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The map label for this gene is rpoB [H]

Identifier: 238892457

GI number: 238892457

Start: 227215

End: 231276

Strand: Direct

Name: rpoB [H]

Synonym: KP1_0222

Alternate gene names: 238892457

Gene position: 227215-231276 (Clockwise)

Preceding gene: 238892456

Following gene: 238892458

Centisome position: 4.33

GC content: 53.87

Gene sequence:

>4062_bases
ATGGGTCGACTTGTCAGCGAGCTGAGGAACCCTATGGTTTACTCCTATACCGAGAAAAAACGTATTCGTAAGGATTTTGG
TAAACGTCCACAAGTTCTGGATGTGCCATATCTCCTTTCTATCCAGCTTGACTCGTTCCAGAAGTTTATCGAGCAAGATC
CTGAAGGGCAGTATGGTCTGGAAGCTGCTTTCCGTTCCGTATTCCCGATTCAGAGCTACAGCGGTAATTCCGAGCTGCAA
TACGTCAGCTACCGTCTGGGCGAACCGGTTTTTGACGTTAAAGAATGTCAGATCCGTGGCGTGACTTATTCTGCACCGCT
GCGCGTAAAACTGCGTCTGGTGATCTACGAGCGCGAAGCGCCAGAAGGCACCGTCAAAGACATTAAAGAACAAGAAGTCT
ACATGGGCGAAATTCCGCTCATGACCGACAACGGTACCTTTGTTATCAACGGTACCGAGCGTGTTATCGTTTCTCAGCTG
CACCGTAGCCCGGGCGTCTTCTTTGACAGTGACAAAGGTAAGACCCACTCCTCCGGTAAGGTTCTGTATAACGCACGTAT
CATCCCTTACCGCGGTTCCTGGCTGGACTTCGAATTCGACCCGAAAGACAACCTGTTCGTTCGTATCGACCGTCGTCGTA
AGCTGCCGGCTACCATCATCCTGCGCGCGCTGAATTACACCACTGAGCAGATCCTTGACCTGTTCTTCGAAAAAGTGGTC
TTTGAAATTCGCGACAACAAGCTGCAGATGGAGCTGATTCCGGAGCGTCTGCGCGGTGAAACTGCCTCCTTCGATATCGA
AGCCAATGGCAAAGTGTACGTTGAGAAAGGCCGTCGCATCACGGCTCGTCATATCCGTCAGCTGGAAAAAGACGATATCA
AGCATATCGAAGTGCCGGTTGAATATATCGCGGGCAAAGTGGCGGCTAAAGACTATATCGATGAAGCGACTGGCGAACTG
ATCTGCCCGGCGAACATGGAGCTGAGCCTGGATCTGCTGGCTAAGCTGAGCCAGTCTGGCCACAAGCGTATCGAAACGCT
GTTCACCAACGATCTGGACCACGGCCCGTACATCTCTGAAACGGTACGCGTCGACCCGACTAACGATCGTCTGAGCGCGC
TGGTAGAAATCTACCGCATGATGCGCCCTGGCGAGCCGCCGACTCGTGAAGCCGCTGAAAGTCTGTTTGAGAACCTGTTC
TTCTCTGAAGACCGCTACGATCTGTCCGCGGTTGGTCGTATGAAGTTCAACCGTTCTCTGCTGCGCGACGAAATCGAAGG
TTCCGGTATCCTGAGCAAAGACGACATCATCGAAGTGATGAAGAAGCTCATCGATATCCGTAACGGTAAAGGCGAAGTGG
ACGATATCGACCACCTCGGCAACCGTCGTATCCGTTCCGTTGGCGAAATGGCGGAAAACCAGTTCCGCGTTGGCCTGGTA
CGTGTAGAGCGTGCGGTGAAAGAGCGTCTGTCTCTTGGCGATCTGGATACCCTGATGCCTCAGGATATGATCAACGCCAA
GCCGATTTCCGCAGCAGTGAAAGAGTTCTTTGGTTCCAGCCAGCTGTCTCAGTTTATGGACCAGAACAACCCGCTGTCTG
AGATTACGCACAAACGTCGTATCTCCGCACTCGGCCCAGGCGGTCTGACCCGTGAGCGCGCAGGCTTCGAAGTTCGAGAC
GTACACCCGACCCACTACGGTCGCGTATGTCCGATCGAAACGCCTGAAGGTCCGAACATCGGTCTGATTAACTCCCTGTC
CGTGTACGCGCAGACCAACGAATATGGCTTCCTTGAGACGCCGTATCGTAAAGTGACCGACGGTGTGGTTACTGACGAAA
TTCACTACCTGTCTGCTATCGAAGAAGGCAACTACGTTATCGCTCAGGCGAACTCCAACCTGGATGAAAACGGCCACTTC
GTAGAAGATCTGGTTACCTGCCGTAGCAAAGGCGAATCCAGCTTGTTCAGCCGCGACCAGGTTGACTACATGGACGTATC
CACCCAGCAGGTGGTATCCGTCGGTGCGTCCCTGATCCCGTTCCTGGAACACGATGACGCCAACCGTGCATTGATGGGTG
CGAACATGCAACGTCAGGCGGTTCCGACTCTGCGCGCTGATAAGCCGCTGGTTGGTACCGGTATGGAACGTGCTGTTGCC
GTTGACTCCGGTGTTACTGCCGTGGCTAAACGTGGCGGTACCGTTCAGTACGTGGATGCTTCCCGTATCGTTATCAAAGT
TAACGAAGACGAGATGTACCCGGGCGAAGCAGGTATCGACATCTATAACCTGACCAAGTACACCCGTTCTAACCAGAACA
CCTGCATCAACCAGATGCCTTGCGTGTCCCTGGGCGAACCTATTGAGCGCGGCGACGTGCTGGCAGACGGCCCGTCCACC
GACCTCGGTGAGCTGGCGCTGGGTCAGAACATGCGTGTAGCGTTCATGCCGTGGAACGGTTACAACTTCGAAGACTCCAT
CCTCGTTTCCGAGCGTGTTGTCCAGGAAGACCGTTTCACCACTATCCACATTCAGGAACTGGCGTGCGTGTCCCGTGACA
CCAAGCTGGGGCCGGAAGAGATCACCGCTGACATCCCGAACGTGGGTGAAGCTGCGCTCTCCAAACTGGATGAATCCGGT
ATCGTTTATATCGGTGCGGAAGTGACCGGCGGCGACATTCTGGTTGGTAAGGTAACGCCGAAAGGTGAAACCCAGCTGAC
GCCGGAAGAGAAACTGCTGCGCGCGATCTTCGGCGAGAAAGCGTCTGACGTTAAAGACTCTTCTCTGCGCGTACCGAACG
GTGTCTCCGGTACCGTTATCGACGTTCAGGTCTTTACCCGTGACGGCGTAGAAAAAGACAAACGTGCTCTGGAAATCGAA
GAGATGCAGCTGAAGCAGGCCAAAAAAGACCTGTCTGAAGAACTGCAGATCCTCGAAGCCGGTCTGTTCAGTCGTATCTA
CGCGGTGCTGGTCTCCGGTGGCGTTGAAGCTGAGAAGCTCGACAAGCTGCCTCGCGATCGCTGGCTGGAACTGGGCCTGA
CCGACGAAGAGAAACAAAATCAGCTGGAACAGCTGGCTGAGCAGTATGACGAACTGAAACACGAGTTCGAGAAAAAACTC
GAAGCGAAACGCCGTAAAATCACCCAAGGCGACGATCTGGCACCGGGCGTGCTGAAGATTGTTAAGGTATATCTGGCCGT
TAAACGCCGTATCCAGCCTGGTGATAAGATGGCAGGTCGTCACGGTAACAAGGGTGTTATCTCTAAGATCAACCCGATCG
AAGATATGCCGCACGATGCTAACGGTACGCCGGTAGATATCGTACTGAACCCGCTGGGCGTACCGTCTCGTATGAACATC
GGTCAGATCCTTGAAACTCACCTGGGTATGGCTGCAAAAGGCATCGGCGATAAGATCAACGCCATGCTGAAGCAGCAGCA
GGAAGTCGCGAAACTGCGCGAATTCATCCAGCGTGCTTACGATCTGGGCGCTGACGTTCGCCAGAAAGTTGACCTGAATA
CCTTCAGCGATGAAGAAGTTCTGCGTCTGGCTGAAAACCTGCGTAAAGGCATGCCGATCGCAACGCCGGTATTCGACGGT
GCGAAAGAAGCTGAAATCAAAGAGCTGCTGCAGCTGGGCGACCTGCCGACTTCCGGTCAGATCACCCTGTTTGATGGCCG
CACCGGTGAACAGTTCGAACGTCCGGTAACCGTGGGTTACATGTACATGCTGAAACTGAACCACCTGGTCGACGACAAAA
TGCACGCTCGTTCCACCGGTTCTTACAGCCTGGTTACTCAGCAGCCGCTGGGTGGTAAGGCACAGTTCGGTGGTCAGCGT
TTCGGTGAGATGGAAGTGTGGGCGCTGGAAGCATACGGCGCGGCCTACACCCTGCAGGAAATGCTCACCGTTAAGTCTGA
TGACGTGAACGGTCGTACCAAGATGTATAAAAACATCGTGGACGGCAATCACCAGATGGAACCGGGCATGCCGGAATCCT
TCAACGTACTGTTGAAAGAAATTCGCTCGCTGGGCATCAACATCGAACTGGAAGACGAGTAA

Upstream 100 bases:

>100_bases
ATGAAATGGTTTAAGCGTGATAGCAACAGGCATTGCGGAAAGTGTTCCATTTTCCGGTCAACAAAATAGTGTTGCATAAA
AAACTGCCCTCTGCGGGCAG

Downstream 100 bases:

>100_bases
TTCTCGCTCAAACAGGTCACTGCTGCCGGGTTAACGCCCGGCAGCGGAATGTGCTAACTCCGACGGGAGCAAATCCGTGA
AAGACTTATTAAAGTTTCTG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1353; Mature: 1352

Protein sequence:

>1353_residues
MGRLVSELRNPMVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQ
YVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQL
HRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVV
FEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVAAKDYIDEATGEL
ICPANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLF
FSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIEVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLV
RVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRD
VHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDENGHF
VEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVA
VDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPIERGDVLADGPST
DLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESG
IVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIE
EMQLKQAKKDLSEELQILEAGLFSRIYAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKL
EAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPHDANGTPVDIVLNPLGVPSRMNI
GQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLNTFSDEEVLRLAENLRKGMPIATPVFDG
AKEAEIKELLQLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQR
FGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE

Sequences:

>Translated_1353_residues
MGRLVSELRNPMVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQ
YVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQL
HRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVV
FEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVAAKDYIDEATGEL
ICPANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLF
FSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIEVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLV
RVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRD
VHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDENGHF
VEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVA
VDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPIERGDVLADGPST
DLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESG
IVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIE
EMQLKQAKKDLSEELQILEAGLFSRIYAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKL
EAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPHDANGTPVDIVLNPLGVPSRMNI
GQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLNTFSDEEVLRLAENLRKGMPIATPVFDG
AKEAEIKELLQLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQR
FGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
>Mature_1352_residues
GRLVSELRNPMVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQY
VSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLH
RSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVF
EIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVAAKDYIDEATGELI
CPANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFF
SEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIEVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVR
VERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDV
HPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDENGHFV
EDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAV
DSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPIERGDVLADGPSTD
LGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGI
VYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEE
MQLKQAKKDLSEELQILEAGLFSRIYAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPHDANGTPVDIVLNPLGVPSRMNIG
QILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLNTFSDEEVLRLAENLRKGMPIATPVFDGA
KEAEIKELLQLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRF
GEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI212286172, Length=257, Percent_Identity=32.6848249027237, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI33469941, Length=257, Percent_Identity=32.6848249027237, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI4505941, Length=169, Percent_Identity=31.3609467455621, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI238908505, Length=159, Percent_Identity=33.9622641509434, Blast_Score=78, Evalue=6e-14,
Organism=Homo sapiens, GI238908503, Length=159, Percent_Identity=33.9622641509434, Blast_Score=78, Evalue=6e-14,
Organism=Escherichia coli, GI1790419, Length=1342, Percent_Identity=98.2861400894188, Blast_Score=2708, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=315, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17506623, Length=234, Percent_Identity=30.7692307692308, Blast_Score=109, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17552304, Length=114, Percent_Identity=35.9649122807018, Blast_Score=74, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324725, Length=250, Percent_Identity=31.2, Blast_Score=107, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6325267, Length=250, Percent_Identity=30.4, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324781, Length=168, Percent_Identity=32.7380952380952, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17136446, Length=259, Percent_Identity=33.2046332046332, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17136444, Length=249, Percent_Identity=28.1124497991968, Blast_Score=81, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17647877, Length=160, Percent_Identity=32.5, Blast_Score=78, Evalue=5e-14,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 151772; Mature: 151641

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLVSELRNPMVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGL
CCCHHHHHCCCEEEEHHHHHHHHHHHCCCCCEECCCEEEEEEHHHHHHHHHCCCCCCHHH
EAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREA
HHHHHHHCCCCCCCCCCCEEEEEHHHCCCCCCCHHHEEECEEECCCCEEEEEEEEEECCC
PEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGK
CCCHHHHHHHHHEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCE
VLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVV
EEEEEEEEEECCCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
FEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPV
HHHHCCEEEEEECHHHHCCCCCEEEEECCCEEEEECCCEEHHHHHHHHHHCCCCEEECCH
EYIAGKVAAKDYIDEATGELICPANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISE
HHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSL
EEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LRDEIEGSGILSKDDIIEVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
RVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRR
HHHHHHHHHCCCCCHHHHCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHH
ISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLET
HCCCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECEEEEEECCCCCCCCC
PYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDENGHFVEDLVTCRSKGESSLFSRDQ
CHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHCCCC
VDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVA
CCHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCEEE
VDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMP
ECCCCHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCC
CVSLGEPIERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFT
CCCCCCCCCCCCEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCE
TIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTP
EEEHHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEECCCEEEEEEECC
KGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIE
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHH
EMQLKQAKKDLSEELQILEAGLFSRIYAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHEEECCCCCHHHHH
QLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCC
HGNKGVISKINPIEDMPHDANGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKIN
CCCCCCCCCCCCHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
AMLKQQQEVAKLREFIQRAYDLGADVRQKVDLNTFSDEEVLRLAENLRKGMPIATPVFDG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
AKEAEIKELLQLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTG
CCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHCCCC
SYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIV
CEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
DGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
GRLVSELRNPMVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGL
CCHHHHHCCCEEEEHHHHHHHHHHHCCCCCEECCCEEEEEEHHHHHHHHHCCCCCCHHH
EAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREA
HHHHHHHCCCCCCCCCCCEEEEEHHHCCCCCCCHHHEEECEEECCCCEEEEEEEEEECCC
PEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGK
CCCHHHHHHHHHEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCE
VLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVV
EEEEEEEEEECCCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
FEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPV
HHHHCCEEEEEECHHHHCCCCCEEEEECCCEEEEECCCEEHHHHHHHHHHCCCCEEECCH
EYIAGKVAAKDYIDEATGELICPANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISE
HHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSL
EEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LRDEIEGSGILSKDDIIEVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
RVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRR
HHHHHHHHHCCCCCHHHHCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHH
ISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLET
HCCCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECEEEEEECCCCCCCCC
PYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDENGHFVEDLVTCRSKGESSLFSRDQ
CHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHCCCC
VDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVA
CCHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCEEE
VDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMP
ECCCCHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCC
CVSLGEPIERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFT
CCCCCCCCCCCCEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCE
TIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTP
EEEHHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEECCCEEEEEEECC
KGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIE
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHH
EMQLKQAKKDLSEELQILEAGLFSRIYAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHEEECCCCCHHHHH
QLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCC
HGNKGVISKINPIEDMPHDANGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKIN
CCCCCCCCCCCCHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
AMLKQQQEVAKLREFIQRAYDLGADVRQKVDLNTFSDEEVLRLAENLRKGMPIATPVFDG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
AKEAEIKELLQLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTG
CCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHCCCC
SYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIV
CEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
DGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA