Click here to switch to the map view.

The map label for this gene is fabZ [H]

Identifier: 238893176

GI number: 238893176

Start: 1014452

End: 1014979

Strand: Direct

Name: fabZ [H]

Synonym: KP1_1036

Alternate gene names: 238893176

Gene position: 1014452-1014979 (Clockwise)

Preceding gene: 238893175

Following gene: 238893177

Centisome position: 19.33

GC content: 51.52

Gene sequence:

>528_bases
TTGCATTCGCTAAAAGATTGCCGCAGGCCGTGTTATTATTGCCTTTTAGTACATTTAGACAGGAAGAGTATTTTGACTAC
TGACACTCATACTCTGCACATTGAAGAGATTCTGGAACTTCTGCCTCACCGTTACCCGTTCCTGCTGGTAGACCGCGTGC
TGGATTTTGAAGAAGGTCGTTTTCTGCGCGCAGTAAAAAATGTTTCTGTAAACGAGCCGTTTTTCCAGGGGCACTTCCCT
GGTAAGCCGATTTTGCCGGGCGTCCTGATTCTGGAAGCAATGGCGCAAGCCACCGGGATTCTGGCGTTCAAAAGCGTCGG
AAAACTGGAACCAGGCGAGCTGTACTACTTCGCGGGTATCGATGAAGCACGCTTCAAACGCCCGGTAGTACCAGGCGATC
AGATGATTATGGAAGTCACTTTCGAGAAAACCCGCCGCGGCCTGACCCGTTTCAAAGGCGTTGCGCTGGTTGACGGTAAA
GTGGTTTGCGAAGCGACGATGATGTGTGCGCGTAGCCGGGAGGCCTGA

Upstream 100 bases:

>100_bases
GATGAATATTGACGAGATGAGCAAGCGCCTGAAAGCGATTGAGCGCAAGGTTAATCAACAAGACTAATTCATCATTTGGT
CACATGACATTTCCGGCCTG

Downstream 100 bases:

>100_bases
TACGTGATTGATAAAACCGCTTTTGTTCATCCTACCGCCATTGTAGAAGAAGGCGCCGTGATTGGCGCTAACGTCCACAT
TGGTCCGTTTTGTATTGTTG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MHSLKDCRRPCYYCLLVHLDRKSILTTDTHTLHIEEILELLPHRYPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFP
GKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGK
VVCEATMMCARSREA

Sequences:

>Translated_175_residues
MHSLKDCRRPCYYCLLVHLDRKSILTTDTHTLHIEEILELLPHRYPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFP
GKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGK
VVCEATMMCARSREA
>Mature_175_residues
MHSLKDCRRPCYYCLLVHLDRKSILTTDTHTLHIEEILELLPHRYPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFP
GKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGK
VVCEATMMCARSREA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=151, Percent_Identity=96.6887417218543, Blast_Score=300, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 19940; Mature: 19940

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSLKDCRRPCYYCLLVHLDRKSILTTDTHTLHIEEILELLPHRYPFLLVDRVLDFEEGR
CCCHHHHHHHHHHHHHEEECCCCEEECCCCEEEHHHHHHHCCCCCCHHHHHHHHCCCCCH
FLRAVKNVSVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGI
HHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHSLKDCRRPCYYCLLVHLDRKSILTTDTHTLHIEEILELLPHRYPFLLVDRVLDFEEGR
CCCHHHHHHHHHHHHHEEECCCCEEECCCCEEEHHHHHHHCCCCCCHHHHHHHHCCCCCH
FLRAVKNVSVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGI
HHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA