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The map label for this gene is lptD [H]

Identifier: 238028598

GI number: 238028598

Start: 3479010

End: 3481367

Strand: Reverse

Name: lptD [H]

Synonym: bglu_1g30620

Alternate gene names: 238028598

Gene position: 3481367-3479010 (Counterclockwise)

Preceding gene: 238028601

Following gene: 238028597

Centisome position: 89.12

GC content: 67.18

Gene sequence:

>2358_bases
ATGCCGCCCAAACCGATTTTCCCGCTCGTATCCTGCAGCGAACCCGCGATCCGCAAACGGCGCCTCGCGGCGGCGCTGCT
CGCCGTGCCCGGTTTCGTGCCCGCGATCGCGCAGGCGCAACTGGTGGGCGCGGCCGCGCAGCCGCAGCCGCTCGGCTCTC
CCTGGGACCTGCGCCTTGCGCCGCAGCTCGAGGAACATCCGCTGCGCCCCGGCACGAAGCCGGCCGGCTTCGTGCTCGCC
GACCACGCGAGCGGCACGGTCGACCAGGACCTGGCCGCCAAGGGGTCGGCCGAGCTGCGCCGCGGCACCACGATCGTGAA
GGCCGACGCGCTGCACTACGATCAGGACACCGACATGGCCGACGCCTACGGCCACGTCACGTTGTCGGGCAGCGGCACCA
CGTTCTCGGGGCCGGAGGCCCATCTGAAGGTCGAGGCCAACCAGGGCACGATGACCACGCCGAAGTACCGCTTCACGACC
ACCGGCGGCTCGGGCAGCGCGAAGCAGGTCGAACTGCTCGACAGCGAGCGCTCGGTATTTACCGACGCGACCTACACGGC
CTGCCAGTGCGAGCAGCCGGCCTGGTACATCCGGGGCGGCCGCTTCGAGTTCGACACCGGCGCCGACGAGGGCGTGGCGC
GCGACGGCGTGCTGTTCTTCCAGGGCGTGCCGATTTTCGCGAGCCCCTGGCTGACGTTCCCGCTGTCGGGCGAGCGCCGC
AGCGGCTTCCTGCCGCCGACGGTCTCGCTGAGCTCGACCAACGGCTTCGAGCTGTCGCTGCCGTACTACTTCAACATCGC
GCCGAACCGCGACCTGACGCTGACGCCGGAGATCATCGCCAAGCGCGGCATGTTCACGCGTGCCGAGTTCCGCTATCTGT
CGCCGAACTACTCGGGCTCGCTCACGGGCGAGTTCCTGCCTAACGATCGGCTGACGCACACGAACCGCTACGCCGTCTAC
TGGGAGCACCAGCAGAACTTCGGCGGCGGCTTCGGCGGTTACGTCTATTACAACAAGGTCTCGGACAATACTTATCCGGA
AGACCTCGGCGCGACCAATCAGTTCATCAACGGCACCCAGACGCTGTACCAGCAGGAAGCGGGCCTCACCTACAACAAGG
GTCCGTGGTCGGTGCTCACGCGCTACCAGCACTGGCAGACGCTGCCGCCGTCGATCGCGCCGTATGGCCGCGAGCCGCAG
CTGAACGTGAAGTACGCGAAGTACGACGTGGGCGGCTTCGACTTCGGCGCCGAGGCCGACTACTCGCGCTTCCGGATCAC
CACGGCGGACCAGCCCGAGGGCGACCGCGTGATGTTCAACCCCTACGTCTCGTATGGGGTCTACGGTCCGGGCTACTTCA
TCGTGCCGAAGGCGCAACTGCACGTCGCGTCGTACGACCTCACGACGACGACGGGCGGCATCCCCGGCCAGCCGAAGCGT
TTCACCTACTCGATCCCGACCTTCTCGCTCGACAGCGGTCTGGAGTTCGACCGCTCGGTGCGGCTGTTCGGGCAGGACTT
CATCCAGACGCTCGAGCCGCGGCTGTTCTACGTCTACACGCCGTACCGCAACCAGCTCGACGCGCCGCTGTTCGATACCG
CCGAGTCCGACTTCGGGCTCGCCGAGATCTTCACCACCAACACCTTCGTCGGCAACGACCGGATCGCCGACGAGAACCGC
ATCACCGCCGCGCTGACCACGCGATTCCTGAACCCGGCCACGGGCGACGAGCGCGCGCGCTTCGTGATCGCGCAGCAGTA
TTACTTCACCAACCAGCGCACCACGCTGCTGCCGACCGACTCGGTCGCGCAGGCGCGCCACTCGGACCTGATCCTCGGCG
CCTCGGTGAAGCTCGGTGCCGGCTTCGCGTCGGAGACGGCGTTCCAGTACAACGCCGACAACAATCAGCTCGTGAAGTCG
AGCGTCGGCTTCGGCTACAGTCCCGGCGAGCGCAGCGTGATCAACGTGGCCTATCGCTACACGCGCGCCAATACCACGCT
CAACGGCGATCCGATCAATCAGGTGCTGATCTCGGGCCAGTGGCCGCTCACGCGCCATTTGTACGCGGTCGGCCGCTTCA
ATTACGATCTGGCCAGCAACCGGGTGGTCGACGGTCTACTCGGCTTCCAGTACGATGCCGACTGCTGGGCGCTCGGCGTC
GGCGTGCAGCGCTACGCGAACGGCGTCAACACGTCGGGCCAGCAGAGCTCGGCGACGCGCTTCATGGCGCAGCTGACGCT
CAAGGGGCTGACGAGCATCGACAACGGGCTCGTCGCCGCGTTCCGCCAGGGCATTCCGGGCTATACGCCGCTGCCGCCCC
AGGCCCCGCCGCTGGCCCGTTTCAGCAACTATGAGTAA

Upstream 100 bases:

>100_bases
CGCCTTGCTTCGTGTGCGCCGCGTCGCAGTCACGGTTCGATTGCGCGGGCCTCGACGAGCGAACGCCAGGGATCTGCCGG
GACCGATTCGCCCGATATCG

Downstream 100 bases:

>100_bases
CCAAGCTTCGCGCACCATCGCCGCGCCTGACACGGTGCCGGCCAGCCTGCTTTCAATGGAGTCTCCGTGGCAATGAAGAA
AACCCTTCGCTTCGCAGCAA

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 785; Mature: 784

Protein sequence:

>785_residues
MPPKPIFPLVSCSEPAIRKRRLAAALLAVPGFVPAIAQAQLVGAAAQPQPLGSPWDLRLAPQLEEHPLRPGTKPAGFVLA
DHASGTVDQDLAAKGSAELRRGTTIVKADALHYDQDTDMADAYGHVTLSGSGTTFSGPEAHLKVEANQGTMTTPKYRFTT
TGGSGSAKQVELLDSERSVFTDATYTACQCEQPAWYIRGGRFEFDTGADEGVARDGVLFFQGVPIFASPWLTFPLSGERR
SGFLPPTVSLSSTNGFELSLPYYFNIAPNRDLTLTPEIIAKRGMFTRAEFRYLSPNYSGSLTGEFLPNDRLTHTNRYAVY
WEHQQNFGGGFGGYVYYNKVSDNTYPEDLGATNQFINGTQTLYQQEAGLTYNKGPWSVLTRYQHWQTLPPSIAPYGREPQ
LNVKYAKYDVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGVYGPGYFIVPKAQLHVASYDLTTTTGGIPGQPKR
FTYSIPTFSLDSGLEFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQLDAPLFDTAESDFGLAEIFTTNTFVGNDRIADENR
ITAALTTRFLNPATGDERARFVIAQQYYFTNQRTTLLPTDSVAQARHSDLILGASVKLGAGFASETAFQYNADNNQLVKS
SVGFGYSPGERSVINVAYRYTRANTTLNGDPINQVLISGQWPLTRHLYAVGRFNYDLASNRVVDGLLGFQYDADCWALGV
GVQRYANGVNTSGQQSSATRFMAQLTLKGLTSIDNGLVAAFRQGIPGYTPLPPQAPPLARFSNYE

Sequences:

>Translated_785_residues
MPPKPIFPLVSCSEPAIRKRRLAAALLAVPGFVPAIAQAQLVGAAAQPQPLGSPWDLRLAPQLEEHPLRPGTKPAGFVLA
DHASGTVDQDLAAKGSAELRRGTTIVKADALHYDQDTDMADAYGHVTLSGSGTTFSGPEAHLKVEANQGTMTTPKYRFTT
TGGSGSAKQVELLDSERSVFTDATYTACQCEQPAWYIRGGRFEFDTGADEGVARDGVLFFQGVPIFASPWLTFPLSGERR
SGFLPPTVSLSSTNGFELSLPYYFNIAPNRDLTLTPEIIAKRGMFTRAEFRYLSPNYSGSLTGEFLPNDRLTHTNRYAVY
WEHQQNFGGGFGGYVYYNKVSDNTYPEDLGATNQFINGTQTLYQQEAGLTYNKGPWSVLTRYQHWQTLPPSIAPYGREPQ
LNVKYAKYDVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGVYGPGYFIVPKAQLHVASYDLTTTTGGIPGQPKR
FTYSIPTFSLDSGLEFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQLDAPLFDTAESDFGLAEIFTTNTFVGNDRIADENR
ITAALTTRFLNPATGDERARFVIAQQYYFTNQRTTLLPTDSVAQARHSDLILGASVKLGAGFASETAFQYNADNNQLVKS
SVGFGYSPGERSVINVAYRYTRANTTLNGDPINQVLISGQWPLTRHLYAVGRFNYDLASNRVVDGLLGFQYDADCWALGV
GVQRYANGVNTSGQQSSATRFMAQLTLKGLTSIDNGLVAAFRQGIPGYTPLPPQAPPLARFSNYE
>Mature_784_residues
PPKPIFPLVSCSEPAIRKRRLAAALLAVPGFVPAIAQAQLVGAAAQPQPLGSPWDLRLAPQLEEHPLRPGTKPAGFVLAD
HASGTVDQDLAAKGSAELRRGTTIVKADALHYDQDTDMADAYGHVTLSGSGTTFSGPEAHLKVEANQGTMTTPKYRFTTT
GGSGSAKQVELLDSERSVFTDATYTACQCEQPAWYIRGGRFEFDTGADEGVARDGVLFFQGVPIFASPWLTFPLSGERRS
GFLPPTVSLSSTNGFELSLPYYFNIAPNRDLTLTPEIIAKRGMFTRAEFRYLSPNYSGSLTGEFLPNDRLTHTNRYAVYW
EHQQNFGGGFGGYVYYNKVSDNTYPEDLGATNQFINGTQTLYQQEAGLTYNKGPWSVLTRYQHWQTLPPSIAPYGREPQL
NVKYAKYDVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGVYGPGYFIVPKAQLHVASYDLTTTTGGIPGQPKRF
TYSIPTFSLDSGLEFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQLDAPLFDTAESDFGLAEIFTTNTFVGNDRIADENRI
TAALTTRFLNPATGDERARFVIAQQYYFTNQRTTLLPTDSVAQARHSDLILGASVKLGAGFASETAFQYNADNNQLVKSS
VGFGYSPGERSVINVAYRYTRANTTLNGDPINQVLISGQWPLTRHLYAVGRFNYDLASNRVVDGLLGFQYDADCWALGVG
VQRYANGVNTSGQQSSATRFMAQLTLKGLTSIDNGLVAAFRQGIPGYTPLPPQAPPLARFSNYE

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=782, Percent_Identity=27.1099744245524, Blast_Score=261, Evalue=1e-70,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR007543 [H]

Pfam domain/function: PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 86401; Mature: 86270

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKPIFPLVSCSEPAIRKRRLAAALLAVPGFVPAIAQAQLVGAAAQPQPLGSPWDLRLA
CCCCCCCCEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
PQLEEHPLRPGTKPAGFVLADHASGTVDQDLAAKGSAELRRGTTIVKADALHYDQDTDMA
CCHHHCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCHHHCCCEEEEECCEECCCCCCCH
DAYGHVTLSGSGTTFSGPEAHLKVEANQGTMTTPKYRFTTTGGSGSAKQVELLDSERSVF
HCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCEE
TDATYTACQCEQPAWYIRGGRFEFDTGADEGVARDGVLFFQGVPIFASPWLTFPLSGERR
CCCCEEEEECCCCEEEEECCEEEECCCCCCCCCCCCEEEEECCCEEECCCEEEECCCCCC
SGFLPPTVSLSSTNGFELSLPYYFNIAPNRDLTLTPEIIAKRGMFTRAEFRYLSPNYSGS
CCCCCCEEEECCCCCEEEECCEEEEECCCCCEEECHHHHHHCCCCEEEEEEEECCCCCCC
LTGEFLPNDRLTHTNRYAVYWEHQQNFGGGFGGYVYYNKVSDNTYPEDLGATNQFINGTQ
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHCCCCHHHCCCHH
TLYQQEAGLTYNKGPWSVLTRYQHWQTLPPSIAPYGREPQLNVKYAKYDVGGFDFGAEAD
HHHHHHCCCEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
YSRFRITTADQPEGDRVMFNPYVSYGVYGPGYFIVPKAQLHVASYDLTTTTGGIPGQPKR
CCEEEEEECCCCCCCEEEECCCEECCCCCCCEEEEECCEEEEEEEEEEECCCCCCCCCCE
FTYSIPTFSLDSGLEFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQLDAPLFDTAESDFGL
EEEECCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCE
AEIFTTNTFVGNDRIADENRITAALTTRFLNPATGDERARFVIAQQYYFTNQRTTLLPTD
EEEEEECEEECCCCCCCCCCEEEEEHHHHCCCCCCCCCEEEEEEEEEEEECCCEEEECCH
SVAQARHSDLILGASVKLGAGFASETAFQYNADNNQLVKSSVGFGYSPGERSVINVAYRY
HHHHHCCCCEEEECCEEECCCCCCCCEEEECCCCCEEEHHCCCCCCCCCCCCEEEEEEEE
TRANTTLNGDPINQVLISGQWPLTRHLYAVGRFNYDLASNRVVDGLLGFQYDADCWALGV
EECCCCCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCHHHHHHHCCEECCCCEEECC
GVQRYANGVNTSGQQSSATRFMAQLTLKGLTSIDNGLVAAFRQGIPGYTPLPPQAPPLAR
CHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
FSNYE
CCCCC
>Mature Secondary Structure 
PPKPIFPLVSCSEPAIRKRRLAAALLAVPGFVPAIAQAQLVGAAAQPQPLGSPWDLRLA
CCCCCCCEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
PQLEEHPLRPGTKPAGFVLADHASGTVDQDLAAKGSAELRRGTTIVKADALHYDQDTDMA
CCHHHCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCHHHCCCEEEEECCEECCCCCCCH
DAYGHVTLSGSGTTFSGPEAHLKVEANQGTMTTPKYRFTTTGGSGSAKQVELLDSERSVF
HCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCEE
TDATYTACQCEQPAWYIRGGRFEFDTGADEGVARDGVLFFQGVPIFASPWLTFPLSGERR
CCCCEEEEECCCCEEEEECCEEEECCCCCCCCCCCCEEEEECCCEEECCCEEEECCCCCC
SGFLPPTVSLSSTNGFELSLPYYFNIAPNRDLTLTPEIIAKRGMFTRAEFRYLSPNYSGS
CCCCCCEEEECCCCCEEEECCEEEEECCCCCEEECHHHHHHCCCCEEEEEEEECCCCCCC
LTGEFLPNDRLTHTNRYAVYWEHQQNFGGGFGGYVYYNKVSDNTYPEDLGATNQFINGTQ
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHCCCCHHHCCCHH
TLYQQEAGLTYNKGPWSVLTRYQHWQTLPPSIAPYGREPQLNVKYAKYDVGGFDFGAEAD
HHHHHHCCCEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
YSRFRITTADQPEGDRVMFNPYVSYGVYGPGYFIVPKAQLHVASYDLTTTTGGIPGQPKR
CCEEEEEECCCCCCCEEEECCCEECCCCCCCEEEEECCEEEEEEEEEEECCCCCCCCCCE
FTYSIPTFSLDSGLEFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQLDAPLFDTAESDFGL
EEEECCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCE
AEIFTTNTFVGNDRIADENRITAALTTRFLNPATGDERARFVIAQQYYFTNQRTTLLPTD
EEEEEECEEECCCCCCCCCCEEEEEHHHHCCCCCCCCCEEEEEEEEEEEECCCEEEECCH
SVAQARHSDLILGASVKLGAGFASETAFQYNADNNQLVKSSVGFGYSPGERSVINVAYRY
HHHHHCCCCEEEECCEEECCCCCCCCEEEECCCCCEEEHHCCCCCCCCCCCCEEEEEEEE
TRANTTLNGDPINQVLISGQWPLTRHLYAVGRFNYDLASNRVVDGLLGFQYDADCWALGV
EECCCCCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCHHHHHHHCCEECCCCEEECC
GVQRYANGVNTSGQQSSATRFMAQLTLKGLTSIDNGLVAAFRQGIPGYTPLPPQAPPLAR
CHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
FSNYE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA