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The map label for this gene is bioD [H]

Identifier: 238028781

GI number: 238028781

Start: 3686187

End: 3686939

Strand: Direct

Name: bioD [H]

Synonym: bglu_1g32450

Alternate gene names: 238028781

Gene position: 3686187-3686939 (Clockwise)

Preceding gene: 238028780

Following gene: 238028782

Centisome position: 94.36

GC content: 74.9

Gene sequence:

>753_bases
ATGAGCGCGCCGACGCCACCCCGCGCCGGCACCGGCGCCCGCGCGCTATCGTGCTTCGTGACCGGCACCGACACCGAGAT
CGGCAAGACCTTCGTGTCCGCCGCGCTGCTGCACGGCTTCGCGCGCCACGGCCTGCGCGCCGCCGCGATGAAGCCGGTCG
CGGCCGGCGCCGAGGAACGCGACGGCGTGCTGCACAACGACGACGCCGACCAGCTGGACGCGGCCGCCGGCGTCGCGCTG
CCGCCCGCGATCCGCACCCCGTTCATGCTGAAGGCGCCGGCCGCGCCGCACATCGTGGCCGCGCAAGAAGGCGTGACGCT
CGACATCGGCACCATCGCGGCCGCGCACGCGAAGGCCTGCGAAGGCGCCGACGTGGTGGTGGTGGAAGGCGTGGGCGGCT
TTCGCGTGCCGCTCGGCGACTCGCTCGACACCGCCGACCTGGCCGTCGCGCTGAAGCTGCCGGTGGTACTGGTGGTGGGC
GTGCGGCTCGGCTGCATCAACCACGCGCTGCTCACCGCCGACGCGATCGCCGCGCGCGGCCTGAGCATCGCGGGCTGGGT
GGCCAACCGCGTCGACCCGGCCATGCTCTACCCCGACGAGAACATCGCCACGCTCACCCAATGGCTCGCGCGCGAGCACG
CCGCGCCGCTGCTTGGCGAGATCGCGCACCTGACACCGCCCGCGCCCGAACTGGCCGCGGGCTCGCTCGACATCGAACGG
CTCGTCGCGGCGCTCGCCGCCGCGCGGCCGTGA

Upstream 100 bases:

>100_bases
CCTCGCGGCTGCGCATCTCGCTGTCCGCCGCGCATTCGTTCGACGATCTGGCGCGGCTCGACGCGGCGCTCGCCGCCGCC
GGCGCCGCGGAGGCCGCCGC

Downstream 100 bases:

>100_bases
TACCCCGTTCCCCGCTTCCTATCGAGGACCCCACCATGATCCAAGCCCAGACCGTGACTCCGGACGCGACGACGGCACCC
GAAGCAGTGCCCGTCGGCAT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSAPTPPRAGTGARALSCFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAEERDGVLHNDDADQLDAAAGVAL
PPAIRTPFMLKAPAAPHIVAAQEGVTLDIGTIAAAHAKACEGADVVVVEGVGGFRVPLGDSLDTADLAVALKLPVVLVVG
VRLGCINHALLTADAIAARGLSIAGWVANRVDPAMLYPDENIATLTQWLAREHAAPLLGEIAHLTPPAPELAAGSLDIER
LVAALAAARP

Sequences:

>Translated_250_residues
MSAPTPPRAGTGARALSCFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAEERDGVLHNDDADQLDAAAGVAL
PPAIRTPFMLKAPAAPHIVAAQEGVTLDIGTIAAAHAKACEGADVVVVEGVGGFRVPLGDSLDTADLAVALKLPVVLVVG
VRLGCINHALLTADAIAARGLSIAGWVANRVDPAMLYPDENIATLTQWLAREHAAPLLGEIAHLTPPAPELAAGSLDIER
LVAALAAARP
>Mature_249_residues
SAPTPPRAGTGARALSCFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAEERDGVLHNDDADQLDAAAGVALP
PAIRTPFMLKAPAAPHIVAAQEGVTLDIGTIAAAHAKACEGADVVVVEGVGGFRVPLGDSLDTADLAVALKLPVVLVVGV
RLGCINHALLTADAIAARGLSIAGWVANRVDPAMLYPDENIATLTQWLAREHAAPLLGEIAHLTPPAPELAAGSLDIERL
VAALAAARP

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=206, Percent_Identity=46.6019417475728, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI87081944, Length=206, Percent_Identity=40.2912621359223, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324385, Length=170, Percent_Identity=35.2941176470588, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25366; Mature: 25235

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTPPRAGTGARALSCFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAEER
CCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHCCCCCC
DGVLHNDDADQLDAAAGVALPPAIRTPFMLKAPAAPHIVAAQEGVTLDIGTIAAAHAKAC
CCCCCCCCHHHHHHHCCCCCCHHHCCCEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHC
EGADVVVVEGVGGFRVPLGDSLDTADLAVALKLPVVLVVGVRLGCINHALLTADAIAARG
CCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSIAGWVANRVDPAMLYPDENIATLTQWLAREHAAPLLGEIAHLTPPAPELAAGSLDIER
CCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCHHH
LVAALAAARP
HHHHHHHCCC
>Mature Secondary Structure 
SAPTPPRAGTGARALSCFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAEER
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHCCCCCC
DGVLHNDDADQLDAAAGVALPPAIRTPFMLKAPAAPHIVAAQEGVTLDIGTIAAAHAKAC
CCCCCCCCHHHHHHHCCCCCCHHHCCCEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHC
EGADVVVVEGVGGFRVPLGDSLDTADLAVALKLPVVLVVGVRLGCINHALLTADAIAARG
CCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSIAGWVANRVDPAMLYPDENIATLTQWLAREHAAPLLGEIAHLTPPAPELAAGSLDIER
CCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCHHH
LVAALAAARP
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA