Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 238892355

GI number: 238892355

Start: 108846

End: 109850

Strand: Direct

Name: argC [H]

Synonym: KP1_0110

Alternate gene names: 238892355

Gene position: 108846-109850 (Clockwise)

Preceding gene: 238892352

Following gene: 238892356

Centisome position: 2.07

GC content: 56.22

Gene sequence:

>1005_bases
ATGTTAAATACGCTGATTGTGGGTGCCAGTGGTTATGCCGGCGCAGAGCTGGTGACCTATATCAATCGTCATCCGCATAT
GAACATAACCGCTTTGACGGTCTCCGCGCAAAGCAATGATGCGGGAAAATTAATTTCCGACCTGCATCCGCAGCTCAAAG
GCATTGTCGATATGCCGCTGCAGCCGATGTCCGATATCAGCGAATTCAGCGCTGGCGTGGACGTGGTGTTTCTCGCCACC
GCGCACGAAGTGAGTCACGATCTGGCGCCGCAGTTTCTTGCCGCTGGCTGCGTGGTGTTCGATCTCTCCGGTGCCTTCCG
CGTTAACGATGGGGCGTTCTACGAAAAATATTACGGTTTCACTCATCGGCATCCCGACCTGCTCAAACAGGCGGTGTATG
GTCTGGCGGAGTGGAGCGCGGATGCGCTTAAAGACGCGCAGTTAATCGCAGTGCCAGGCTGCTATCCGACGGCGGCGCAG
CTGTCGCTGAAGCCGCTGATTGAGGCCAATCTGCTGGATCTCAACCAGTGGCCGGTAATCAACGCTACCAGCGGGGTGAG
CGGCGCGGGTCGTAAGGTCGCGATCGGCAACAGCTTCTGTGAAGTTAGCCTGCAGCCGTACGGCATATTTAACCATCGCC
ATCAGCCGGAGATTGCCAGCCACCTCGGGGCAAAGGTAATTTTTACCCCGCACCTGGGTAATTTTAAGCGCGGCATCCTG
GAAACCATTACCTGCCGCCTGAAACCGGGCGTCGGCCATACGCAGATCGCGGCGGTTTACCAGCAGGCTTACGCCGATAA
ACCACTGGTACGTTTATATGATAAAGGCGTGCCCGCTTTGAAAAGCGTCGAAGGCCTGCCATTCTGTGATATCGGTTTTG
CCGTGCAGGACGATCATCTCATCGTCGTCGCGGCAGAGGATAACCTGCTGAAAGGCGCCGCAGCGCAGGCGGTGCAGTGC
GCGAATATTCGTTTCGGCTTCGCTGAGACGCAGTCTCTTATTTAA

Upstream 100 bases:

>100_bases
TGGGTCGTGATAGTATCAATATTCATGCATTTATTGTGAATAAAAATACAATATCGTTGAGCGTAAGAAAACCCATCGAA
TGTAAGGAGATGCGCTTCCA

Downstream 100 bases:

>100_bases
GGTGTGATGATGAACCCATTAATTATCAAACTTGGCGGCGTATTACTCGATAGCGAAGAAGCGCTGGAGCGCCTGTTTAC
CGCGCTGGTTAACTACCGTG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLNTLIVGASGYAGAELVTYINRHPHMNITALTVSAQSNDAGKLISDLHPQLKGIVDMPLQPMSDISEFSAGVDVVFLAT
AHEVSHDLAPQFLAAGCVVFDLSGAFRVNDGAFYEKYYGFTHRHPDLLKQAVYGLAEWSADALKDAQLIAVPGCYPTAAQ
LSLKPLIEANLLDLNQWPVINATSGVSGAGRKVAIGNSFCEVSLQPYGIFNHRHQPEIASHLGAKVIFTPHLGNFKRGIL
ETITCRLKPGVGHTQIAAVYQQAYADKPLVRLYDKGVPALKSVEGLPFCDIGFAVQDDHLIVVAAEDNLLKGAAAQAVQC
ANIRFGFAETQSLI

Sequences:

>Translated_334_residues
MLNTLIVGASGYAGAELVTYINRHPHMNITALTVSAQSNDAGKLISDLHPQLKGIVDMPLQPMSDISEFSAGVDVVFLAT
AHEVSHDLAPQFLAAGCVVFDLSGAFRVNDGAFYEKYYGFTHRHPDLLKQAVYGLAEWSADALKDAQLIAVPGCYPTAAQ
LSLKPLIEANLLDLNQWPVINATSGVSGAGRKVAIGNSFCEVSLQPYGIFNHRHQPEIASHLGAKVIFTPHLGNFKRGIL
ETITCRLKPGVGHTQIAAVYQQAYADKPLVRLYDKGVPALKSVEGLPFCDIGFAVQDDHLIVVAAEDNLLKGAAAQAVQC
ANIRFGFAETQSLI
>Mature_334_residues
MLNTLIVGASGYAGAELVTYINRHPHMNITALTVSAQSNDAGKLISDLHPQLKGIVDMPLQPMSDISEFSAGVDVVFLAT
AHEVSHDLAPQFLAAGCVVFDLSGAFRVNDGAFYEKYYGFTHRHPDLLKQAVYGLAEWSADALKDAQLIAVPGCYPTAAQ
LSLKPLIEANLLDLNQWPVINATSGVSGAGRKVAIGNSFCEVSLQPYGIFNHRHQPEIASHLGAKVIFTPHLGNFKRGIL
ETITCRLKPGVGHTQIAAVYQQAYADKPLVRLYDKGVPALKSVEGLPFCDIGFAVQDDHLIVVAAEDNLLKGAAAQAVQC
ANIRFGFAETQSLI

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=87.4251497005988, Blast_Score=594, Evalue=1e-171,
Organism=Saccharomyces cerevisiae, GI6320913, Length=333, Percent_Identity=30.3303303303303, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35874; Mature: 35874

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTLIVGASGYAGAELVTYINRHPHMNITALTVSAQSNDAGKLISDLHPQLKGIVDMPL
CCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHCHHHHHHHCCCC
QPMSDISEFSAGVDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVNDGAFYEKYYGF
CCHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCHHHHHCCC
THRHPDLLKQAVYGLAEWSADALKDAQLIAVPGCYPTAAQLSLKPLIEANLLDLNQWPVI
CCCCHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCHHHEEECHHHCCCEEECCCCCEE
NATSGVSGAGRKVAIGNSFCEVSLQPYGIFNHRHQPEIASHLGAKVIFTPHLGNFKRGIL
ECCCCCCCCCCEEEECCCEEEEEECCEEECCCCCCCHHHHHCCCEEEEECCCCCHHHHHH
ETITCRLKPGVGHTQIAAVYQQAYADKPLVRLYDKGVPALKSVEGLPFCDIGFAVQDDHL
HHHEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHCCCCCEEECCCEEECCCE
IVVAAEDNLLKGAAAQAVQCANIRFGFAETQSLI
EEEECCCCCHHHHHHHHEEECCEEECCHHHHCCC
>Mature Secondary Structure
MLNTLIVGASGYAGAELVTYINRHPHMNITALTVSAQSNDAGKLISDLHPQLKGIVDMPL
CCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHCHHHHHHHCCCC
QPMSDISEFSAGVDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVNDGAFYEKYYGF
CCHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCHHHHHCCC
THRHPDLLKQAVYGLAEWSADALKDAQLIAVPGCYPTAAQLSLKPLIEANLLDLNQWPVI
CCCCHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCHHHEEECHHHCCCEEECCCCCEE
NATSGVSGAGRKVAIGNSFCEVSLQPYGIFNHRHQPEIASHLGAKVIFTPHLGNFKRGIL
ECCCCCCCCCCEEEECCCEEEEEECCEEECCCCCCCHHHHHCCCEEEEECCCCCHHHHHH
ETITCRLKPGVGHTQIAAVYQQAYADKPLVRLYDKGVPALKSVEGLPFCDIGFAVQDDHL
HHHEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHCCCCCEEECCCEEECCCE
IVVAAEDNLLKGAAAQAVQCANIRFGFAETQSLI
EEEECCCCCHHHHHHHHEEECCEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]