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The map label for this gene is yjbC [H]

Identifier: 238892493

GI number: 238892493

Start: 276978

End: 277853

Strand: Direct

Name: yjbC [H]

Synonym: KP1_0260

Alternate gene names: 238892493

Gene position: 276978-277853 (Clockwise)

Preceding gene: 238892491

Following gene: 238892497

Centisome position: 5.28

GC content: 54.68

Gene sequence:

>876_bases
ATGCTGCCCGACTCATCAACCCGATTAAACAAATACATCAGTGAAAGCGGCATCTGCTCGCGTCGCGAAGCGGACCGCTT
TATTGAACAAGGCAACGTCTTTATCAATGGCAAGCGCGCCACGATTGGCGATCAGGTGAAGCCTGGCGATTTAGTCAAAG
TGAACGGACGGTTGATTGAGCCGCGCGAAGCGGATGATCTGGTACTGATTGCGCTGAATAAGCCGGTCGGCATTGTGAGC
ACCACGGAAGACGGCGAGCGCGACAACATTGTCGATTTCGTCAACCACAGCAAGCGTATCTTCCCTATTGGCCGTCTGGA
TAAAGATTCTCAGGGGCTGATCTTCCTCACCAACCACGGCGATCTGGTGAACAAGATCCTGCGCGCCGGCAACGACCATG
AAAAAGAGTATCTGGTGACGGTCGATAAGCCGGTGACCGATGAGTTCATTCGCGGCATGGGCGCGGGGGTACCGATTCTC
GGGACCGTGACCAAAAAATGTAAGGTAAAGAAAGAAGCGCCGTTCGTTTTCCGCATCACTCTGGTGCAGGGGCTGAATCG
CCAGATCCGTCGTATGTGCGAGCACTTTGGCTATGAAGTGACGAAGCTTGAGCGTACGCGGATCATGAACGTGAGCCTGA
CGGGGATCCCCTTGGGTGAATGGCGTGATCTAACCGATGACGAGCTGATCGACCTGTTCAAGCTGATTGAAAACTCCTCT
TCCGAAGCGAAGCCGAAAGCCAGGCCGAAGGCCAAAGCGGCGACTCCCGGCATCAAGCGCCCGGTGGTGAAGATGGAAAA
TAGCAACGATAAGGGCCGCCCGGCTGGTAACGGGAAACGTTTCACCCAGCCGGGACGTAAAAAGAAAGGGCGTTAA

Upstream 100 bases:

>100_bases
CTGTTCACAAGCCCGACGAAGCTTCTGGATAATGAATCACACAATCCAGGTTTTTTCTCGCCCACAAGGTAGGGTATATT
TCGCTTTTACAGGAGAATCT

Downstream 100 bases:

>100_bases
CGCCTGCCGCGGGTCGGCGTATTCGCCGACCAGGAAAAGGTCGCTTCCTTATCCGTTTTATAAGCCTGCTGTTTTCTCAC
CTGGCGGGCTTTCTTCGCTT

Product: 23S rRNA pseudouridine synthase F

Products: NA

Alternate protein names: rRNA pseudouridylate synthase F; rRNA-uridine isomerase F [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MLPDSSTRLNKYISESGICSRREADRFIEQGNVFINGKRATIGDQVKPGDLVKVNGRLIEPREADDLVLIALNKPVGIVS
TTEDGERDNIVDFVNHSKRIFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPVTDEFIRGMGAGVPIL
GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVTKLERTRIMNVSLTGIPLGEWRDLTDDELIDLFKLIENSS
SEAKPKARPKAKAATPGIKRPVVKMENSNDKGRPAGNGKRFTQPGRKKKGR

Sequences:

>Translated_291_residues
MLPDSSTRLNKYISESGICSRREADRFIEQGNVFINGKRATIGDQVKPGDLVKVNGRLIEPREADDLVLIALNKPVGIVS
TTEDGERDNIVDFVNHSKRIFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPVTDEFIRGMGAGVPIL
GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVTKLERTRIMNVSLTGIPLGEWRDLTDDELIDLFKLIENSS
SEAKPKARPKAKAATPGIKRPVVKMENSNDKGRPAGNGKRFTQPGRKKKGR
>Mature_291_residues
MLPDSSTRLNKYISESGICSRREADRFIEQGNVFINGKRATIGDQVKPGDLVKVNGRLIEPREADDLVLIALNKPVGIVS
TTEDGERDNIVDFVNHSKRIFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPVTDEFIRGMGAGVPIL
GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVTKLERTRIMNVSLTGIPLGEWRDLTDDELIDLFKLIENSS
SEAKPKARPKAKAATPGIKRPVVKMENSNDKGRPAGNGKRFTQPGRKKKGR

Specific function: Responsible for synthesis of pseudouridine from uracil- 2604 in 23S ribosomal RNA [H]

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790453, Length=292, Percent_Identity=91.4383561643836, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1787524, Length=287, Percent_Identity=32.404181184669, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1788510, Length=228, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081838, Length=178, Percent_Identity=29.7752808988764, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 32557; Mature: 32557

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDSSTRLNKYISESGICSRREADRFIEQGNVFINGKRATIGDQVKPGDLVKVNGRLIE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCEEEC
PREADDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRIFPIGRLDKDSQGLIFLTNHG
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCEEEEECCC
DLVNKILRAGNDHEKEYLVTVDKPVTDEFIRGMGAGVPILGTVTKKCKVKKEAPFVFRIT
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEH
LVQGLNRQIRRMCEHFGYEVTKLERTRIMNVSLTGIPLGEWRDLTDDELIDLFKLIENSS
HHHHCCHHHHHHHHHHCCEEEEEHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
SEAKPKARPKAKAATPGIKRPVVKMENSNDKGRPAGNGKRFTQPGRKKKGR
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLPDSSTRLNKYISESGICSRREADRFIEQGNVFINGKRATIGDQVKPGDLVKVNGRLIE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCEEEC
PREADDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRIFPIGRLDKDSQGLIFLTNHG
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCEEEEECCC
DLVNKILRAGNDHEKEYLVTVDKPVTDEFIRGMGAGVPILGTVTKKCKVKKEAPFVFRIT
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEH
LVQGLNRQIRRMCEHFGYEVTKLERTRIMNVSLTGIPLGEWRDLTDDELIDLFKLIENSS
HHHHCCHHHHHHHHHHCCEEEEEHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
SEAKPKARPKAKAATPGIKRPVVKMENSNDKGRPAGNGKRFTQPGRKKKGR
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]