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The map label for this gene is yjcE [H]

Identifier: 238028789

GI number: 238028789

Start: 3699656

End: 3701329

Strand: Direct

Name: yjcE [H]

Synonym: bglu_1g32530

Alternate gene names: 238028789

Gene position: 3699656-3701329 (Clockwise)

Preceding gene: 238028782

Following gene: 238028792

Centisome position: 94.7

GC content: 70.67

Gene sequence:

>1674_bases
ATGGAAATCGTCTTCACCGTCCTGATCCTGCTGCTTGCCGTGGCGCTGTCCGGCATCGTGATCCGGCTGCTGCCGTGGCG
CCCGCCGCTGCCGCTGCTGCAGATCGCGTTCGGCGCCGTGCTGGCCTGGCCGCGGCTGAACCTGCACGTCACCTTCGATC
CCGAGCTGTTCATGCTGCTGTTCATTCCGCCGCTGCTGTTCGCGGACGGCTGGCGGATTCCGAAGCGCGAGCTCTACCTC
CAGCGGCGCGCGATCCTGATGCTCGCGTTCGGGCTGGTGTTCATCACGGTGGTGGCGGTGGGCTACTTCGCGCACTGGCT
GATTCCGGAGCTGCCGCTGCCGGTGGCGTTCGCGCTGGCCGCGGTGCTCTCGCCCACCGACGCGGTGGCGCTGTCGGGCA
TCGCCGGCCGGGGCAGGATCGCGCCGCAGCTGATGCATATCCTGGAAGGCGAGGCGCTGATGAACGACGCCTCCGGCCTG
GTGGCGCTGAAGTTCGCGATCGCGGCCGCGCTCACCGGCCTGTTCTCGCTGCGCGACGCCTCGATCACCTTCGTGATCGT
CGCCTCGGGCGGGCTCGCGGTGGGCGCGCTGCTGGCCTGGCTGTTCAGCGCGCTCTCCACGCGCTTCTTGAACGCCGCGC
AGGAGGGCGACCCGGCGCCGGGCATCGTGATGACGCTGCTGATCCCGTTCGCGTCCTACCTGATCGCCGAGCACTTCGGG
CTGTCGGGCATTCTGTCGGCGGTGGCGGCCGGGATGATGATGAACTACACGAGCTTCTCGCGCAGCAGCACGGTGGCCGC
GCGGGTGCGCGCCGAGAGCACCTGGTCGATGATCGAGTTCGTGTTCAACGGCATGGTGTTCATCATGCTGGGCCTGCAGA
TGCCGCAGATCATCGGCCGCGCGCTGCTGTCGGCGCACCACGAGAGCGACGCGCGGATGCTGGCGATGATCGGCTACGTG
ATCGCGATGCTGGGCGCGCTCTACGCGATCCGCTTCACCTGGATCTGGCTGCTGCGCTCGATCGCGAGCCGCCGCGCGGC
GCGGCGCGGCATGCCCGGCGCCTTGCCGGGGTTTCGCACCATCTCGCTGATGACGGTGGGTGGCGTGCGCGGCGCGGTCA
CGCTGGCCGGCGTGCTGTCGCTGCCGGTCGCGCTCGGCAACGGCACGCCGCTGGCCGGCCGCGACACGGCGATCTTCGTC
GCCTCGGGGGTGATCCTCGGCTCGCTGCTGGTGGCCGTGGTCGGGCTGCCGCTGCTGCTGCGCGGGATGCGCACCGTCCC
GCATCCGCATGCGCACGAGGAGCGCGCGGCGCGCGCGGCGGCCGCGCAGGCCGCGATCCGCGCGATCGACGCGACCCACG
ACACGCTGACCGCCGATCTCGACGAGGCCGACGCCGCGCGCTGCGCCGACATCACCGCGCGCGTGATGGATCGATACCGG
CGCCGCCTGGTGGCGCTCGACGACGGCGAGGACGCCGCCACGCTGCGCGCGGAGGCCAAGCAGGCCGAGCGCATGGAGCT
GCAGATGAAGATCGCGGCGGTGCGCGCCGAACGCGCGGCGCTGTACCGGATGCGCACCGAACAGAAGATCAACGACGTGA
CGCTCGCCAAGCTGATGCGCGAGGTCGATCTGTCGGAGACGGCCCTGTCCACGCGCAAGAAAGGGCTCGTCTGA

Upstream 100 bases:

>100_bases
CGGGGCTCGCTCGCACCAAACCGGTGCGCGGCGGCACGCCGCGCTTCTTCCGCGCGCGCTACACTCGCCCGGTCCCCGTT
TTCAAATCCCCGGCACCTCG

Downstream 100 bases:

>100_bases
GCGCCGAGAGGCCGGGATGCGGCGGCGGCGGGCGGCGCAGCCGCGCACGCCGCCCCGCCCGCCCTCGCGCCGCTCCCGCC
CGCCTTACTTCGCGACCACC

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MEIVFTVLILLLAVALSGIVIRLLPWRPPLPLLQIAFGAVLAWPRLNLHVTFDPELFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFITVVAVGYFAHWLIPELPLPVAFALAAVLSPTDAVALSGIAGRGRIAPQLMHILEGEALMNDASGL
VALKFAIAAALTGLFSLRDASITFVIVASGGLAVGALLAWLFSALSTRFLNAAQEGDPAPGIVMTLLIPFASYLIAEHFG
LSGILSAVAAGMMMNYTSFSRSSTVAARVRAESTWSMIEFVFNGMVFIMLGLQMPQIIGRALLSAHHESDARMLAMIGYV
IAMLGALYAIRFTWIWLLRSIASRRAARRGMPGALPGFRTISLMTVGGVRGAVTLAGVLSLPVALGNGTPLAGRDTAIFV
ASGVILGSLLVAVVGLPLLLRGMRTVPHPHAHEERAARAAAAQAAIRAIDATHDTLTADLDEADAARCADITARVMDRYR
RRLVALDDGEDAATLRAEAKQAERMELQMKIAAVRAERAALYRMRTEQKINDVTLAKLMREVDLSETALSTRKKGLV

Sequences:

>Translated_557_residues
MEIVFTVLILLLAVALSGIVIRLLPWRPPLPLLQIAFGAVLAWPRLNLHVTFDPELFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFITVVAVGYFAHWLIPELPLPVAFALAAVLSPTDAVALSGIAGRGRIAPQLMHILEGEALMNDASGL
VALKFAIAAALTGLFSLRDASITFVIVASGGLAVGALLAWLFSALSTRFLNAAQEGDPAPGIVMTLLIPFASYLIAEHFG
LSGILSAVAAGMMMNYTSFSRSSTVAARVRAESTWSMIEFVFNGMVFIMLGLQMPQIIGRALLSAHHESDARMLAMIGYV
IAMLGALYAIRFTWIWLLRSIASRRAARRGMPGALPGFRTISLMTVGGVRGAVTLAGVLSLPVALGNGTPLAGRDTAIFV
ASGVILGSLLVAVVGLPLLLRGMRTVPHPHAHEERAARAAAAQAAIRAIDATHDTLTADLDEADAARCADITARVMDRYR
RRLVALDDGEDAATLRAEAKQAERMELQMKIAAVRAERAALYRMRTEQKINDVTLAKLMREVDLSETALSTRKKGLV
>Mature_557_residues
MEIVFTVLILLLAVALSGIVIRLLPWRPPLPLLQIAFGAVLAWPRLNLHVTFDPELFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFITVVAVGYFAHWLIPELPLPVAFALAAVLSPTDAVALSGIAGRGRIAPQLMHILEGEALMNDASGL
VALKFAIAAALTGLFSLRDASITFVIVASGGLAVGALLAWLFSALSTRFLNAAQEGDPAPGIVMTLLIPFASYLIAEHFG
LSGILSAVAAGMMMNYTSFSRSSTVAARVRAESTWSMIEFVFNGMVFIMLGLQMPQIIGRALLSAHHESDARMLAMIGYV
IAMLGALYAIRFTWIWLLRSIASRRAARRGMPGALPGFRTISLMTVGGVRGAVTLAGVLSLPVALGNGTPLAGRDTAIFV
ASGVILGSLLVAVVGLPLLLRGMRTVPHPHAHEERAARAAAAQAAIRAIDATHDTLTADLDEADAARCADITARVMDRYR
RRLVALDDGEDAATLRAEAKQAERMELQMKIAAVRAERAALYRMRTEQKINDVTLAKLMREVDLSETALSTRKKGLV

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI41872703, Length=529, Percent_Identity=22.6843100189036, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI27734935, Length=266, Percent_Identity=23.6842105263158, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI110227626, Length=267, Percent_Identity=23.9700374531835, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI5454070, Length=267, Percent_Identity=23.9700374531835, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI294997330, Length=267, Percent_Identity=23.5955056179775, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI15529998, Length=511, Percent_Identity=20.5479452054795, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI148727259, Length=353, Percent_Identity=24.0793201133144, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI14211919, Length=260, Percent_Identity=23.8461538461538, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1790501, Length=557, Percent_Identity=47.5763016157989, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI71980847, Length=379, Percent_Identity=25.065963060686, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71999819, Length=406, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71999817, Length=406, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71999821, Length=380, Percent_Identity=26.0526315789474, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990932, Length=379, Percent_Identity=23.7467018469657, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71990924, Length=379, Percent_Identity=23.7467018469657, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71992107, Length=251, Percent_Identity=22.3107569721116, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992101, Length=251, Percent_Identity=22.3107569721116, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25150332, Length=476, Percent_Identity=21.218487394958, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71993590, Length=313, Percent_Identity=25.2396166134185, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71993582, Length=312, Percent_Identity=24.6794871794872, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=356, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221473222, Length=269, Percent_Identity=24.1635687732342, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364513, Length=269, Percent_Identity=24.1635687732342, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221473215, Length=269, Percent_Identity=24.1635687732342, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221473212, Length=269, Percent_Identity=24.1635687732342, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281360447, Length=275, Percent_Identity=28, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221510734, Length=340, Percent_Identity=25.2941176470588, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221510738, Length=340, Percent_Identity=25.2941176470588, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 60008; Mature: 60008

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVFTVLILLLAVALSGIVIRLLPWRPPLPLLQIAFGAVLAWPRLNLHVTFDPELFMLL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFITVVAVGYFAHWLIPELPLPVAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AVLSPTDAVALSGIAGRGRIAPQLMHILEGEALMNDASGLVALKFAIAAALTGLFSLRDA
HHHCCCHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
SITFVIVASGGLAVGALLAWLFSALSTRFLNAAQEGDPAPGIVMTLLIPFASYLIAEHFG
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGILSAVAAGMMMNYTSFSRSSTVAARVRAESTWSMIEFVFNGMVFIMLGLQMPQIIGR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLSAHHESDARMLAMIGYVIAMLGALYAIRFTWIWLLRSIASRRAARRGMPGALPGFRT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
ISLMTVGGVRGAVTLAGVLSLPVALGNGTPLAGRDTAIFVASGVILGSLLVAVVGLPLLL
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGMRTVPHPHAHEERAARAAAAQAAIRAIDATHDTLTADLDEADAARCADITARVMDRYR
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
RRLVALDDGEDAATLRAEAKQAERMELQMKIAAVRAERAALYRMRTEQKINDVTLAKLMR
HHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDLSETALSTRKKGLV
HHCHHHHHHHHHHCCCC
>Mature Secondary Structure
MEIVFTVLILLLAVALSGIVIRLLPWRPPLPLLQIAFGAVLAWPRLNLHVTFDPELFMLL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFITVVAVGYFAHWLIPELPLPVAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AVLSPTDAVALSGIAGRGRIAPQLMHILEGEALMNDASGLVALKFAIAAALTGLFSLRDA
HHHCCCHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
SITFVIVASGGLAVGALLAWLFSALSTRFLNAAQEGDPAPGIVMTLLIPFASYLIAEHFG
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGILSAVAAGMMMNYTSFSRSSTVAARVRAESTWSMIEFVFNGMVFIMLGLQMPQIIGR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLSAHHESDARMLAMIGYVIAMLGALYAIRFTWIWLLRSIASRRAARRGMPGALPGFRT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
ISLMTVGGVRGAVTLAGVLSLPVALGNGTPLAGRDTAIFVASGVILGSLLVAVVGLPLLL
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGMRTVPHPHAHEERAARAAAAQAAIRAIDATHDTLTADLDEADAARCADITARVMDRYR
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
RRLVALDDGEDAATLRAEAKQAERMELQMKIAAVRAERAALYRMRTEQKINDVTLAKLMR
HHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDLSETALSTRKKGLV
HHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]