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The map label for this gene is apt [H]

Identifier: 238028650

GI number: 238028650

Start: 3542614

End: 3543180

Strand: Reverse

Name: apt [H]

Synonym: bglu_1g31140

Alternate gene names: 238028650

Gene position: 3543180-3542614 (Counterclockwise)

Preceding gene: 238028651

Following gene: 238028649

Centisome position: 90.7

GC content: 68.43

Gene sequence:

>567_bases
ATGAGCCATCAGCCGTCGGGCGTGTCGCCCGATCCCGCCGAGTTCGTCCGTCGCCATGTGCGCACGGTGCCGGACTGGCC
GCAGCCGGGCGTGCAGTTCCGCGACATCACGCCGATCCTGCAGAACGCGAAGGCGCTGCGCGTGCTGGTCGATCTGCTGG
TCGAGCGCTACGTCGACGCCAAGCTCGACTACGTGGCCGGGCTCGACGCGCGCGGCTTCATCATCGCGCCGATCGTCGCC
TATGAGCTGAGCGTCGGCTTCATCCCGATCCGCAAGGTCGGCAAGCTGCCGTACAAGACACGGTCGGAATCCTATGAGCT
CGAATACGGCAGCGCGACGGTGGAGATCCATGAGGACGCCTGCAAGCCCGGCGACCGCGTGATCATCGTCGACGACCTGA
TCGCCACCGGCGGCACCATGATGGCCGGCAAGAACCTGCTGGAGCACCTCGGCGCGAGCGTCGTGGAAGGCGCGGCGATC
ATCGACCTGCCCGACCTCGGCGGCTCGGCGCTGCTGCGCGGCGCGGGCCTGCCGCTCTACGCCGTCACCGAATTCGCGGG
CCACTGA

Upstream 100 bases:

>100_bases
CATGTCGAGCGGCGCGGCCCCCGCAGCCGGATATTGTTCGGACCCCATCAATTTCCGTCGGTCGCCACGGCCGACGCGCG
CCGTTTTTTTGGAGAAGTTC

Downstream 100 bases:

>100_bases
GCCGCTTGGCCGGTGGTGCCGGGCCGACCCCGGCGCGTGCCTGTTCCCCTCATCCTCTGCCAGCGAGCCGTTTAGCCATG
CCGAGCTTCCTGCTGTTCCT

Product: adenine/guanine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSHQPSGVSPDPAEFVRRHVRTVPDWPQPGVQFRDITPILQNAKALRVLVDLLVERYVDAKLDYVAGLDARGFIIAPIVA
YELSVGFIPIRKVGKLPYKTRSESYELEYGSATVEIHEDACKPGDRVIIVDDLIATGGTMMAGKNLLEHLGASVVEGAAI
IDLPDLGGSALLRGAGLPLYAVTEFAGH

Sequences:

>Translated_188_residues
MSHQPSGVSPDPAEFVRRHVRTVPDWPQPGVQFRDITPILQNAKALRVLVDLLVERYVDAKLDYVAGLDARGFIIAPIVA
YELSVGFIPIRKVGKLPYKTRSESYELEYGSATVEIHEDACKPGDRVIIVDDLIATGGTMMAGKNLLEHLGASVVEGAAI
IDLPDLGGSALLRGAGLPLYAVTEFAGH
>Mature_187_residues
SHQPSGVSPDPAEFVRRHVRTVPDWPQPGVQFRDITPILQNAKALRVLVDLLVERYVDAKLDYVAGLDARGFIIAPIVAY
ELSVGFIPIRKVGKLPYKTRSESYELEYGSATVEIHEDACKPGDRVIIVDDLIATGGTMMAGKNLLEHLGASVVEGAAII
DLPDLGGSALLRGAGLPLYAVTEFAGH

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4502171, Length=176, Percent_Identity=44.8863636363636, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI71773201, Length=128, Percent_Identity=49.21875, Blast_Score=128, Evalue=3e-30,
Organism=Escherichia coli, GI1786675, Length=175, Percent_Identity=48.5714285714286, Blast_Score=177, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17509087, Length=159, Percent_Identity=44.0251572327044, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323619, Length=166, Percent_Identity=39.1566265060241, Blast_Score=114, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6320649, Length=179, Percent_Identity=32.9608938547486, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136334, Length=173, Percent_Identity=39.3063583815029, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005764
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.7 [H]

Molecular weight: Translated: 20287; Mature: 20155

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQPSGVSPDPAEFVRRHVRTVPDWPQPGVQFRDITPILQNAKALRVLVDLLVERYVDA
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLDYVAGLDARGFIIAPIVAYELSVGFIPIRKVGKLPYKTRSESYELEYGSATVEIHEDA
HHHHHHCCCCCCEEEHHHHHHHHHCCCEEHHHHCCCCCCCCCCCEEEECCCEEEEEECCC
CKPGDRVIIVDDLIATGGTMMAGKNLLEHLGASVVEGAAIIDLPDLGGSALLRGAGLPLY
CCCCCEEEEEECHHHCCCCHHHHHHHHHHHCHHHHCCEEEEECCCCCCHHHHHCCCCCCE
AVTEFAGH
EHHHHCCC
>Mature Secondary Structure 
SHQPSGVSPDPAEFVRRHVRTVPDWPQPGVQFRDITPILQNAKALRVLVDLLVERYVDA
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLDYVAGLDARGFIIAPIVAYELSVGFIPIRKVGKLPYKTRSESYELEYGSATVEIHEDA
HHHHHHCCCCCCEEEHHHHHHHHHCCCEEHHHHCCCCCCCCCCCEEEECCCEEEEEECCC
CKPGDRVIIVDDLIATGGTMMAGKNLLEHLGASVVEGAAIIDLPDLGGSALLRGAGLPLY
CCCCCEEEEEECHHHCCCCHHHHHHHHHHHCHHHHCCEEEEECCCCCCHHHHHCCCCCCE
AVTEFAGH
EHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA