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The map label for this gene is manX [C]

Identifier: 238028720

GI number: 238028720

Start: 3615978

End: 3616448

Strand: Reverse

Name: manX [C]

Synonym: bglu_1g31840

Alternate gene names: 238028720

Gene position: 3616448-3615978 (Counterclockwise)

Preceding gene: 238028721

Following gene: 238028719

Centisome position: 92.57

GC content: 70.7

Gene sequence:

>471_bases
ATGGCTGGCATCCTGATCATCGCTCACGCCCCGCTCGCCACCGCCCTGCGGGACTGCATCTCCCATATCTACGGGGGGGT
TCCCGCGCGCATCGGCTGCATCGACGTGCTCGCGGACAGCGACCCGTCGCAGGTGATGGGCTTCGCGCATGCGGAGATCG
CGCGGCTGCGCGAGGAAAACGGCGTTCTCGTCCTGACCGACATGTACGGCGCGACCCCGGCGAACATCGCCGGCCAGCTC
GCCAAGCTCGACGGCGTGCGCGTGCTGGCCGGCGTGAACCTGCCGATGCTGGTGCGCTCGGTCTGCTACCGCACCACGCC
GATCGACACGCTGGTGGAAAAGGCGCTGGGCGGCTCGACCAAGGGCATCCACGAGATCGCCGCCGGCACGCCGCCGCCGC
GCGTGGGCCTCGGCTGCGGCGAGTGCGCGCCGATTCCGCCGGAGCCCAAGCCGCAGACCGAACCGCTTTGA

Upstream 100 bases:

>100_bases
GATTGGCCCCGAAACCGGCCTGCTACAATGCCCGTTCGCCCGGCAGGTTCATTTCCGGGCATCCGGTCCGGCGTTCGGGC
CACATTGTTGCAAGGTTGAC

Downstream 100 bases:

>100_bases
CCGGGCGGGCCCGCCCGGCGCATTCATACGCTTCCCTTCCCCCGGCGGCGCGCGCCGCCGGCAGCCTTCACCTGAACGGA
ACACCATGCTTCAACAAGAA

Product: PTS system fructose-specific transporter subunit IIA

Products: Protein Histidine; Sugar Phosphate.; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: IIA Component Of Sugar Transport PTS System; PTS System Fructose-Specific IIA Component; PTS System Fructose Subfamily Transporter Subunit IIA; Protein-N P-Phosphohistidine-Sugar Phosphotransferase; PTS System IIA Component; Sugar Transport PTS System IIA Component; PTS System Fructose IIA Component Family Protein; Pts System Fructose Subfamily IIa Component; PTS System Fructose IIA Component; PTS System IIAB Component; IIa Component Of Sugar Transport PTS System; Pts System IIa Component; Pentitol Phosphotransferase IIA Component; Phosphotransferase Mannose/Fructose-Specific Component IIA; PTS System IIA Component Domain Protein

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MAGILIIAHAPLATALRDCISHIYGGVPARIGCIDVLADSDPSQVMGFAHAEIARLREENGVLVLTDMYGATPANIAGQL
AKLDGVRVLAGVNLPMLVRSVCYRTTPIDTLVEKALGGSTKGIHEIAAGTPPPRVGLGCGECAPIPPEPKPQTEPL

Sequences:

>Translated_156_residues
MAGILIIAHAPLATALRDCISHIYGGVPARIGCIDVLADSDPSQVMGFAHAEIARLREENGVLVLTDMYGATPANIAGQL
AKLDGVRVLAGVNLPMLVRSVCYRTTPIDTLVEKALGGSTKGIHEIAAGTPPPRVGLGCGECAPIPPEPKPQTEPL
>Mature_155_residues
AGILIIAHAPLATALRDCISHIYGGVPARIGCIDVLADSDPSQVMGFAHAEIARLREENGVLVLTDMYGATPANIAGQLA
KLDGVRVLAGVNLPMLVRSVCYRTTPIDTLVEKALGGSTKGIHEIAAGTPPPRVGLGCGECAPIPPEPKPQTEPL

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 16165; Mature: 16034

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGILIIAHAPLATALRDCISHIYGGVPARIGCIDVLADSDPSQVMGFAHAEIARLREEN
CCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHCC
GVLVLTDMYGATPANIAGQLAKLDGVRVLAGVNLPMLVRSVCYRTTPIDTLVEKALGGST
CEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCC
KGIHEIAAGTPPPRVGLGCGECAPIPPEPKPQTEPL
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGILIIAHAPLATALRDCISHIYGGVPARIGCIDVLADSDPSQVMGFAHAEIARLREEN
CCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHCC
GVLVLTDMYGATPANIAGQLAKLDGVRVLAGVNLPMLVRSVCYRTTPIDTLVEKALGGST
CEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCC
KGIHEIAAGTPPPRVGLGCGECAPIPPEPKPQTEPL
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-Phosphohistidine; Sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: Protein N-Phosphohistidine + Sugar = Protein Histidine + Sugar Phosphate. phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA