789

Strand: Direct

Name: gmhB [H]

Synonym: KP1_1061

Alternate gene names: 238893198

Gene position: 1035223-1035789 (Clockwise)

Preceding gene: 238893197

Following gene: 238893199

Centisome position: 19.72

GC content: 53.26

Gene sequence:

>567_bases
GTGGCAAAGTCAGTACCCGCAATTTTTCTCGACCGTGACGGCACTATTAATGTCGATCATGGCTACGTCCACGAAATCGA
CAATTTTGAATTTATCGATGGCGTCATTGACGCGATGCGCGAACTAAAAGAGATGGGCTACGCGCTGGTGCTGGTCACTA
ACCAGTCCGGTATTGCCCGCGGTAAATTTACCGAAGCCCAGTTTGAAACGCTGACCGAATGGATGGACTGGTCTCTGGCA
GACCGCGGCGTCGACCTCGACGGTATCTACTATTGCCCGCATCACCCGCAGGGTGCGGTTGAGGAGTACCGTCAGACCTG
TGATTGTCGTAAACCGCATCCGGGGATGCTGATTTCCGCCCGCGATTATCTGCATATCGATATGGCTGCTTCTTATATGG
TAGGGGACAAACTGGAAGATATGCAGGCGGCAGCGGCTGCGGATGTCGGGACTAAAGTACTGGTGCGCACCGGTAAACCC
CTGACTGAAGAAGCGGAAAAAGCGGCGGATTGGGTGCTAAATAGCCTGGCAGAGCTGCCGGCGGCGATTAAAAAGCAGCA
AAAATAA

Upstream 100 bases:

>100_bases
ATCCAGACGTCTAAATCAATCTGACTCTTTATAATGAGCACTTTCTTGCATGCGGAAACATGCGATACTAGCGGCACTAG
TCTTTTTCAGGAGCAAACCG

Downstream 100 bases:

>100_bases
GCGTTGCGTTTAAAAGATGAGCGGTTGAAATAAAATTGTATTTTTCCGCTTGTCATTCCCGGAGAGCTCCCTATAATGCG
CCTCCATCGACACGGCAGAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIARGKFTEAQFETLTEWMDWSLA
DRGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQAAAAADVGTKVLVRTGKP
LTEEAEKAADWVLNSLAELPAAIKKQQK

Sequences:

>Translated_188_residues
MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIARGKFTEAQFETLTEWMDWSLA
DRGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQAAAAADVGTKVLVRTGKP
LTEEAEKAADWVLNSLAELPAAIKKQQK
>Mature_187_residues
AKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIARGKFTEAQFETLTEWMDWSLAD
RGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQAAAAADVGTKVLVRTGKPL
TEEAEKAADWVLNSLAELPAAIKKQQK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=188, Percent_Identity=92.0212765957447, Blast_Score=369, Evalue=1e-104,
Organism=Escherichia coli, GI87082027, Length=140, Percent_Identity=33.5714285714286, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20949; Mature: 20818

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIAR
CCCCCCEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
GKFTEAQFETLTEWMDWSLADRGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISA
CCCCHHHHHHHHHHHCCHHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEC
RDYLHIDMAASYMVGDKLEDMQAAAAADVGTKVLVRTGKPLTEEAEKAADWVLNSLAELP
CCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
AAIKKQQK
HHHHHCCC
>Mature Secondary Structure 
AKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIAR
CCCCCEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
GKFTEAQFETLTEWMDWSLADRGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISA
CCCCHHHHHHHHHHHCCHHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEC
RDYLHIDMAASYMVGDKLEDMQAAAAADVGTKVLVRTGKPLTEEAEKAADWVLNSLAELP
CCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
AAIKKQQK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11108008; 11206551; 11258796 [H]