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The map label for this gene is glpK [H]

Identifier: 238028578

GI number: 238028578

Start: 3456345

End: 3457847

Strand: Direct

Name: glpK [H]

Synonym: bglu_1g30420

Alternate gene names: 238028578

Gene position: 3456345-3457847 (Clockwise)

Preceding gene: 238028577

Following gene: 238028579

Centisome position: 88.48

GC content: 68.8

Gene sequence:

>1503_bases
ATGCAGGATCAATACATCCTCGCACTCGACCAGGGCACGACGAGCTCACGCGCGATGCTGTTCGATCGCCAGGGCAACAT
CGTATCGATCGCCCAGAAGGAGTTCGAACAAATCTATCCGCGCCCGGGCTGGGTCGAGCACGACCCGCACGAGATCTGGT
CGACGCAGGCCGGCGTCGCCGCCGAGGCGGTCACGCGAGTCGGCCTCAACGGCACCGCGATCGCCGCGATCGGGATCACC
AACCAGCGCGAGACGACCATCGTCTGGGACCGCGAGACGGGCCAGCCGATCTACAACGCGATCGTATGGCAGGACCGCCG
CACCGCCGACTTCTGCGACGCGCTGAAGGCCGACGGCCTGGAAGCTATGGTGCGCGCGAAGACCGGCCTGCCGATCGACT
CCTACTTCTCGGGCACCAAGATCCGCTGGATCCTCGACAACGTCGAGGGCGCGCGCGAGAAGGCGCGCCAGGGCCGGCTC
GCGTTCGGCACCGTCGACAGCTGGCTGGTGTGGAACTTCACCAAGCACGAGCTGCACGTGACCGACGTGACCAACGCGTC
GCGCACCATGCTGTTCAACATCCACACGCGCCAATGGGACGACGAGCTGCTGGCCGCGCTCGACATCCCGCGCAGCATGC
TGCCCGAGGTGCGCGCCTCGTCCGAGGTCTACGGCCACACCAAGACCACCGTGTTCGCCTCGAAACTGCCGCTGGCCGGC
ATCGCGGGCGACCAGCAGGCGGCCCTGTTCGGCCAGATGTGCACCACCAAGGGCATGGTGAAGAACACCTACGGCACCGG
CTGCTTCCTCGTGATGAACACCGGCGACACGCCGATCGAGTCGAGCAACAACCTCGTCACGACCATCGCCTGGCAGGTGG
GCGACCAGGTGAACTACGCGCTCGAAGGCAGCATCTTCATCGCCGGCGCGGTGGTGCAGTGGCTGCGCGACGGGCTCGGC
ATCATCAAGTCGGCCGCCGAAATCGAGAAGCTCGCGGCGAGCGTGCCGCACACCGACGGCGTCTATCTGGTGCCGGCCTT
CGCCGGGCTCGGCGCGCCGCACTGGAACGCCCGCGCGCGCGGCTCGCTGTTCGGCGTCACGCGCGGCACCACCGATGCGC
ACCTGGCGCGCGCCGCGCTCGACGCGATCGCCTACCAGTCGCTCGACGTGCTCGCGGCGATGGAAGCCGATTCGGGCATC
AGCATCGGCGAGCTGCGCGTGGACGGCGGCGCGAGCGCGAACAACCTGCTGATGCAGTTCCAGGCCGATCTGCTCGGCGT
GGACGTGGTGCGCCCGCGCATCACCGAAACCACCGCGCTCGGCGCCGCGTATCTCGCCGGGCTCGCCACCGGCTACTGGC
AGAACATCGACGAGGTGCGCAGCCAGTGGAAGCTCGACCGGCGCTTCTCGCCGTCGCTGCCGTCCGACGAGGTGAGCGCG
GCGCTGGCCGGCTGGCAGCGCGCGGTGCGCGCCGCCAAGGCGTGGGCCGACGACGCGCAGTAA

Upstream 100 bases:

>100_bases
CGCGGGGCGCCGAGGGGCGCGCCGCGCGGCAGCGACAGCAGCACGCGCCGCCACCAGGGCGATGCGGATCACAATTACGC
ACCAAATGGAGATGAGACAG

Downstream 100 bases:

>100_bases
ACTGCGGGTCCGCCGCACGACCGCGGCGGCCGGCAGCGGGCAACACCACCACGATTCATAACGAGCAGGCGGACCGTGCA
GCGCGCGAGTCCGCCGCATT

Product: glycerol kinase

Products: NA

Alternate protein names: ATP:glycerol 3-phosphotransferase; Glycerokinase; GK [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPRPGWVEHDPHEIWSTQAGVAAEAVTRVGLNGTAIAAIGIT
NQRETTIVWDRETGQPIYNAIVWQDRRTADFCDALKADGLEAMVRAKTGLPIDSYFSGTKIRWILDNVEGAREKARQGRL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTRQWDDELLAALDIPRSMLPEVRASSEVYGHTKTTVFASKLPLAG
IAGDQQAALFGQMCTTKGMVKNTYGTGCFLVMNTGDTPIESSNNLVTTIAWQVGDQVNYALEGSIFIAGAVVQWLRDGLG
IIKSAAEIEKLAASVPHTDGVYLVPAFAGLGAPHWNARARGSLFGVTRGTTDAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANNLLMQFQADLLGVDVVRPRITETTALGAAYLAGLATGYWQNIDEVRSQWKLDRRFSPSLPSDEVSA
ALAGWQRAVRAAKAWADDAQ

Sequences:

>Translated_500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPRPGWVEHDPHEIWSTQAGVAAEAVTRVGLNGTAIAAIGIT
NQRETTIVWDRETGQPIYNAIVWQDRRTADFCDALKADGLEAMVRAKTGLPIDSYFSGTKIRWILDNVEGAREKARQGRL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTRQWDDELLAALDIPRSMLPEVRASSEVYGHTKTTVFASKLPLAG
IAGDQQAALFGQMCTTKGMVKNTYGTGCFLVMNTGDTPIESSNNLVTTIAWQVGDQVNYALEGSIFIAGAVVQWLRDGLG
IIKSAAEIEKLAASVPHTDGVYLVPAFAGLGAPHWNARARGSLFGVTRGTTDAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANNLLMQFQADLLGVDVVRPRITETTALGAAYLAGLATGYWQNIDEVRSQWKLDRRFSPSLPSDEVSA
ALAGWQRAVRAAKAWADDAQ
>Mature_500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPRPGWVEHDPHEIWSTQAGVAAEAVTRVGLNGTAIAAIGIT
NQRETTIVWDRETGQPIYNAIVWQDRRTADFCDALKADGLEAMVRAKTGLPIDSYFSGTKIRWILDNVEGAREKARQGRL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTRQWDDELLAALDIPRSMLPEVRASSEVYGHTKTTVFASKLPLAG
IAGDQQAALFGQMCTTKGMVKNTYGTGCFLVMNTGDTPIESSNNLVTTIAWQVGDQVNYALEGSIFIAGAVVQWLRDGLG
IIKSAAEIEKLAASVPHTDGVYLVPAFAGLGAPHWNARARGSLFGVTRGTTDAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANNLLMQFQADLLGVDVVRPRITETTALGAAYLAGLATGYWQNIDEVRSQWKLDRRFSPSLPSDEVSA
ALAGWQRAVRAAKAWADDAQ

Specific function: Key enzyme in the regulation of glycerol uptake and metabolism [H]

COG id: COG0554

COG function: function code C; Glycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI189409120, Length=501, Percent_Identity=45.7085828343313, Blast_Score=447, Evalue=1e-125,
Organism=Homo sapiens, GI4504007, Length=501, Percent_Identity=45.7085828343313, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI42794763, Length=506, Percent_Identity=45.8498023715415, Blast_Score=445, Evalue=1e-125,
Organism=Homo sapiens, GI41393575, Length=501, Percent_Identity=44.5109780439122, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI88196792, Length=510, Percent_Identity=32.156862745098, Blast_Score=309, Evalue=4e-84,
Organism=Escherichia coli, GI1790361, Length=497, Percent_Identity=60.5633802816901, Blast_Score=654, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=485, Percent_Identity=25.360824742268, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789168, Length=487, Percent_Identity=25.0513347022587, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789987, Length=480, Percent_Identity=23.3333333333333, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1787789, Length=481, Percent_Identity=25.1559251559252, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17535599, Length=500, Percent_Identity=44, Blast_Score=416, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI71986140, Length=517, Percent_Identity=24.3713733075435, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71986147, Length=258, Percent_Identity=30.2325581395349, Blast_Score=127, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6321755, Length=496, Percent_Identity=37.7016129032258, Blast_Score=303, Evalue=4e-83,
Organism=Drosophila melanogaster, GI17864214, Length=508, Percent_Identity=42.7165354330709, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24655555, Length=480, Percent_Identity=42.7083333333333, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655560, Length=480, Percent_Identity=42.7083333333333, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655570, Length=480, Percent_Identity=42.7083333333333, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655574, Length=480, Percent_Identity=42.7083333333333, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655565, Length=480, Percent_Identity=42.7083333333333, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24654573, Length=448, Percent_Identity=43.3035714285714, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19922058, Length=530, Percent_Identity=33.0188679245283, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24652871, Length=497, Percent_Identity=34.0040241448692, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24656367, Length=513, Percent_Identity=30.2144249512671, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI21357867, Length=525, Percent_Identity=29.1428571428571, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24656372, Length=367, Percent_Identity=29.9727520435967, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI45552909, Length=308, Percent_Identity=28.2467532467532, Blast_Score=130, Evalue=3e-30,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR005999 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.30 [H]

Molecular weight: Translated: 54385; Mature: 54385

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPRPGWVEHDPHEIWSTQAGVA
CCCCEEEEEECCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHH
AEAVTRVGLNGTAIAAIGITNQRETTIVWDRETGQPIYNAIVWQDRRTADFCDALKADGL
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEECCCCCHHHHHHHHCCCH
EAMVRAKTGLPIDSYFSGTKIRWILDNVEGAREKARQGRLAFGTVDSWLVWNFTKHELHV
HHHHHHHCCCCHHHCCCCCEEEEEEECCHHHHHHHHCCCEEEECCCCEEEEEEECCEEEE
TDVTNASRTMLFNIHTRQWDDELLAALDIPRSMLPEVRASSEVYGHTKTTVFASKLPLAG
EECCCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCEEEECCCCCCC
IAGDQQAALFGQMCTTKGMVKNTYGTGCFLVMNTGDTPIESSNNLVTTIAWQVGDQVNYA
CCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEE
LEGSIFIAGAVVQWLRDGLGIIKSAAEIEKLAASVPHTDGVYLVPAFAGLGAPHWNARAR
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCC
GSLFGVTRGTTDAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANNLLMQF
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCHHHHHHEE
QADLLGVDVVRPRITETTALGAAYLAGLATGYWQNIDEVRSQWKLDRRFSPSLPSDEVSA
HHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHH
ALAGWQRAVRAAKAWADDAQ
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPRPGWVEHDPHEIWSTQAGVA
CCCCEEEEEECCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHH
AEAVTRVGLNGTAIAAIGITNQRETTIVWDRETGQPIYNAIVWQDRRTADFCDALKADGL
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEECCCCCHHHHHHHHCCCH
EAMVRAKTGLPIDSYFSGTKIRWILDNVEGAREKARQGRLAFGTVDSWLVWNFTKHELHV
HHHHHHHCCCCHHHCCCCCEEEEEEECCHHHHHHHHCCCEEEECCCCEEEEEEECCEEEE
TDVTNASRTMLFNIHTRQWDDELLAALDIPRSMLPEVRASSEVYGHTKTTVFASKLPLAG
EECCCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCEEEECCCCCCC
IAGDQQAALFGQMCTTKGMVKNTYGTGCFLVMNTGDTPIESSNNLVTTIAWQVGDQVNYA
CCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEE
LEGSIFIAGAVVQWLRDGLGIIKSAAEIEKLAASVPHTDGVYLVPAFAGLGAPHWNARAR
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCC
GSLFGVTRGTTDAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANNLLMQF
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCHHHHHHEE
QADLLGVDVVRPRITETTALGAAYLAGLATGYWQNIDEVRSQWKLDRRFSPSLPSDEVSA
HHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHH
ALAGWQRAVRAAKAWADDAQ
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA