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The map label for this gene is trkH [H]

Identifier: 238892445

GI number: 238892445

Start: 209834

End: 211285

Strand: Direct

Name: trkH [H]

Synonym: KP1_0206

Alternate gene names: 238892445

Gene position: 209834-211285 (Clockwise)

Preceding gene: 238892444

Following gene: 238892446

Centisome position: 4.0

GC content: 56.82

Gene sequence:

>1452_bases
ATGCATTTTCGCGCCATAACCCGAATCGTTGGACTGCTGGTCATCTTGTTTTCGGGGACGATGATCGTCCCGGGATTAGT
GGCCCTGATATATCGCGATGGCGCGGGACGGGCCTTCACTCAAACCTTCTTTGTCGCTCTGGCGATCGGCTCCATGCTGT
GGTGGCCGAACCGTAAGCAAAAAGGCGAACTGAAATCTCGTGAAGGGTTTCTGATCGTGGTGCTGTTCTGGACCGTGCTG
GGGAGCGTGGGGGCCTTGCCCTTTATCTTCTCCGAACAGCCGAACCTGACGGTGACGGATGCCTTCTTCGAGTCATTTTC
CGGCCTGACGACGACCGGGGCGACCACTCTGGTGGGGCTGGACTCGCTTCCGCACGCTATCCTCTTTTATCGCCAGATGC
TGCAGTGGTTCGGCGGCATGGGGATCATTGTGCTGGCGGTAGCGATTCTGCCTATCCTCGGCGTCGGGGGGATGCAGCTC
TACCGCGCGGAAATGCCCGGCCCGCTGAAGGATAACAAGATGCGTCCGCGTATTGCCGAGACGGCGAAGACATTGTGGCT
CATCTATGTGTTACTCACGATCGCCTGCGCATTGGCGCTCTGGTTTGCCGGTATGCCGGCGTTCGATGCGATCGGGCACA
GTTTCGCCACCATCGCCATCGGCGGTTTCTCGACTCACGATGCCAGCGTCGGCTATTTCAACAGCCCGATGATCAACTCC
ATCATTGCCATCTTCCTGCTGATCTCCGGCTGTAACTACGGTCTGCATTTTTCGTTGTTGAGCGGACGCAGCCTGAAGGT
GTACTGGCGCGACCCTGAATTTAGGATGTTCATTGGCGTCCAGTTGACGCTGGTCATCGTCTGTACGCTGGTGCTATGGC
TTCATAACGTGTACGGCTCGGTGTTGACGACGCTGAACCAGGCGTTTTTCCAGGTGGTGTCGATGGCGACCACCGCGGGG
TTCACCACCGATAGCATTGCACGCTGGCCGCTGTTCCTTCCGGTGCTGTTGCTGTGCTCCGCATTTATCGGCGGCTGCGC
TGGCTCCACGGGCGGTGGATTAAAAGTGATCCGTATCCTGTTGCTGTTCAAACAGGGCAACCGTGAGCTGAAGCGGTTGG
TGCACCCGAATGCGGTGTATAGCATTAAATTAGGTAACCGCGCGCTGCCGGAACGTATTCTGGAAGCAGTATGGGGATTC
TTCTCCGCCTATGCGCTGGTCTTTATCATTAGTATGCTGGCGATTATCGCCACCGGGGTGGATGACTTCTCTGCTTTCGC
CTCCGTGGTGGCGACATTGAACAACCTCGGGCCTGGGCTCGGCGTCGTCGCGGATAACTTTGCCACCATGAACCCGGTCG
CGAAATGGATCCTGATTGCTAATATGCTGTTTGGTCGTCTGGAAGTGTTCACCTTACTGGTGCTCTTTACCCCCACTTTC
TGGCGCGAATAA

Upstream 100 bases:

>100_bases
TTTCAGCAAGACTGGCTGATTTTAGTCGTGGTTCATTGCAATTACTGAAGATTAACGAATAATCCCCTCTGTTTTTTGCC
TATCAAAGGAAGCGCCAGAG

Downstream 100 bases:

>100_bases
CAGGAGTGCTCGTGAAAACTTTAATTCTCTTCTCCACCCGCGACGGGCAGACCCGTGAAATCGCTTCGTTTCTCGCCTCT
GAGCTTAAAGAGCTGGGCAT

Product: potassium transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MHFRAITRIVGLLVILFSGTMIVPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKQKGELKSREGFLIVVLFWTVL
GSVGALPFIFSEQPNLTVTDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWFAGMPAFDAIGHSFATIAIGGFSTHDASVGYFNSPMINS
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQLTLVIVCTLVLWLHNVYGSVLTTLNQAFFQVVSMATTAG
FTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGF
FSAYALVFIISMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFATMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
WRE

Sequences:

>Translated_483_residues
MHFRAITRIVGLLVILFSGTMIVPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKQKGELKSREGFLIVVLFWTVL
GSVGALPFIFSEQPNLTVTDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWFAGMPAFDAIGHSFATIAIGGFSTHDASVGYFNSPMINS
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQLTLVIVCTLVLWLHNVYGSVLTTLNQAFFQVVSMATTAG
FTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGF
FSAYALVFIISMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFATMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
WRE
>Mature_483_residues
MHFRAITRIVGLLVILFSGTMIVPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKQKGELKSREGFLIVVLFWTVL
GSVGALPFIFSEQPNLTVTDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWFAGMPAFDAIGHSFATIAIGGFSTHDASVGYFNSPMINS
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQLTLVIVCTLVLWLHNVYGSVLTTLNQAFFQVVSMATTAG
FTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGF
FSAYALVFIISMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFATMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
WRE

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=483, Percent_Identity=95.6521739130435, Blast_Score=891, Evalue=0.0,
Organism=Escherichia coli, GI1787626, Length=485, Percent_Identity=41.6494845360825, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52868; Mature: 52868

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFRAITRIVGLLVILFSGTMIVPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKQ
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KGELKSREGFLIVVLFWTVLGSVGALPFIFSEQPNLTVTDAFFESFSGLTTTGATTLVGL
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEHHHHHHHHCCCCCCCCHHHHCC
DSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
HHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTIACALALWFAGMPAFDAIGHSFATIAIGGFSTHDASVGYFNSPMINS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHH
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQLTLVIVCTLVLWLHNVYGS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
VLTTLNQAFFQVVSMATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGFFSAYALVFIISMLAIIATGV
HHHHCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDFSAFASVVATLNNLGPGLGVVADNFATMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
HHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRE
CCC
>Mature Secondary Structure
MHFRAITRIVGLLVILFSGTMIVPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKQ
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KGELKSREGFLIVVLFWTVLGSVGALPFIFSEQPNLTVTDAFFESFSGLTTTGATTLVGL
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEHHHHHHHHCCCCCCCCHHHHCC
DSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
HHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTIACALALWFAGMPAFDAIGHSFATIAIGGFSTHDASVGYFNSPMINS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHH
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQLTLVIVCTLVLWLHNVYGS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
VLTTLNQAFFQVVSMATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGFFSAYALVFIISMLAIIATGV
HHHHCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDFSAFASVVATLNNLGPGLGVVADNFATMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
HHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]