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The map label for this gene is xerC [H]

Identifier: 238892411

GI number: 238892411

Start: 173976

End: 174878

Strand: Direct

Name: xerC [H]

Synonym: KP1_0170

Alternate gene names: 238892411

Gene position: 173976-174878 (Clockwise)

Preceding gene: 238892410

Following gene: 238892412

Centisome position: 3.31

GC content: 60.13

Gene sequence:

>903_bases
ATGACCGATTCTCCTCTCTTCTCCGCCGTCGCCCGCTTTCTTCGCCATCTTGGCGTTGAACGCCAGCTCAGCCCGATCAC
GTTACTGAATTACCAGCGACAGCTGGACGCGCTGATCGCCCTGGCGGATGAGGCGGGCCTGAAAAGCTGGTCGCAGTGCG
ATGCCGCTCAGGTGCGAAGCTTTGCGGTGCGTAGTCGCCGCGCGGGGTTAGGCCCGGCAAGCCTGGCGCTTCGCCTGTCG
GCGCTGCGCAGTTTCTTCGACTGGCTGGTCGGCCAGGGCGAGCTCAGCGCCAATCCGGCGAAGGGGATTGCCGCGCCGAA
AATTCCCCGCCACCTGCCAAAAAATATTGACGTCGATGACGTCAATCGACTGCTGGATATCGATCTCAACGATCCGCTGG
CGGTGCGCGATCGGGCGATGCTGGAGGTGATGTACGGCGCGGGATTGCGTTTGTCCGAACTGGTCAACCTGGATATCAAA
CACCTCGATCTCGAAAGCGGTGAGGTCTGGGTGATGGGCAAAGGCAGCAAAGAGCGCCGTTTACCGATCGGTCGCAACGC
GGTGGCATGGATTGAGCACTGGCTGGATTTGCGCGGCCTGTTCGGTACCGATGACGACGCGCTGTTTTTGTCGAAGCTGG
GCAAACGTATTTCGGCACGCAACGTACAGAAGCGATTCGCCGAGTGGGGCATTAAGCAGGGGCTGAACAGCCATGTACAC
CCGCACAAGCTGCGCCACTCCTTTGCCACCCATATGCTGGAGTCGAGCGGCGATCTGCGCGGCGTGCAGGAGCTGCTGGG
GCATGCTAACCTCTCCACCACCCAAATCTATACCCATCTTGATTTTCAACACCTTGCCTCGGTGTACGATGCCGCGCATC
CGCGCGCTAAACGGGGGAAATAA

Upstream 100 bases:

>100_bases
GCCGCGATGCGCAGCATTATCAGCCAGGGCAGGGGACGCAGCTGTTGCAGGAGATTGCCCAGATGCTGCCCGGCCTGCTG
GAGCGCTGGATTGAACGCGC

Downstream 100 bases:

>100_bases
TGCGTTTTTACCGACCTCTGGGCCAGATTTCCGCGCTGACGTTTGACCTGGACGATACCCTTTACGATAACCGCCCGGTG
ATTGACCGGACGATGCACGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTDSPLFSAVARFLRHLGVERQLSPITLLNYQRQLDALIALADEAGLKSWSQCDAAQVRSFAVRSRRAGLGPASLALRLS
ALRSFFDWLVGQGELSANPAKGIAAPKIPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVNLDIK
HLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRGLFGTDDDALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Sequences:

>Translated_300_residues
MTDSPLFSAVARFLRHLGVERQLSPITLLNYQRQLDALIALADEAGLKSWSQCDAAQVRSFAVRSRRAGLGPASLALRLS
ALRSFFDWLVGQGELSANPAKGIAAPKIPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVNLDIK
HLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRGLFGTDDDALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
>Mature_299_residues
TDSPLFSAVARFLRHLGVERQLSPITLLNYQRQLDALIALADEAGLKSWSQCDAAQVRSFAVRSRRAGLGPASLALRLSA
LRSFFDWLVGQGELSANPAKGIAAPKIPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVNLDIKH
LDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRGLFGTDDDALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVHP
HKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=88, Blast_Score=539, Evalue=1e-155,
Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=38.1756756756757, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=28.1767955801105, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33460; Mature: 33329

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSPLFSAVARFLRHLGVERQLSPITLLNYQRQLDALIALADEAGLKSWSQCDAAQVRS
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHH
FAVRSRRAGLGPASLALRLSALRSFFDWLVGQGELSANPAKGIAAPKIPRHLPKNIDVDD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCHHH
VNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVNLDIKHLDLESGEVWVMGKGSKERR
HHHEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHEEECCCCCEEEEECCCCCCC
LPIGRNAVAWIEHWLDLRGLFGTDDDALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDSPLFSAVARFLRHLGVERQLSPITLLNYQRQLDALIALADEAGLKSWSQCDAAQVRS
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHH
FAVRSRRAGLGPASLALRLSALRSFFDWLVGQGELSANPAKGIAAPKIPRHLPKNIDVDD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCHHH
VNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVNLDIKHLDLESGEVWVMGKGSKERR
HHHEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHEEECCCCCEEEEECCCCCCC
LPIGRNAVAWIEHWLDLRGLFGTDDDALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]