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The map label for this gene is metJ [H]

Identifier: 238892340

GI number: 238892340

Start: 90339

End: 90818

Strand: Reverse

Name: metJ [H]

Synonym: KP1_0094

Alternate gene names: 238892340

Gene position: 90818-90339 (Counterclockwise)

Preceding gene: 238892343

Following gene: 238892338

Centisome position: 1.73

GC content: 49.79

Gene sequence:

>480_bases
TTGAGCAAAGTGCAAATAGCCGTTAAAATTATATGCATTAGCGCACGTCGTCGGCGGCTTATCTCATGTCAGAAAGCCCG
CGCATACGGTAAACTACGCGCAATTATAGCCCGGGCGGAATATTCTGGCCCTTCACTAATAAACAGAGGATTAAGGTATC
TCATGGCTGAATGGAGCGGCGAATATATCAGCCCATACGCTGAGCACGGTAAGAAGAGTGAACAAGTAAAGAAAATTACG
GTTTCCATTCCTCTGAAGGTGTTAAAAATCCTCACCGATGAACGCACGCGTCGTCAGGTGAATAACCTGCGTCACGCGAC
CAACAGCGAGCTGCTGTGCGAAGCGTTTCTGCATGCCTTTACCGGACAACCGTTGCCTAACGATGAAGACCTGCGTAAAG
AGCGCAGCGATGAGATCCCGGAAGCGGCGAAAGCGATTATGCGTGAACTGGGAATCGACCCGGATACGTGGGAATACTGA

Upstream 100 bases:

>100_bases
GAAGTTCCTGGGCTGAATCGGTGAAAAGTCAGGCTCCAGAGTAATCATTGTCACAATAGACGTCAATACATCTGGACATC
TAAACTTCTTTGCGTATAGA

Downstream 100 bases:

>100_bases
GACGATAAAAAGGGCGGAATAATCTTCCGCCCTTTTTTCTTTCCCGCCCAGGCAGGCGGAAGAGACAAAAAAGCCGCCCT
GAGGCGGCTTCTTCTGGCAA

Product: transcriptional repressor protein MetJ

Products: NA

Alternate protein names: Met regulon regulatory protein metJ [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSKVQIAVKIICISARRRRLISCQKARAYGKLRAIIARAEYSGPSLINRGLRYLMAEWSGEYISPYAEHGKKSEQVKKIT
VSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPNDEDLRKERSDEIPEAAKAIMRELGIDPDTWEY

Sequences:

>Translated_159_residues
MSKVQIAVKIICISARRRRLISCQKARAYGKLRAIIARAEYSGPSLINRGLRYLMAEWSGEYISPYAEHGKKSEQVKKIT
VSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPNDEDLRKERSDEIPEAAKAIMRELGIDPDTWEY
>Mature_158_residues
SKVQIAVKIICISARRRRLISCQKARAYGKLRAIIARAEYSGPSLINRGLRYLMAEWSGEYISPYAEHGKKSEQVKKITV
SIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPNDEDLRKERSDEIPEAAKAIMRELGIDPDTWEY

Specific function: This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis [H]

COG id: COG3060

COG function: function code KE; Transcriptional regulator of met regulon

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metJ family [H]

Homologues:

Organism=Escherichia coli, GI1790373, Length=105, Percent_Identity=94.2857142857143, Blast_Score=211, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002084
- InterPro:   IPR010985
- ProDom:   PD020365 [H]

Pfam domain/function: PF01340 MetJ [H]

EC number: NA

Molecular weight: Translated: 18224; Mature: 18093

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVQIAVKIICISARRRRLISCQKARAYGKLRAIIARAEYSGPSLINRGLRYLMAEWSG
CCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
EYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAF
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHH
TGQPLPNDEDLRKERSDEIPEAAKAIMRELGIDPDTWEY
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKVQIAVKIICISARRRRLISCQKARAYGKLRAIIARAEYSGPSLINRGLRYLMAEWSG
CCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
EYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAF
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHH
TGQPLPNDEDLRKERSDEIPEAAKAIMRELGIDPDTWEY
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA