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The map label for this gene is hisC2 [H]

Identifier: 238028671

GI number: 238028671

Start: 3562979

End: 3564049

Strand: Direct

Name: hisC2 [H]

Synonym: bglu_1g31350

Alternate gene names: 238028671

Gene position: 3562979-3564049 (Clockwise)

Preceding gene: 238028670

Following gene: 238028673

Centisome position: 91.21

GC content: 69.09

Gene sequence:

>1071_bases
GTGGTGAGCCGTTATTGGAGCAACATCGTCGAGCAGCTCGTTCCGTATGTGCCGGGCGAGCAGCCCGCGCTCGCGAATCC
CGTGAAGCTGAACACGAACGAGAACCCGTACCCGCCGTCGCCGCGCGTCGTCGAGGCGATCGCGCGGGAGCTCGGCGCGG
CGGGCGAAGCGCTGCGCCGCTATCCCGATCCGCTGGCCCGCGCGCTGCGCGAGACAGTGGCCGCCCATCACGGCCTCACG
CCGGAACAGGTGTTCGTCGGCAACGGTTCGGACGAAGTGCTGGCCCACACGTTCCAGGCGCTGCTGCAACACGAGCGGCC
GATCCGCTTTCCCGACGTCACCTATAGCTTCTATCCGACCTACGCGCGCCTGTACGGCGTGGAGTACGAGGCGGTGCCGC
TCGCCGACGATCTCTCGATTAGGGTCGAGGACTACCTCGGCGGCAACGGCGGCGTGCTGTTCCCGAATCCGAACGCGCCG
ACCGGCCGCGCGCTGCCGCTCGCCGAGGTCGAGCGGATCGTGGCCGGCAATCCGGATGCGGTGGTGGTGGTCGACGAAGC
CTACGTCGATTTCGGCGCCGAATCGGCGATCGGGCTGATCGACCGCCATCCGAACCTGCTGGTCGTGCATACGACCTCGA
AGGCGCGTTCGCTGGCCGGCATGCGCGTCGGCTTCGCGTTCGGCCAGGCGCCGCTGATCGAGGCGCTGAACCGCGTGAAG
GACAGCTTCAATTCGTATCCGCTCGACCGCCTCGCGCAGGTGGCCGCGCGCGCCGCCTACGAGGATCGCGAGTGGTTCGA
GTCGAACTGCGCGCGCGTGGTCGCGAGCCGCGCCCGGCTCAACGCAGCGCTCGAGGCGCTCGGCTTCGAGATCGTGCCGT
CGGCGGCGAATTTCGTGTTCGCGCGCCATCCGGGGCACGACGCCGGCGCGCTGGCCGCCGCGCTGAAGGCACGCGAGATC
TTCGTGCGGCACTTCAAGCAGCCGCGCATCGACCAATACCTGCGGATCACGGTGGGCACCGACGCCGAATGCGACCTGCT
GGTGGACGCACTGCGCGACCTGCTCGGCTGA

Upstream 100 bases:

>100_bases
GCACCGCAACGGCGCGTAGCGCGCCCCGCACGGGGCGCGGCGAGTTTTGCGCCGTGCGCGCCCGGCCTGCGTTAATCTGC
TCGTTTTCAGTCAGGAGCCC

Downstream 100 bases:

>100_bases
CGGAAGCGGCTTCGCGCCGGCGCAGCCTGCGGGAGCGGCGGGCAGGCGGCGCCCGAGACGGCGTTACGGTGTGCCGGCCT
CGCCGGCCGCCGCGACCAGC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MVSRYWSNIVEQLVPYVPGEQPALANPVKLNTNENPYPPSPRVVEAIARELGAAGEALRRYPDPLARALRETVAAHHGLT
PEQVFVGNGSDEVLAHTFQALLQHERPIRFPDVTYSFYPTYARLYGVEYEAVPLADDLSIRVEDYLGGNGGVLFPNPNAP
TGRALPLAEVERIVAGNPDAVVVVDEAYVDFGAESAIGLIDRHPNLLVVHTTSKARSLAGMRVGFAFGQAPLIEALNRVK
DSFNSYPLDRLAQVAARAAYEDREWFESNCARVVASRARLNAALEALGFEIVPSAANFVFARHPGHDAGALAAALKAREI
FVRHFKQPRIDQYLRITVGTDAECDLLVDALRDLLG

Sequences:

>Translated_356_residues
MVSRYWSNIVEQLVPYVPGEQPALANPVKLNTNENPYPPSPRVVEAIARELGAAGEALRRYPDPLARALRETVAAHHGLT
PEQVFVGNGSDEVLAHTFQALLQHERPIRFPDVTYSFYPTYARLYGVEYEAVPLADDLSIRVEDYLGGNGGVLFPNPNAP
TGRALPLAEVERIVAGNPDAVVVVDEAYVDFGAESAIGLIDRHPNLLVVHTTSKARSLAGMRVGFAFGQAPLIEALNRVK
DSFNSYPLDRLAQVAARAAYEDREWFESNCARVVASRARLNAALEALGFEIVPSAANFVFARHPGHDAGALAAALKAREI
FVRHFKQPRIDQYLRITVGTDAECDLLVDALRDLLG
>Mature_356_residues
MVSRYWSNIVEQLVPYVPGEQPALANPVKLNTNENPYPPSPRVVEAIARELGAAGEALRRYPDPLARALRETVAAHHGLT
PEQVFVGNGSDEVLAHTFQALLQHERPIRFPDVTYSFYPTYARLYGVEYEAVPLADDLSIRVEDYLGGNGGVLFPNPNAP
TGRALPLAEVERIVAGNPDAVVVVDEAYVDFGAESAIGLIDRHPNLLVVHTTSKARSLAGMRVGFAFGQAPLIEALNRVK
DSFNSYPLDRLAQVAARAAYEDREWFESNCARVVASRARLNAALEALGFEIVPSAANFVFARHPGHDAGALAAALKAREI
FVRHFKQPRIDQYLRITVGTDAECDLLVDALRDLLG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=359, Percent_Identity=31.4763231197772, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788722, Length=246, Percent_Identity=28.4552845528455, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322075, Length=363, Percent_Identity=27.8236914600551, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38957; Mature: 38957

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSRYWSNIVEQLVPYVPGEQPALANPVKLNTNENPYPPSPRVVEAIARELGAAGEALRR
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCHHHHHHHH
YPDPLARALRETVAAHHGLTPEQVFVGNGSDEVLAHTFQALLQHERPIRFPDVTYSFYPT
CCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHH
YARLYGVEYEAVPLADDLSIRVEDYLGGNGGVLFPNPNAPTGRALPLAEVERIVAGNPDA
HHHHHCCCEEEECCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCE
VVVVDEAYVDFGAESAIGLIDRHPNLLVVHTTSKARSLAGMRVGFAFGQAPLIEALNRVK
EEEEEHHHHCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DSFNSYPLDRLAQVAARAAYEDREWFESNCARVVASRARLNAALEALGFEIVPSAANFVF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEE
ARHPGHDAGALAAALKAREIFVRHFKQPRIDQYLRITVGTDAECDLLVDALRDLLG
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MVSRYWSNIVEQLVPYVPGEQPALANPVKLNTNENPYPPSPRVVEAIARELGAAGEALRR
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCHHHHHHHH
YPDPLARALRETVAAHHGLTPEQVFVGNGSDEVLAHTFQALLQHERPIRFPDVTYSFYPT
CCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHH
YARLYGVEYEAVPLADDLSIRVEDYLGGNGGVLFPNPNAPTGRALPLAEVERIVAGNPDA
HHHHHCCCEEEECCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCE
VVVVDEAYVDFGAESAIGLIDRHPNLLVVHTTSKARSLAGMRVGFAFGQAPLIEALNRVK
EEEEEHHHHCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DSFNSYPLDRLAQVAARAAYEDREWFESNCARVVASRARLNAALEALGFEIVPSAANFVF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEE
ARHPGHDAGALAAALKAREIFVRHFKQPRIDQYLRITVGTDAECDLLVDALRDLLG
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA