Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 238028502

GI number: 238028502

Start: 3358492

End: 3359982

Strand: Reverse

Name: degP [H]

Synonym: bglu_1g29660

Alternate gene names: 238028502

Gene position: 3359982-3358492 (Counterclockwise)

Preceding gene: 238028503

Following gene: 238028501

Centisome position: 86.01

GC content: 68.41

Gene sequence:

>1491_bases
ATGAAGACTCGTTTCCTGGCGCGCAGCGCCGTCGCCGTGGCCGTCGCGGCCGCATTGTCAGCAGGTTATGTCGCCGGCAC
GCGTCACGCGCAGCCCCCCCAGATCATCACGCCGGCCTCGGCCGCCGCGCTGATGCCGGCTGAGGCCGCCGCCAAGACCG
GCATTCCGGACTTCTCCGGGCTGGTCGAGACCTACGGCCCGGCCGTGGTCAACATCAGCGCGAAGCACGTCGTGAAGGCG
TCGGCGCGGCGCGGCGGCGGTGGTCCGCAGCAACTGCCGATCGACCCGAGCGATCCGTTCTACCAGTTCTTCAAGCATTT
CTACGGCCAGGTGCCGGGCATGGGCGGCGGCCAGACCGACGACCAGCCGAGCACGAGCCTCGGCTCGGGCTTCATCGTCA
GCCCGGACGGCTACATCCTTACCAACGCTCACGTGATCGACGGCGCCAACGTGATCACCGTCAAGCTGACCGACAAGCGC
GAGTATCGTGCCAAGGTGATCGGCTCGGACAAGCAGTCCGACGTCGCGGTGCTGAAGATCGATGCCACCGGCCTGCCGGT
CGTGAAGATCGGCGATCCGCAGCAGAGCAAGGTGGGCCAGTGGGTGGTGGCGATCGGCTCGCCCTACGGCTTCGACAACA
CCGTCACCTCGGGCATCATCAGCGCCAAGTCGCGCGCGTTGCCCGACGAGAACTACACGCCGTTCATCCAGACCGACGTG
CCGGTCAACCCCGGCAACTCGGGCGGCCCGCTGTTCAACCTGCAGGGCGAGGTGATCGGCATCAATTCGATGATCTACTC
GCAGACGGGCGGCTTCCAGGGCCTGTCGTTCGCGATTCCGATCAACGAGGCGATCAAGGTCAAGGATGAGCTCGTGAAGA
CCGGCCACGTCAGCCGCGGCCGGCTCGGCGTGGCGGTGCAGGGCCTCGACCAGACGCTGGCCAGCTCGTTCGGGCTGCCG
AAACCCGACGGCGCGCTGGTCAGCTCGGTCGATCCGAAGGGGCCGGCCGCGAAGGCGGGCCTGCAGCCCGGCGACGTGAT
CCTGGCGGTCAACGGCGTGCCGGTGCAGGACTCCACCATGCTACCGGGACAGATCGCGAGCCTGAAACCGGGCACCAAGG
CCGAGCTGCAGATCTGGCGCGACAAGTCGAAGAAGGACGTGTCGGTGACGCTGGCCTCGCTGGCCGATAGCCAGCAGACC
GCCAGCAACGACGGTCCTGCCGAGCAGGGGCGCCTGGGCGTGGCGGTGCGGCAACTGACCCCGCAGGAACGCGCCGGCAC
CTCGCTCACGCACGGGCTGGTGGTGCAGCAGGCGACCGGGCCGGCCGCCAACGCCGGGATCCAGCCGGGCGACGTGATCC
TTGCCGTGAACGGCCGGCCGGTGACGAGCGCCGAGCAGCTGCGCGATGCGGTGAAGAGCGCCGGCAACAGCCTCGCGCTG
CTGATCCAGCGCGACAACGCGCAGATCTTCGTGCCGGTTGATCTGAGCTGA

Upstream 100 bases:

>100_bases
AATGCCGCCCGGCCTGGCCTTTGGCTCTGGCCCCGGTTCGGTTAAGCCTCCTTTAAGACAGCGTCGTTACGCTGCGAACC
AACATGAGGAGGTAGTGACG

Downstream 100 bases:

>100_bases
GCGGATGAAGGCCGCCGCTGCCGGCGCCGCCCCGTCTGTGCCAAGCTACGCTCGGGCCGGATGGCGCGCTGGCGTCCGCT
CCGGCCAGATCACGCGGCGG

Product: Protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MKTRFLARSAVAVAVAAALSAGYVAGTRHAQPPQIITPASAAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKA
SARRGGGGPQQLPIDPSDPFYQFFKHFYGQVPGMGGGQTDDQPSTSLGSGFIVSPDGYILTNAHVIDGANVITVKLTDKR
EYRAKVIGSDKQSDVAVLKIDATGLPVVKIGDPQQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDV
PVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRLGVAVQGLDQTLASSFGLP
KPDGALVSSVDPKGPAAKAGLQPGDVILAVNGVPVQDSTMLPGQIASLKPGTKAELQIWRDKSKKDVSVTLASLADSQQT
ASNDGPAEQGRLGVAVRQLTPQERAGTSLTHGLVVQQATGPAANAGIQPGDVILAVNGRPVTSAEQLRDAVKSAGNSLAL
LIQRDNAQIFVPVDLS

Sequences:

>Translated_496_residues
MKTRFLARSAVAVAVAAALSAGYVAGTRHAQPPQIITPASAAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKA
SARRGGGGPQQLPIDPSDPFYQFFKHFYGQVPGMGGGQTDDQPSTSLGSGFIVSPDGYILTNAHVIDGANVITVKLTDKR
EYRAKVIGSDKQSDVAVLKIDATGLPVVKIGDPQQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDV
PVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRLGVAVQGLDQTLASSFGLP
KPDGALVSSVDPKGPAAKAGLQPGDVILAVNGVPVQDSTMLPGQIASLKPGTKAELQIWRDKSKKDVSVTLASLADSQQT
ASNDGPAEQGRLGVAVRQLTPQERAGTSLTHGLVVQQATGPAANAGIQPGDVILAVNGRPVTSAEQLRDAVKSAGNSLAL
LIQRDNAQIFVPVDLS
>Mature_496_residues
MKTRFLARSAVAVAVAAALSAGYVAGTRHAQPPQIITPASAAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKA
SARRGGGGPQQLPIDPSDPFYQFFKHFYGQVPGMGGGQTDDQPSTSLGSGFIVSPDGYILTNAHVIDGANVITVKLTDKR
EYRAKVIGSDKQSDVAVLKIDATGLPVVKIGDPQQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDV
PVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRGRLGVAVQGLDQTLASSFGLP
KPDGALVSSVDPKGPAAKAGLQPGDVILAVNGVPVQDSTMLPGQIASLKPGTKAELQIWRDKSKKDVSVTLASLADSQQT
ASNDGPAEQGRLGVAVRQLTPQERAGTSLTHGLVVQQATGPAANAGIQPGDVILAVNGRPVTSAEQLRDAVKSAGNSLAL
LIQRDNAQIFVPVDLS

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=241, Percent_Identity=39.0041493775934, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI22129776, Length=265, Percent_Identity=36.9811320754717, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI24308541, Length=251, Percent_Identity=37.0517928286853, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI7019477, Length=283, Percent_Identity=35.6890459363958, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1786356, Length=463, Percent_Identity=36.9330453563715, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1789629, Length=500, Percent_Identity=36, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=39.4833948339483, Blast_Score=184, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24646839, Length=263, Percent_Identity=37.6425855513308, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51208; Mature: 51208

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRFLARSAVAVAVAAALSAGYVAGTRHAQPPQIITPASAAALMPAEAAAKTGIPDFSG
CCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEECCCCHHHHCCHHHHHHCCCCCHHH
LVETYGPAVVNISAKHVVKASARRGGGGPQQLPIDPSDPFYQFFKHFYGQVPGMGGGQTD
HHHHCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
DQPSTSLGSGFIVSPDGYILTNAHVIDGANVITVKLTDKREYRAKVIGSDKQSDVAVLKI
CCCCCCCCCCEEECCCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEE
DATGLPVVKIGDPQQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDV
CCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECC
PVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRG
CCCCCCCCCCEEEECCCEEEECEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC
RLGVAVQGLDQTLASSFGLPKPDGALVSSVDPKGPAAKAGLQPGDVILAVNGVPVQDSTM
EEEEEEECHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCC
LPGQIASLKPGTKAELQIWRDKSKKDVSVTLASLADSQQTASNDGPAEQGRLGVAVRQLT
CCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEHHHCCHHHCCCCCCHHCCCEEEEEECCC
PQERAGTSLTHGLVVQQATGPAANAGIQPGDVILAVNGRPVTSAEQLRDAVKSAGNSLAL
CHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEE
LIQRDNAQIFVPVDLS
EEEECCCEEEEEEECC
>Mature Secondary Structure
MKTRFLARSAVAVAVAAALSAGYVAGTRHAQPPQIITPASAAALMPAEAAAKTGIPDFSG
CCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEECCCCHHHHCCHHHHHHCCCCCHHH
LVETYGPAVVNISAKHVVKASARRGGGGPQQLPIDPSDPFYQFFKHFYGQVPGMGGGQTD
HHHHCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
DQPSTSLGSGFIVSPDGYILTNAHVIDGANVITVKLTDKREYRAKVIGSDKQSDVAVLKI
CCCCCCCCCCEEECCCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEE
DATGLPVVKIGDPQQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDV
CCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECC
PVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDELVKTGHVSRG
CCCCCCCCCCEEEECCCEEEECEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC
RLGVAVQGLDQTLASSFGLPKPDGALVSSVDPKGPAAKAGLQPGDVILAVNGVPVQDSTM
EEEEEEECHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCC
LPGQIASLKPGTKAELQIWRDKSKKDVSVTLASLADSQQTASNDGPAEQGRLGVAVRQLT
CCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEHHHCCHHHCCCCCCHHCCCEEEEEECCC
PQERAGTSLTHGLVVQQATGPAANAGIQPGDVILAVNGRPVTSAEQLRDAVKSAGNSLAL
CHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEE
LIQRDNAQIFVPVDLS
EEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]