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The map label for this gene is aspS [H]

Identifier: 238028612

GI number: 238028612

Start: 3497186

End: 3498985

Strand: Reverse

Name: aspS [H]

Synonym: bglu_1g30760

Alternate gene names: 238028612

Gene position: 3498985-3497186 (Counterclockwise)

Preceding gene: 238028613

Following gene: 238028611

Centisome position: 89.57

GC content: 66.22

Gene sequence:

>1800_bases
ATGTCGATGCGAACTGAATACTGCGGTCTCGTGACCGAACACCTGCTGGGCCAAACCGTTTCGCTGTGCGGCTGGGTGCA
TCGCCGCCGCGACCACGGCGGTGTGATCTTCATCGACCTGCGCGATCGTGAGGGCCTCGTGCAGGTGGTGTGCGACCCGG
ACCGCGCGGAGATGTTCGCGGCGGCCGAGGGCGTGCGCAACGAGTTCTGCATCCAGGTGAAGGGCCTCGTGCGCGGCCGT
CCGGACGGCACGATCAACGCCGGCCTGAAGAGCGGCAAGATCGAGGTGCTGTGCCACGAGCTGACGGTGCTGAACCCGTC
GGTCACGCCGCCGTTCCAGCTCGACGACGACAATCTCTCCGAAACCACGCGCCTCACGCATCGCGTGCTCGACCTGCGCC
GTCCGCAGATGCAGCACAACCTGCGCCTGCGCTACCGGGTGGCGATCGAGGTCCGCAAGTACCTCGACGAGCAGGGCTTC
ATCGACATCGAAACGCCGATGCTGACCAAGAGCACGCCGGAAGGCGCGCGCGACTACCTGGTGCCGTCGCGCGTCAACGC
GGGCCAGTTCTTCGCGCTGCCGCAGTCGCCGCAGCTGTTCAAGCAGCTGCTGATGGTGGCGAACTTCGACCGCTACTACC
AGATCACCAAGTGCTTCCGCGACGAGGACCTGCGCGCCGACCGCCAGCCCGAATTCACGCAGATCGACTGCGAGACCTCG
TTCCTGGGCGAGCAGGAGATCCGCGACCTGTTCGAGGAAATGATCCGCCACGTCTTCCACAAGACGATCGGCGTCGAGCT
GGGCGCGAAGTTCCCGGTCATGCCGTACTCGGAAGCCATGGCGCGCTTCGGCTCGGACAAGCCGGACCTGCGCGTGAAGC
TCGAGTTCACCGAGCTGACCGACGCGATGAAGGATGTCGACTTCAAGGTGTTCAGCGCGCCGGCCAACACCAAGGACGGC
CGGGTCGCGGCGCTGCGCGTGCCCAAGGGCGGCGAGCTCACGCGCGGCGACATCGACGGCTACACCGAGTTCGTGCGCAT
CTACGGTGCCAAGGGCCTGGCATGGATCAAGGTCAACGAGAAAGCCAAGGGCCGTGACGGCCTGCAGAGCCCGATCGTGA
AGAACCTGCACGACGCGTCGATCGCCGCGATCCTCGAGCGCACCGGCGCGCAGGACGGCGACATCATCTTCTTCGCGGCC
GACCGCGCGAAGGTGGTCAACGACAGCCTCGGCGCGCTGCGCCTGAAGATCGGCCATTCGGAGTTCGGCAAGGCCAACGG
CCTCGTCGAGTCGGGCTGGAAGCCGCTGTGGGTGATCGACTTCCCGATGTTCGAGTACGACGACGAGGATGCGCGCTACG
TGGCCGCGCACCATCCGTTCACGAGCCCGAAGGACGAGCACCTCGAGTACCTCGAAACGGACCCGGGCCGCTGCCTGGCG
AAGGCCTACGACATGGTGCTGAACGGCTGGGAAATCGGCGGCGGTTCGGTGCGGATCTTCCAGGAGGACGTGCAGAGCAA
GGTGTTCCGCGCGCTGAAGATCGGGCCGGAGGAAGCCCAGGCGAAGTTCGGCTTCCTGCTCGACGCGCTGCAGTACGGCG
CGCCGCCGCACGGCGGGATCGCGTTCGGCCTCGACCGGATCATCACCATGATGGCCGGCGCCGATTCGATCCGCGACGTG
ATCGCGTTCCCGAAGACGCAGCGTGCGCAGGATCTGCTCACGCAGGCGCCGAGCCCGGTGGACGAGCGCCAGCTGAAGGA
ACTGCACATTCGCCTGCGTCAGCCGGAACAGAAGGCGTAA

Upstream 100 bases:

>100_bases
CCCGTGCCCGCACCTGCGCGTCCGCCCGTCGAGCCGCCGCTGTAATGCCCCGGGTGTGCGTGTTGCGCCCCGTTGATCAA
ACCGAACGAAAGCAAACATC

Downstream 100 bases:

>100_bases
CGCGGCGCTCGCCCGCGCCTCGCGCGGGCGGCCGTCGACGCGACGGAGCCCGGCCGGTGGCTGCACCGGCCGGGCTTTTT
ATCGTCCAGCGCCGGCGCCG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MSMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFAAAEGVRNEFCIQVKGLVRGR
PDGTINAGLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEVRKYLDEQGF
IDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLGEQEIRDLFEEMIRHVFHKTIGVELGAKFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSAPANTKDG
RVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNEKAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAA
DRAKVVNDSLGALRLKIGHSEFGKANGLVESGWKPLWVIDFPMFEYDDEDARYVAAHHPFTSPKDEHLEYLETDPGRCLA
KAYDMVLNGWEIGGGSVRIFQEDVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIITMMAGADSIRDV
IAFPKTQRAQDLLTQAPSPVDERQLKELHIRLRQPEQKA

Sequences:

>Translated_599_residues
MSMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFAAAEGVRNEFCIQVKGLVRGR
PDGTINAGLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEVRKYLDEQGF
IDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLGEQEIRDLFEEMIRHVFHKTIGVELGAKFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSAPANTKDG
RVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNEKAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAA
DRAKVVNDSLGALRLKIGHSEFGKANGLVESGWKPLWVIDFPMFEYDDEDARYVAAHHPFTSPKDEHLEYLETDPGRCLA
KAYDMVLNGWEIGGGSVRIFQEDVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIITMMAGADSIRDV
IAFPKTQRAQDLLTQAPSPVDERQLKELHIRLRQPEQKA
>Mature_598_residues
SMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFAAAEGVRNEFCIQVKGLVRGRP
DGTINAGLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEVRKYLDEQGFI
DIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSF
LGEQEIRDLFEEMIRHVFHKTIGVELGAKFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSAPANTKDGR
VAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNEKAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAAD
RAKVVNDSLGALRLKIGHSEFGKANGLVESGWKPLWVIDFPMFEYDDEDARYVAAHHPFTSPKDEHLEYLETDPGRCLAK
AYDMVLNGWEIGGGSVRIFQEDVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIITMMAGADSIRDVI
AFPKTQRAQDLLTQAPSPVDERQLKELHIRLRQPEQKA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=607, Percent_Identity=38.0560131795717, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI45439306, Length=239, Percent_Identity=29.2887029288703, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI194272210, Length=254, Percent_Identity=24.8031496062992, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI5031815, Length=254, Percent_Identity=24.8031496062992, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1788173, Length=591, Percent_Identity=58.5448392554992, Blast_Score=699, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=296, Percent_Identity=24.3243243243243, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790571, Length=291, Percent_Identity=24.7422680412371, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32566633, Length=617, Percent_Identity=34.1977309562399, Blast_Score=324, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17535927, Length=298, Percent_Identity=22.8187919463087, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994340, Length=298, Percent_Identity=22.8187919463087, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=298, Percent_Identity=22.8187919463087, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17551876, Length=284, Percent_Identity=25, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71984122, Length=291, Percent_Identity=26.8041237113402, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6325153, Length=642, Percent_Identity=33.4890965732087, Blast_Score=272, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6323011, Length=259, Percent_Identity=28.957528957529, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321807, Length=249, Percent_Identity=26.1044176706827, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320242, Length=265, Percent_Identity=24.9056603773585, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324256, Length=172, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584738, Length=606, Percent_Identity=36.3036303630363, Blast_Score=353, Evalue=3e-97,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640851, Length=249, Percent_Identity=27.710843373494, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640849, Length=249, Percent_Identity=27.710843373494, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67512; Mature: 67381

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHH
AAEGVRNEFCIQVKGLVRGRPDGTINAGLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLS
HHHCCCCCEEEEEEHHHCCCCCCCEECCCCCCCEEEEEEEEEEECCCCCCCEEECCCCCH
ETTRLTHRVLDLRRPQMQHNLRLRYRVAIEVRKYLDEQGFIDIETPMLTKSTPEGARDYL
HHHHHHHHHHHHCCCHHHCCCEEEEEEHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHCC
VPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLGEQEIRDLFEEMIRHVFHKTIGVELGAKFPVMPYSEAMARFGSDKPDLRVKLEFTELT
HCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHH
DAMKDVDFKVFSAPANTKDGRVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNE
HHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
KAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAADRAKVVNDSLGALRLKIGHS
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCEEEEEECCC
EFGKANGLVESGWKPLWVIDFPMFEYDDEDARYVAAHHPFTSPKDEHLEYLETDPGRCLA
CCCCCCCCHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCHHHHH
KAYDMVLNGWEIGGGSVRIFQEDVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGI
HHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
AFGLDRIITMMAGADSIRDVIAFPKTQRAQDLLTQAPSPVDERQLKELHIRLRQPEQKA
HHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHH
AAEGVRNEFCIQVKGLVRGRPDGTINAGLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLS
HHHCCCCCEEEEEEHHHCCCCCCCEECCCCCCCEEEEEEEEEEECCCCCCCEEECCCCCH
ETTRLTHRVLDLRRPQMQHNLRLRYRVAIEVRKYLDEQGFIDIETPMLTKSTPEGARDYL
HHHHHHHHHHHHCCCHHHCCCEEEEEEHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHCC
VPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLGEQEIRDLFEEMIRHVFHKTIGVELGAKFPVMPYSEAMARFGSDKPDLRVKLEFTELT
HCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHH
DAMKDVDFKVFSAPANTKDGRVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNE
HHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
KAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAADRAKVVNDSLGALRLKIGHS
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCEEEEEECCC
EFGKANGLVESGWKPLWVIDFPMFEYDDEDARYVAAHHPFTSPKDEHLEYLETDPGRCLA
CCCCCCCCHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCHHHHH
KAYDMVLNGWEIGGGSVRIFQEDVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGI
HHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
AFGLDRIITMMAGADSIRDVIAFPKTQRAQDLLTQAPSPVDERQLKELHIRLRQPEQKA
HHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA