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The map label for this gene is pgk [H]

Identifier: 238028514

GI number: 238028514

Start: 3373085

End: 3374281

Strand: Reverse

Name: pgk [H]

Synonym: bglu_1g29780

Alternate gene names: 238028514

Gene position: 3374281-3373085 (Counterclockwise)

Preceding gene: 238028515

Following gene: 238028513

Centisome position: 86.38

GC content: 68.84

Gene sequence:

>1197_bases
ATGAGCCAAGTAAAGCGTCTTACCGACCTGATCGCCGAAGGCAAAGTCTCCGGCCAACGCGTGTTCATCCGCGCCGATCT
GAACGTGCCGCAGGACGACCACGGCAACATCACCGAGGACACGCGCGTGCGCGCCTCGGTGCCGGCGATCAAGGCGGCGC
TCGACGCGGGCGCGGCGGTGATGGTCACCTCGCACCTGGGCCGTCCGACGGAAGGCGAGCTCAAGCCCGAGGATTCGCTC
GCGCCGGTGGCCCGGCGCCTCGCCGAGCTGCTCGGCCGCGACGTGCCGCTGGTGTCGAACTGGGTCGAGAACGGCGTGAA
CGTGACGCCGGGCAACGTCGTGCTGCTCGAGAACTGCCGCGTGAACAAGGGCGAGAAGAAGAACGACGACGCGCTCGCGC
AGAAGATGGCCAAGCTCTGCGACATCTACGTCAACGACGCGTTCGGCACCGCGCACCGCGCCGAGGCCACCACCCACGGC
ATCGCCAAATATGCCGGCATCGCCTGCGCGGGCCCGCTGCTCGCCGCCGAGCTCGACGCGCTCGGCAAGGCGCTCGGCAA
TCCGAAGCGGCCGCTGGTGGCGATCGTCGCCGGCTCGAAGGTGTCCACCAAGCTGACCATCCTGAAGTCGCTGGCCGAGA
AGGTCGACCAGCTGATCGTCGGCGGCGGCATCGCCAACACCTTCATGCTCGCCGCCGGCCTCACGATCGGCAAGTCGCTG
GCCGAGCCGGACCTCGTCGACGAGGCGCGGACCATCATCGACGAGGCCCGCAAGCGCGGCGCATCGGTGCCGATCCCGTC
GGACGTGGTCACGGCCAAGCAATTCGCCGCCACCGCCCAGGCCACCGTCAAGCAAGTCGGCGAGATCGAGGCGGACGACC
TGATCCTCGACATCGGCCCGGAAACGGCCAAGGCGCTCGCCGGCCAGCTCGAGAAGGCCGGCACCATCGTCTGGAACGGG
CCGGTCGGCGTGTTCGAGTTCGACCAGTTCGGCAACGGCACCAAGACGCTCGCCGAGGCGATCGCGAATTCGCCGGCGTT
CTCGATCGCCGGCGGCGGCGACACGCTCGCCGCGATCGCCAAGTACGGCATCCACGACAAGGTCAGCTATATCTCCACCG
GCGGCGGCGCGTTCCTCGAGTTCCTCGAGGGCAAGACGCTGCCGGCCGTGGAGGTGCTGGAAACGCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
GAACGTGTCGCACGGCCCAGCCCGGCCGTCCGGCGCCCCCGTCGGCAGCCCGCGCGCGAGGTTTCAGCACCGCCTTCCTC
ATCAACCTTCAATCAGTCCC

Downstream 100 bases:

>100_bases
GATGGCGCGAGGCCGCGCGGCAGCAAGCCGGAAGGCGGCGGGGGCGGCGCGCTCGCGCCCCGGACCGCGCGCCGGCGCCC
GGCCGGAGCGCGTCGCCCCC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSQVKRLTDLIAEGKVSGQRVFIRADLNVPQDDHGNITEDTRVRASVPAIKAALDAGAAVMVTSHLGRPTEGELKPEDSL
APVARRLAELLGRDVPLVSNWVENGVNVTPGNVVLLENCRVNKGEKKNDDALAQKMAKLCDIYVNDAFGTAHRAEATTHG
IAKYAGIACAGPLLAAELDALGKALGNPKRPLVAIVAGSKVSTKLTILKSLAEKVDQLIVGGGIANTFMLAAGLTIGKSL
AEPDLVDEARTIIDEARKRGASVPIPSDVVTAKQFAATAQATVKQVGEIEADDLILDIGPETAKALAGQLEKAGTIVWNG
PVGVFEFDQFGNGTKTLAEAIANSPAFSIAGGGDTLAAIAKYGIHDKVSYISTGGGAFLEFLEGKTLPAVEVLETRGA

Sequences:

>Translated_398_residues
MSQVKRLTDLIAEGKVSGQRVFIRADLNVPQDDHGNITEDTRVRASVPAIKAALDAGAAVMVTSHLGRPTEGELKPEDSL
APVARRLAELLGRDVPLVSNWVENGVNVTPGNVVLLENCRVNKGEKKNDDALAQKMAKLCDIYVNDAFGTAHRAEATTHG
IAKYAGIACAGPLLAAELDALGKALGNPKRPLVAIVAGSKVSTKLTILKSLAEKVDQLIVGGGIANTFMLAAGLTIGKSL
AEPDLVDEARTIIDEARKRGASVPIPSDVVTAKQFAATAQATVKQVGEIEADDLILDIGPETAKALAGQLEKAGTIVWNG
PVGVFEFDQFGNGTKTLAEAIANSPAFSIAGGGDTLAAIAKYGIHDKVSYISTGGGAFLEFLEGKTLPAVEVLETRGA
>Mature_397_residues
SQVKRLTDLIAEGKVSGQRVFIRADLNVPQDDHGNITEDTRVRASVPAIKAALDAGAAVMVTSHLGRPTEGELKPEDSLA
PVARRLAELLGRDVPLVSNWVENGVNVTPGNVVLLENCRVNKGEKKNDDALAQKMAKLCDIYVNDAFGTAHRAEATTHGI
AKYAGIACAGPLLAAELDALGKALGNPKRPLVAIVAGSKVSTKLTILKSLAEKVDQLIVGGGIANTFMLAAGLTIGKSLA
EPDLVDEARTIIDEARKRGASVPIPSDVVTAKQFAATAQATVKQVGEIEADDLILDIGPETAKALAGQLEKAGTIVWNGP
VGVFEFDQFGNGTKTLAEAIANSPAFSIAGGGDTLAAIAKYGIHDKVSYISTGGGAFLEFLEGKTLPAVEVLETRGA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=421, Percent_Identity=41.3301662707838, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI4505763, Length=408, Percent_Identity=41.1764705882353, Blast_Score=274, Evalue=9e-74,
Organism=Escherichia coli, GI1789294, Length=396, Percent_Identity=61.6161616161616, Blast_Score=463, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17508823, Length=420, Percent_Identity=42.1428571428571, Blast_Score=292, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6319857, Length=403, Percent_Identity=41.6873449131514, Blast_Score=269, Evalue=6e-73,
Organism=Drosophila melanogaster, GI17136394, Length=408, Percent_Identity=39.7058823529412, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24581203, Length=418, Percent_Identity=38.0382775119617, Blast_Score=241, Evalue=6e-64,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 41425; Mature: 41294

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVKRLTDLIAEGKVSGQRVFIRADLNVPQDDHGNITEDTRVRASVPAIKAALDAGAAV
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
MVTSHLGRPTEGELKPEDSLAPVARRLAELLGRDVPLVSNWVENGVNVTPGNVVLLENCR
EEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
VNKGEKKNDDALAQKMAKLCDIYVNDAFGTAHRAEATTHGIAKYAGIACAGPLLAAELDA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKALGNPKRPLVAIVAGSKVSTKLTILKSLAEKVDQLIVGGGIANTFMLAAGLTIGKSL
HHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AEPDLVDEARTIIDEARKRGASVPIPSDVVTAKQFAATAQATVKQVGEIEADDLILDIGP
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
ETAKALAGQLEKAGTIVWNGPVGVFEFDQFGNGTKTLAEAIANSPAFSIAGGGDTLAAIA
HHHHHHHHHHHHCCEEEECCCCCEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHH
KYGIHDKVSYISTGGGAFLEFLEGKTLPAVEVLETRGA
HHCCCCCHHHEECCCHHHHHHHCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SQVKRLTDLIAEGKVSGQRVFIRADLNVPQDDHGNITEDTRVRASVPAIKAALDAGAAV
CHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
MVTSHLGRPTEGELKPEDSLAPVARRLAELLGRDVPLVSNWVENGVNVTPGNVVLLENCR
EEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
VNKGEKKNDDALAQKMAKLCDIYVNDAFGTAHRAEATTHGIAKYAGIACAGPLLAAELDA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKALGNPKRPLVAIVAGSKVSTKLTILKSLAEKVDQLIVGGGIANTFMLAAGLTIGKSL
HHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AEPDLVDEARTIIDEARKRGASVPIPSDVVTAKQFAATAQATVKQVGEIEADDLILDIGP
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
ETAKALAGQLEKAGTIVWNGPVGVFEFDQFGNGTKTLAEAIANSPAFSIAGGGDTLAAIA
HHHHHHHHHHHHCCEEEECCCCCEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHH
KYGIHDKVSYISTGGGAFLEFLEGKTLPAVEVLETRGA
HHCCCCCHHHEECCCHHHHHHHCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]