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The map label for this gene is mco [H]

Identifier: 238028420

GI number: 238028420

Start: 3268214

End: 3269809

Strand: Reverse

Name: mco [H]

Synonym: bglu_1g28840

Alternate gene names: 238028420

Gene position: 3269809-3268214 (Counterclockwise)

Preceding gene: 238028421

Following gene: 238028418

Centisome position: 83.7

GC content: 72.99

Gene sequence:

>1596_bases
ATGATACGCAGGCAATTTCTCCGCCGCGCGCTCGGCGCGGCGGCTTCGCTCGCCTTCGCGCGCGGCGCGCTCGCGAAGGT
GCCGGCGGCGGAGGCGCCGCATGCCATGGAGCAGATGAGCGGCATGGCGGGCATGCATGCGGCGCCGGACGCGGCGGGGC
CCGCCGGTGGCGGCACGCTCGCGGCTGCCGACGCGCTGCCGGCCGGCGCGCCGCTCGCGCCGCTGCGCGTGCTCGCCAAC
GAGAGCACGACGCCGGGGCAATTCCGCGCGACGCTCGTGGCGCAGCCGGTCGCGCGGCAGCTATTGCCCGGCGCGGCACC
CACCGGCATGTGGCTCTACGGCGACGCGGCGACGGGTGCCGTGGTGGGGCCGCTGATCGAGCTGCACGAGGGCGACGCCG
TCGAGATCCGTGTCGTCAACCACCTGCCGCAGCCGACCACGGTCCACTGGCATGGCCTGCCGGTGCCGCCCGACCAGGAC
GGCAACCCGCTCGCGCTGATCGCGCCCGGCGCTTCGCGCACCTATCGCTTCACGTTGCCGAAAGGCAGCGCCGGCACCTA
CTGGTATCACCCTCATCCGCACATGATGACGGCCGAGCAGGTGTTTCGCGGCCTGGCCGGGCCGCTCGTGGTGCGCGCGG
CCGACGATCCGCTCGCCGGCTGGCCCGAGCGCCAGCTGTTCGTGTCGGACCTGAAGCTGGCGGCCGATGGCGCGATCGCC
CCGAACGACATGATGGACTGGATGAACGGCCGCGAAGGCCAGTTCGTGCTGGTCAACGGCGCGCGCCGCCCGCGCCTGGA
GGTGGCAGGCGACGAGCGCTGGCGTGTCTGGAACGGCTGCAGCGCGCGCTTCCTGAACCTGTGCTTCGACGACGGCCGCG
CCTTCGAACAGGTCGGCACCGACGGTGGCCTGTTCGAGCGGCCGCGCCGCGTGACCGCGCTGCTGCTCGCGCCGGGCGAG
CGCGCCGAATTGCTGGTGCGCGCCGGCGAGCATGCCTCGCGCGCGGTGCTGCGCGCGGCCACCTACGACCGCAGCAAGAT
GGCCATGGCCATGTCGGCCGACGAGGATGCCTCGCTGCCGCCCGATCCGCCGCTTCCGCTCGCGGACCTCAGCTTCGCGC
CGGCGCCGGCGCGCGAGGTGCCCGCCGCGCTGCGCGCGGTGCCGGCGCTCGGCACGCCGGTGGCGCGCAAGTCGGTTACG
TTCGGCGAGGCGATGGACATGGACGCGATGATGGCCTCGGCGCCGGGCACCCGCCCGGCCGGCATGCGCTTCCTCGTGAA
CGGGCAGACCTGGTCGCCGCATCGCGCGACGCTCACGAGCCGGCGCGGCGAGGTCGAACTGTGGACCATCACCAACACCA
CCGACATGGACCACCCGTTCCATCTGCACGGCACGCAGTTCCAGGTGCTCGAGCGCGAACTGCGCGGGCAGCGCACGCCG
GAGCCGTTCCGCGCCTGGCGCGACACCGTCAACGTCAGGAAGGGCGAGACGGTGCGGATCGCCACGGTCCAGCACCAGGC
CGGCGAGCGGATGTTCCACTGCCATATCCTCGAACACGAGGATCTCGGCATGATGGGCACCTTGAAGGTCGTCTGA

Upstream 100 bases:

>100_bases
TTCCGCAAGCTCGCCGTCTGACGCGAAACGGCGCGTGCGCCGCTGCAGCGGTGCACGCGCCGGTGTATCGTCATCGCTTC
GCTGACAGGGGAGTCGATCG

Downstream 100 bases:

>100_bases
GGCGCGGCGGCCGAGCATGGCCGCCGCCGAACGGCGAAGAGGCCGACGCCGATGGGGCCGGCGAAAAAAAACCCGGCTCG
GAGCCGGGTTTTTATCGAGA

Product: multicopper oxidase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MIRRQFLRRALGAAASLAFARGALAKVPAAEAPHAMEQMSGMAGMHAAPDAAGPAGGGTLAAADALPAGAPLAPLRVLAN
ESTTPGQFRATLVAQPVARQLLPGAAPTGMWLYGDAATGAVVGPLIELHEGDAVEIRVVNHLPQPTTVHWHGLPVPPDQD
GNPLALIAPGASRTYRFTLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPLVVRAADDPLAGWPERQLFVSDLKLAADGAIA
PNDMMDWMNGREGQFVLVNGARRPRLEVAGDERWRVWNGCSARFLNLCFDDGRAFEQVGTDGGLFERPRRVTALLLAPGE
RAELLVRAGEHASRAVLRAATYDRSKMAMAMSADEDASLPPDPPLPLADLSFAPAPAREVPAALRAVPALGTPVARKSVT
FGEAMDMDAMMASAPGTRPAGMRFLVNGQTWSPHRATLTSRRGEVELWTITNTTDMDHPFHLHGTQFQVLERELRGQRTP
EPFRAWRDTVNVRKGETVRIATVQHQAGERMFHCHILEHEDLGMMGTLKVV

Sequences:

>Translated_531_residues
MIRRQFLRRALGAAASLAFARGALAKVPAAEAPHAMEQMSGMAGMHAAPDAAGPAGGGTLAAADALPAGAPLAPLRVLAN
ESTTPGQFRATLVAQPVARQLLPGAAPTGMWLYGDAATGAVVGPLIELHEGDAVEIRVVNHLPQPTTVHWHGLPVPPDQD
GNPLALIAPGASRTYRFTLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPLVVRAADDPLAGWPERQLFVSDLKLAADGAIA
PNDMMDWMNGREGQFVLVNGARRPRLEVAGDERWRVWNGCSARFLNLCFDDGRAFEQVGTDGGLFERPRRVTALLLAPGE
RAELLVRAGEHASRAVLRAATYDRSKMAMAMSADEDASLPPDPPLPLADLSFAPAPAREVPAALRAVPALGTPVARKSVT
FGEAMDMDAMMASAPGTRPAGMRFLVNGQTWSPHRATLTSRRGEVELWTITNTTDMDHPFHLHGTQFQVLERELRGQRTP
EPFRAWRDTVNVRKGETVRIATVQHQAGERMFHCHILEHEDLGMMGTLKVV
>Mature_531_residues
MIRRQFLRRALGAAASLAFARGALAKVPAAEAPHAMEQMSGMAGMHAAPDAAGPAGGGTLAAADALPAGAPLAPLRVLAN
ESTTPGQFRATLVAQPVARQLLPGAAPTGMWLYGDAATGAVVGPLIELHEGDAVEIRVVNHLPQPTTVHWHGLPVPPDQD
GNPLALIAPGASRTYRFTLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPLVVRAADDPLAGWPERQLFVSDLKLAADGAIA
PNDMMDWMNGREGQFVLVNGARRPRLEVAGDERWRVWNGCSARFLNLCFDDGRAFEQVGTDGGLFERPRRVTALLLAPGE
RAELLVRAGEHASRAVLRAATYDRSKMAMAMSADEDASLPPDPPLPLADLSFAPAPAREVPAALRAVPALGTPVARKSVT
FGEAMDMDAMMASAPGTRPAGMRFLVNGQTWSPHRATLTSRRGEVELWTITNTTDMDHPFHLHGTQFQVLERELRGQRTP
EPFRAWRDTVNVRKGETVRIATVQHQAGERMFHCHILEHEDLGMMGTLKVV

Specific function: May be involved in copper homeostasis and oxidative stress response [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=457, Percent_Identity=33.0415754923414, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1789394, Length=430, Percent_Identity=29.3023255813954, Blast_Score=122, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24650186, Length=544, Percent_Identity=23.8970588235294, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859919, Length=502, Percent_Identity=24.7011952191235, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR002355
- InterPro:   IPR008972 [H]

Pfam domain/function: PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 57202; Mature: 57202

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRQFLRRALGAAASLAFARGALAKVPAAEAPHAMEQMSGMAGMHAAPDAAGPAGGGTL
CCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCE
AAADALPAGAPLAPLRVLANESTTPGQFRATLVAQPVARQLLPGAAPTGMWLYGDAATGA
EECCCCCCCCCCCHHHEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCCEEEEECCCCCH
VVGPLIELHEGDAVEIRVVNHLPQPTTVHWHGLPVPPDQDGNPLALIAPGASRTYRFTLP
HHHHHHEECCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEEEECC
KGSAGTYWYHPHPHMMTAEQVFRGLAGPLVVRAADDPLAGWPERQLFVSDLKLAADGAIA
CCCCCCEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCHHEEHHHHHEECCCCCC
PNDMMDWMNGREGQFVLVNGARRPRLEVAGDERWRVWNGCSARFLNLCFDDGRAFEQVGT
CHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEECCCCHHEEEEECCCCCHHHHCCC
DGGLFERPRRVTALLLAPGERAELLVRAGEHASRAVLRAATYDRSKMAMAMSADEDASLP
CCCHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
PDPPLPLADLSFAPAPAREVPAALRAVPALGTPVARKSVTFGEAMDMDAMMASAPGTRPA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCC
GMRFLVNGQTWSPHRATLTSRRGEVELWTITNTTDMDHPFHLHGTQFQVLERELRGQRTP
CEEEEEECCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCCCC
EPFRAWRDTVNVRKGETVRIATVQHQAGERMFHCHILEHEDLGMMGTLKVV
HHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MIRRQFLRRALGAAASLAFARGALAKVPAAEAPHAMEQMSGMAGMHAAPDAAGPAGGGTL
CCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCE
AAADALPAGAPLAPLRVLANESTTPGQFRATLVAQPVARQLLPGAAPTGMWLYGDAATGA
EECCCCCCCCCCCHHHEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCCEEEEECCCCCH
VVGPLIELHEGDAVEIRVVNHLPQPTTVHWHGLPVPPDQDGNPLALIAPGASRTYRFTLP
HHHHHHEECCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEEEECC
KGSAGTYWYHPHPHMMTAEQVFRGLAGPLVVRAADDPLAGWPERQLFVSDLKLAADGAIA
CCCCCCEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCHHEEHHHHHEECCCCCC
PNDMMDWMNGREGQFVLVNGARRPRLEVAGDERWRVWNGCSARFLNLCFDDGRAFEQVGT
CHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEECCCCHHEEEEECCCCCHHHHCCC
DGGLFERPRRVTALLLAPGERAELLVRAGEHASRAVLRAATYDRSKMAMAMSADEDASLP
CCCHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
PDPPLPLADLSFAPAPAREVPAALRAVPALGTPVARKSVTFGEAMDMDAMMASAPGTRPA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCC
GMRFLVNGQTWSPHRATLTSRRGEVELWTITNTTDMDHPFHLHGTQFQVLERELRGQRTP
CEEEEEECCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCCCC
EPFRAWRDTVNVRKGETVRIATVQHQAGERMFHCHILEHEDLGMMGTLKVV
HHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA