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The map label for this gene is glpR [H]

Identifier: 238028574

GI number: 238028574

Start: 3452641

End: 3453420

Strand: Direct

Name: glpR [H]

Synonym: bglu_1g30380

Alternate gene names: 238028574

Gene position: 3452641-3453420 (Clockwise)

Preceding gene: 238028570

Following gene: 238028575

Centisome position: 88.38

GC content: 67.44

Gene sequence:

>780_bases
ATGACACGAGACCCCCGCCTGTCGCTGAACGCCCGCCAGCAGGAACTGCTCGAATGGGTGCAGCGCGACGGCTTCGTCAC
CGTCGACGATCTCGCGACGCACTTCGACGTGACGCCTCAAACGATCCGCCGCGACGTGAACTGGCTCGCCGACCTGAACC
TGCTGCGCCGCTATCACGGCGGCGCGAGCCTGCCGACCAGCTCGGAAAACGTCTCGTACAGCGCCCGCCAGCGCATGTTC
CACGACGAGAAACGCCGCATCGCCGCGCTGGCGGCCTCGCACATCCCCGACCAGGCGTCGCTGTTCATCAATCTCGGCAC
CACCACCGAGGAGGTCGCGCGCGCGCTGAACCGCCACCGCGGCCTGCGGGTGGTCACCAACAACCTGAACGTGGCGAGCA
TGATGAGCGGCTATCCCGAGTGCGAGGTGCTGATCACCGGCGGCATCGTGCGGCCCTGGGACAAGGGCATCGTCGGCGAG
CTCGCGATCGACTTCATCCGCCAGTTCAAGGTGGACTACGCGATCATCGGCACCTCGGCGATCGAGACCGACGGCACGAT
GCGCGACTTCGATACGCGCGAGGTGCGCGTCGCCGAGGCGATCATGCAGCACGCGCGCACCGTCTATCTCGTCACCGACC
ACTCGAAGTTCGGGCGCCCCGCGCTGGTGCGTCAGGGCCACCTGTCGCAGGTACACGCGCTGTTCACCGACAAGGCGCTG
CCCGCCGAGATGGGCGATACGATCGCCGCGGCCGGCACGCAGGTCTACATCGCCGACTGA

Upstream 100 bases:

>100_bases
AGCGGGGCATCGGTATCGGGCGGGCGCGCGCGAAAACGGAATGTTCGTTCGCGCACATTGCTTACAATACGGAACCCGCT
TCCCGAGCCTTCGAACGAAC

Downstream 100 bases:

>100_bases
ACCCGTCCCTGGCGCGCGGCGGCGCGCACGGCGATCCCCCCGCCGGCAGCGCGCGCGCCGTGCTGCGTCGCAGCGTGAAC
TTGAAGTGAAATCAAGAAGT

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTRDPRLSLNARQQELLEWVQRDGFVTVDDLATHFDVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYSARQRMF
HDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHRGLRVVTNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGE
LAIDFIRQFKVDYAIIGTSAIETDGTMRDFDTREVRVAEAIMQHARTVYLVTDHSKFGRPALVRQGHLSQVHALFTDKAL
PAEMGDTIAAAGTQVYIAD

Sequences:

>Translated_259_residues
MTRDPRLSLNARQQELLEWVQRDGFVTVDDLATHFDVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYSARQRMF
HDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHRGLRVVTNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGE
LAIDFIRQFKVDYAIIGTSAIETDGTMRDFDTREVRVAEAIMQHARTVYLVTDHSKFGRPALVRQGHLSQVHALFTDKAL
PAEMGDTIAAAGTQVYIAD
>Mature_258_residues
TRDPRLSLNARQQELLEWVQRDGFVTVDDLATHFDVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYSARQRMFH
DEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHRGLRVVTNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGEL
AIDFIRQFKVDYAIIGTSAIETDGTMRDFDTREVRVAEAIMQHARTVYLVTDHSKFGRPALVRQGHLSQVHALFTDKALP
AEMGDTIAAAGTQVYIAD

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=233, Percent_Identity=46.7811158798283, Blast_Score=227, Evalue=5e-61,
Organism=Escherichia coli, GI87082344, Length=238, Percent_Identity=40.7563025210084, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=30.3418803418803, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=29.8387096774194, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790753, Length=249, Percent_Identity=26.9076305220884, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=26.5060240963855, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI226510968, Length=231, Percent_Identity=29.8701298701299, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=235, Percent_Identity=29.7872340425532, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787063, Length=240, Percent_Identity=29.5833333333333, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790635, Length=139, Percent_Identity=31.6546762589928, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=23.3766233766234, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28972; Mature: 28841

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDPRLSLNARQQELLEWVQRDGFVTVDDLATHFDVTPQTIRRDVNWLADLNLLRRYHG
CCCCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
GASLPTSSENVSYSARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCC
GLRVVTNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSA
CEEEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCE
IETDGTMRDFDTREVRVAEAIMQHARTVYLVTDHSKFGRPALVRQGHLSQVHALFTDKAL
ECCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHCCCC
PAEMGDTIAAAGTQVYIAD
CHHHCCCEECCCCEEEEEC
>Mature Secondary Structure 
TRDPRLSLNARQQELLEWVQRDGFVTVDDLATHFDVTPQTIRRDVNWLADLNLLRRYHG
CCCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
GASLPTSSENVSYSARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCC
GLRVVTNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSA
CEEEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCE
IETDGTMRDFDTREVRVAEAIMQHARTVYLVTDHSKFGRPALVRQGHLSQVHALFTDKAL
ECCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHCCCC
PAEMGDTIAAAGTQVYIAD
CHHHCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]