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The map label for this gene is dppA [H]

Identifier: 238028771

GI number: 238028771

Start: 3673643

End: 3675229

Strand: Direct

Name: dppA [H]

Synonym: bglu_1g32350

Alternate gene names: 238028771

Gene position: 3673643-3675229 (Clockwise)

Preceding gene: 238028770

Following gene: 238028773

Centisome position: 94.04

GC content: 66.23

Gene sequence:

>1587_bases
ATGCGTTTCACGATGCTCGCCGCCGCGCTCGTCGCCGCCGCCCCTCTCCTTGCCGCCGCGAAGCCGCTGACGGTGTGTAC
CGAAGCGAGCCCGGACGGCTTCGACGTCGTGCAGTACAACTCGCTCGTCACCACCAACGCGTCCGCCGACGTGATCTTCA
ATACGCTGGTGTCATACGACGAGGCGACGAAGAAGGTGGTGCCGGCGCTGGCCGACAAGTGGGACGTCAGCGCCGACGGC
CGCACCGTCACGTTCCATCTCCGGCCGAACGTCGCGTTCCAGAGCACCGACTACTTCAAGCCCACGCGCGCGCTCGACGC
CGACGACGTGGTGTTCAGCTTCTCGCGCATGCTCGACAGCGACAATCCGTGGCACAAGGTGGCCGGCCCGAGCGGCTTCC
CGCACGCGCAGTCGATGGGGCTCGTCAAGCTCGTCAAGTCGGTCACCAAGGTGGACCCGCTGACGGTGAGGTTCGAGCTG
AACGAGCCGAACGCGACCTTCGTGCCGATCCTGACGATGGGCTTCGCCTCGATCTATTCGGCCGAATACGCGGACCAGCT
GCTCAAGGCCGGCAAGCAGGCCGAGCTCAACGCCAGGCCGATCGGCACCGGCCCGTTCGTGCTGAAGCGCTACACCAAGG
ACGCGCTGATCCGCTACGACGCGAACCCCACCTACTGGGGCACCAAGCCGAAGGTGGACCGGCTGATCTATGCGATCACG
CCCGACGCGTCGGTGCGCGCGCAGAAGGTGAGGGCCGGCGAATGCCAGATCGCGCTGTCGCCGAAGCCGCAGGACGTGGC
CGCCGCGAAGGCCGACAAGGCCTTGAAAGTGGTGGAGACGCCGGCCTTCATGACCGCGTTCGTCGCACTCAACACCGAGC
ACAAGCCGCTCGACAATCCCAAGGTGCGCGAGGCGCTCAACCTCGCGTTCGATCGCGCGACCTACCTGAAGGTGGTGTTC
GACAACACCGCGACGCCGGCCACCAACCCGTATCCGCCCAACACCTGGAGCTATGCGAAGTCGGTGTCGCCGTATCCGTA
TGATCCGGCCAAGGCCAAGCGGCTGCTGGCCGAGGCCGGCTTCCCGAACGGCTTCTCGACCACCATCTGGGTGCGCCCCA
CGGGCAGCGTGCTGAACCCGAACCCGAAGGCCGGCGCCGAGCTGCTGCAGGCCGACTTCGCGAAGATCGGCGTGAAGGCC
GAGGTGAAGGTGATGGAATGGGGCGAGCTGATCAAGCGGGCCAAGCTCGGCCAGCACGACATGCTGTTCATGGGCTGGGC
CGGCGACAACGGCGATCCGGACAACTACCTGACGCCGCTGTTCAGCTGCAACGCCGTGAAGTCGGGCATCAACTTCTCGC
GCTTCTGCGACGCGCAGCTCGACCAGCTGATCGCCGAGGGCAAGGAAACCGCCGACCAGGCCAAGCGCAGCAAGGCCTAT
GAAGCCGCGCAGCAGATCATCCACGACCAGGCGCTGTGGATTCCGCTCGGCTACCCGACCGCGTCGGCCATCACGCGGCC
GAACGTGCACGGCTATCAGGTCAGCCCGTTCGGCCGCCAGCACTTCACCGAGGTGTCGGTGCAGTAA

Upstream 100 bases:

>100_bases
GTTCACGCCGCGCGTTTTTTGACGGTATGCTAGTCGGCCGGTGCCGTGGCGAACCCGCCGCCGCACCCCGACCACCGCCC
CTGTCCACCCGGGAGATCCC

Downstream 100 bases:

>100_bases
CGGCCGCCGGCGGTCGCCGGCCGAGCGCCGCACGCGTGCGCGGCGCTCGGCCGGCCCGCGGTTCAGCCCGCGCCCCGCTT
GGCGGGCCGGAACCGGAACA

Product: peptide ABC transporter periplasmic peptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MRFTMLAAALVAAAPLLAAAKPLTVCTEASPDGFDVVQYNSLVTTNASADVIFNTLVSYDEATKKVVPALADKWDVSADG
RTVTFHLRPNVAFQSTDYFKPTRALDADDVVFSFSRMLDSDNPWHKVAGPSGFPHAQSMGLVKLVKSVTKVDPLTVRFEL
NEPNATFVPILTMGFASIYSAEYADQLLKAGKQAELNARPIGTGPFVLKRYTKDALIRYDANPTYWGTKPKVDRLIYAIT
PDASVRAQKVRAGECQIALSPKPQDVAAAKADKALKVVETPAFMTAFVALNTEHKPLDNPKVREALNLAFDRATYLKVVF
DNTATPATNPYPPNTWSYAKSVSPYPYDPAKAKRLLAEAGFPNGFSTTIWVRPTGSVLNPNPKAGAELLQADFAKIGVKA
EVKVMEWGELIKRAKLGQHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFSRFCDAQLDQLIAEGKETADQAKRSKAY
EAAQQIIHDQALWIPLGYPTASAITRPNVHGYQVSPFGRQHFTEVSVQ

Sequences:

>Translated_528_residues
MRFTMLAAALVAAAPLLAAAKPLTVCTEASPDGFDVVQYNSLVTTNASADVIFNTLVSYDEATKKVVPALADKWDVSADG
RTVTFHLRPNVAFQSTDYFKPTRALDADDVVFSFSRMLDSDNPWHKVAGPSGFPHAQSMGLVKLVKSVTKVDPLTVRFEL
NEPNATFVPILTMGFASIYSAEYADQLLKAGKQAELNARPIGTGPFVLKRYTKDALIRYDANPTYWGTKPKVDRLIYAIT
PDASVRAQKVRAGECQIALSPKPQDVAAAKADKALKVVETPAFMTAFVALNTEHKPLDNPKVREALNLAFDRATYLKVVF
DNTATPATNPYPPNTWSYAKSVSPYPYDPAKAKRLLAEAGFPNGFSTTIWVRPTGSVLNPNPKAGAELLQADFAKIGVKA
EVKVMEWGELIKRAKLGQHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFSRFCDAQLDQLIAEGKETADQAKRSKAY
EAAQQIIHDQALWIPLGYPTASAITRPNVHGYQVSPFGRQHFTEVSVQ
>Mature_528_residues
MRFTMLAAALVAAAPLLAAAKPLTVCTEASPDGFDVVQYNSLVTTNASADVIFNTLVSYDEATKKVVPALADKWDVSADG
RTVTFHLRPNVAFQSTDYFKPTRALDADDVVFSFSRMLDSDNPWHKVAGPSGFPHAQSMGLVKLVKSVTKVDPLTVRFEL
NEPNATFVPILTMGFASIYSAEYADQLLKAGKQAELNARPIGTGPFVLKRYTKDALIRYDANPTYWGTKPKVDRLIYAIT
PDASVRAQKVRAGECQIALSPKPQDVAAAKADKALKVVETPAFMTAFVALNTEHKPLDNPKVREALNLAFDRATYLKVVF
DNTATPATNPYPPNTWSYAKSVSPYPYDPAKAKRLLAEAGFPNGFSTTIWVRPTGSVLNPNPKAGAELLQADFAKIGVKA
EVKVMEWGELIKRAKLGQHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFSRFCDAQLDQLIAEGKETADQAKRSKAY
EAAQQIIHDQALWIPLGYPTASAITRPNVHGYQVSPFGRQHFTEVSVQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=527, Percent_Identity=45.73055028463, Blast_Score=490, Evalue=1e-139,
Organism=Escherichia coli, GI1787551, Length=530, Percent_Identity=33.3962264150943, Blast_Score=315, Evalue=6e-87,
Organism=Escherichia coli, GI1787052, Length=531, Percent_Identity=31.0734463276836, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1787762, Length=538, Percent_Identity=24.907063197026, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789887, Length=503, Percent_Identity=24.2544731610338, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081878, Length=525, Percent_Identity=26.0952380952381, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787495, Length=523, Percent_Identity=23.9005736137667, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789397, Length=542, Percent_Identity=24.9077490774908, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57729; Mature: 57729

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTMLAAALVAAAPLLAAAKPLTVCTEASPDGFDVVQYNSLVTTNASADVIFNTLVSYD
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHHHHH
EATKKVVPALADKWDVSADGRTVTFHLRPNVAFQSTDYFKPTRALDADDVVFSFSRMLDS
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCC
DNPWHKVAGPSGFPHAQSMGLVKLVKSVTKVDPLTVRFELNEPNATFVPILTMGFASIYS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHH
AEYADQLLKAGKQAELNARPIGTGPFVLKRYTKDALIRYDANPTYWGTKPKVDRLIYAIT
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEC
PDASVRAQKVRAGECQIALSPKPQDVAAAKADKALKVVETPAFMTAFVALNTEHKPLDNP
CCCCHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHHEEEEEECCCCCCCCCH
KVREALNLAFDRATYLKVVFDNTATPATNPYPPNTWSYAKSVSPYPYDPAKAKRLLAEAG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCC
FPNGFSTTIWVRPTGSVLNPNPKAGAELLQADFAKIGVKAEVKVMEWGELIKRAKLGQHD
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCC
MLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFSRFCDAQLDQLIAEGKETADQAKRSKAY
EEEEEECCCCCCCCCHHCHHHCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
EAAQQIIHDQALWIPLGYPTASAITRPNVHGYQVSPFGRQHFTEVSVQ
HHHHHHHCCCEEEEEECCCCHHHCCCCCCCCEEECCCCHHHCEEECCC
>Mature Secondary Structure
MRFTMLAAALVAAAPLLAAAKPLTVCTEASPDGFDVVQYNSLVTTNASADVIFNTLVSYD
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHHHHH
EATKKVVPALADKWDVSADGRTVTFHLRPNVAFQSTDYFKPTRALDADDVVFSFSRMLDS
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCC
DNPWHKVAGPSGFPHAQSMGLVKLVKSVTKVDPLTVRFELNEPNATFVPILTMGFASIYS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHH
AEYADQLLKAGKQAELNARPIGTGPFVLKRYTKDALIRYDANPTYWGTKPKVDRLIYAIT
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEC
PDASVRAQKVRAGECQIALSPKPQDVAAAKADKALKVVETPAFMTAFVALNTEHKPLDNP
CCCCHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHHEEEEEECCCCCCCCCH
KVREALNLAFDRATYLKVVFDNTATPATNPYPPNTWSYAKSVSPYPYDPAKAKRLLAEAG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCC
FPNGFSTTIWVRPTGSVLNPNPKAGAELLQADFAKIGVKAEVKVMEWGELIKRAKLGQHD
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCC
MLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFSRFCDAQLDQLIAEGKETADQAKRSKAY
EEEEEECCCCCCCCCHHCHHHCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
EAAQQIIHDQALWIPLGYPTASAITRPNVHGYQVSPFGRQHFTEVSVQ
HHHHHHHCCCEEEEEECCCCHHHCCCCCCCCEEECCCCHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]