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The map label for this gene is insK [H]

Identifier: 238893143

GI number: 238893143

Start: 975738

End: 976523

Strand: Direct

Name: insK [H]

Synonym: KP1_0996

Alternate gene names: 238893143

Gene position: 975738-976523 (Clockwise)

Preceding gene: 238893142

Following gene: 238893144

Centisome position: 18.59

GC content: 51.02

Gene sequence:

>786_bases
ATGTCCCGTAGCACGTGGTATTACAATATGAATGCACTGAAGCAAGGGGACAGGTATGCGGGTCTTAAAGAGAACATCAG
GAAGATATACCACTATCACAAAGGTCGTTATGGCTACCGCAGGATCACGCTCGCACTGAGAAAACAGGGGCTGCGGATAA
ACCATAAAACAGTGCAGCGGCTGATGGCAGAACTGTCACTCCGGTCTGTGATAAGGGCGAAAAAATATCGTGCCTGGAAA
GGGAGAACGGGCGAGGCCGCGCCCAATATCCTGAGCCGGAACTTCGGTGCGTCAAAAGCCAACGAAAAATGGGTAACAGA
TGTGACAGAGTTCCCGGTACAGGGAAAAAAGCTTTACCTGTCGTCAGTTCTCGATCTGTTTAACCGGGAGGTTATCGCCT
ACAGCCTGTCGGAAAGGCCGGTGATGGAGATGGTGAATACGATGCTGGACGGTGCGTTCCCGAAGCTCAGACCGGGAGAT
GCTCCGCTGCTGCACTCGGATCAGGGCTGGCATTACAGGATGAGGAGCTATCAGGAACGTTTAAAGGCGCATGGGATGAC
GCAGAGTATGTCGCGTAAAGGAAACTGCCTGGATAATGCAGTGATGGAAAACTTCTTCGGGACCCTGAAATCGGAGTGTT
TTTATCTGAGGGAGTTCAGGAGTGTCAGTGCGCTAAGAAAAGCCGTAGAGGACTATATCCATTACTACAACAACGAGCGG
ATAAGCCTGAAATTAAAAGGCCTGAGTCCGGTAGAGTACCGAACCCAGGCTCTGAGAGCCGCTTAA

Upstream 100 bases:

>100_bases
TGAAAGCCTTGGTTCAGAGCGAAAAAAATGGCAAAAAGCCCTGATAATCAGTGAACTAAGGCATGAACACGCTCTGCGGG
ACCTTCTGCGGGCGGCCGGT

Downstream 100 bases:

>100_bases
TATGAACCATCCAACTTTATGGGGTCAGTCCAGTAGCGCCGCCGGGCAATTCCTGAAGATTGCACTTTGTCAGCAGTCTG
GGGCATCCGTAAGGGCGCCT

Product: orfB of ISKpn1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSRSTWYYNMNALKQGDRYAGLKENIRKIYHYHKGRYGYRRITLALRKQGLRINHKTVQRLMAELSLRSVIRAKKYRAWK
GRTGEAAPNILSRNFGASKANEKWVTDVTEFPVQGKKLYLSSVLDLFNREVIAYSLSERPVMEMVNTMLDGAFPKLRPGD
APLLHSDQGWHYRMRSYQERLKAHGMTQSMSRKGNCLDNAVMENFFGTLKSECFYLREFRSVSALRKAVEDYIHYYNNER
ISLKLKGLSPVEYRTQALRAA

Sequences:

>Translated_261_residues
MSRSTWYYNMNALKQGDRYAGLKENIRKIYHYHKGRYGYRRITLALRKQGLRINHKTVQRLMAELSLRSVIRAKKYRAWK
GRTGEAAPNILSRNFGASKANEKWVTDVTEFPVQGKKLYLSSVLDLFNREVIAYSLSERPVMEMVNTMLDGAFPKLRPGD
APLLHSDQGWHYRMRSYQERLKAHGMTQSMSRKGNCLDNAVMENFFGTLKSECFYLREFRSVSALRKAVEDYIHYYNNER
ISLKLKGLSPVEYRTQALRAA
>Mature_260_residues
SRSTWYYNMNALKQGDRYAGLKENIRKIYHYHKGRYGYRRITLALRKQGLRINHKTVQRLMAELSLRSVIRAKKYRAWKG
RTGEAAPNILSRNFGASKANEKWVTDVTEFPVQGKKLYLSSVLDLFNREVIAYSLSERPVMEMVNTMLDGAFPKLRPGDA
PLLHSDQGWHYRMRSYQERLKAHGMTQSMSRKGNCLDNAVMENFFGTLKSECFYLREFRSVSALRKAVEDYIHYYNNERI
SLKLKGLSPVEYRTQALRAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=209, Percent_Identity=30.1435406698565, Blast_Score=101, Evalue=6e-22,
Organism=Escherichia coli, GI1789981, Length=257, Percent_Identity=64.591439688716, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1788405, Length=231, Percent_Identity=35.9307359307359, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787263, Length=231, Percent_Identity=35.9307359307359, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786753, Length=231, Percent_Identity=35.9307359307359, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786570, Length=231, Percent_Identity=35.9307359307359, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786490, Length=231, Percent_Identity=35.9307359307359, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30496; Mature: 30364

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSTWYYNMNALKQGDRYAGLKENIRKIYHYHKGRYGYRRITLALRKQGLRINHKTVQR
CCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHH
LMAELSLRSVIRAKKYRAWKGRTGEAAPNILSRNFGASKANEKWVTDVTEFPVQGKKLYL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHH
SSVLDLFNREVIAYSLSERPVMEMVNTMLDGAFPKLRPGDAPLLHSDQGWHYRMRSYQER
HHHHHHHCCHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
LKAHGMTQSMSRKGNCLDNAVMENFFGTLKSECFYLREFRSVSALRKAVEDYIHYYNNER
HHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
ISLKLKGLSPVEYRTQALRAA
EEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SRSTWYYNMNALKQGDRYAGLKENIRKIYHYHKGRYGYRRITLALRKQGLRINHKTVQR
CCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHH
LMAELSLRSVIRAKKYRAWKGRTGEAAPNILSRNFGASKANEKWVTDVTEFPVQGKKLYL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHH
SSVLDLFNREVIAYSLSERPVMEMVNTMLDGAFPKLRPGDAPLLHSDQGWHYRMRSYQER
HHHHHHHCCHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
LKAHGMTQSMSRKGNCLDNAVMENFFGTLKSECFYLREFRSVSALRKAVEDYIHYYNNER
HHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
ISLKLKGLSPVEYRTQALRAA
EEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]