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The map label for this gene is ispH1 [H]

Identifier: 238028401

GI number: 238028401

Start: 3247333

End: 3248313

Strand: Reverse

Name: ispH1 [H]

Synonym: bglu_1g28650

Alternate gene names: 238028401

Gene position: 3248313-3247333 (Counterclockwise)

Preceding gene: 238028402

Following gene: 238028400

Centisome position: 83.15

GC content: 67.99

Gene sequence:

>981_bases
ATGAGCTCCACCGATACGCTGTCCGGCCCCACCGTCGCGGCCGATGCCGAAATCCTGCTCGCCCAGCCGCGCGGCTTCTG
CGCCGGCGTCGACCGCGCGATCGAGATCGTCGAGCGCGCGATCGCGATGCATGGTTCGCCGATCTACGTGCGCCACGAGA
TCGTGCACAACAAGTACGTGGTCGAGGATCTGAAGACGAAGGGCGCGATCTTCGTCGAGGAGCTCGAGGAAGTGCCGTCG
GGCAACACGGTGATCTTCAGCGCGCACGGCGTGTCGAAGGCGGTGCGCGACGAGGCCGCGGTGCGCGGCCTGCGCATCTA
CGACGCGACCTGCCCGCTCGTCACGAAGGTCCACGTCGAAGTCGCGAAGATGCGCCAGGACGGCGTGGACATCGTCATGA
TCGGCCACAAGGGGCATCCCGAGGTCGAGGGCACGATGGGGCAGGTCGAGCGCGGCATGCATCTGGTCGAGAGTGTCGAG
GACGTGCTGGCGCTGGAGTTGCCCGATCCCGAGCGCGTCGCGCTCGTCACGCAGACCACGCTGTCGGTCGACGATGCGGC
CGAGATCATCGCGGCGCTCAAGCGCAAGTTTCCGGCGATCCGCGAGCCGAAGAAGCAGGACATCTGCTACGCGACGCAGA
ACCGCCAGGACGCCGTGAAGTTCATGGCGCCGCAGTGCGACGTGGTGATCGTGGTCGGCAGCCCGAACAGCTCGAATTCG
AGCCGCCTGCGCGAAGTGGCGGAAAAGCGCGGCGTCGACGCCTATATGGTGGATTCGCCGGACCAGATCGATCCGGCCTG
GGTGGCCGGCAAGCGGCGGATCGGCGTGACCGCCGGCGCGTCGGCGCCGGAGGTGCTGGCCCAGGCGGTGATCGCGCGCC
TGCGTGAACTGGGCGTGCGCAACGTGCGCGCGCTCGAAGGGATCGAGGAAAACGTCTCGTTCCCGCTGCCGCGCGGGCTC
AATCTGCCGCCCGCTGGCTGA

Upstream 100 bases:

>100_bases
TGAAGGAGGTCGGCGAGACCTCGGCGCTGTTCGATTTCAATCACCCGCTTGCGGGGCAGGCCATTACGTTCGAAGTGAAA
ATCATCGGGATCCTGTAACC

Downstream 100 bases:

>100_bases
GCGGCGCCTGCTCCCCGGATCGTCCCGGGCTGCCTCGTCTCGAGCCCGAGCGGGTATCGACTCCTACCAAAGCGCGCTTC
GGCGCGCTTTTGTTTTAGCG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSSTDTLSGPTVAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGSPIYVRHEIVHNKYVVEDLKTKGAIFVEELEEVPS
GNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVEVAKMRQDGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVE
DVLALELPDPERVALVTQTTLSVDDAAEIIAALKRKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
SRLREVAEKRGVDAYMVDSPDQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALEGIEENVSFPLPRGL
NLPPAG

Sequences:

>Translated_326_residues
MSSTDTLSGPTVAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGSPIYVRHEIVHNKYVVEDLKTKGAIFVEELEEVPS
GNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVEVAKMRQDGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVE
DVLALELPDPERVALVTQTTLSVDDAAEIIAALKRKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
SRLREVAEKRGVDAYMVDSPDQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALEGIEENVSFPLPRGL
NLPPAG
>Mature_325_residues
SSTDTLSGPTVAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGSPIYVRHEIVHNKYVVEDLKTKGAIFVEELEEVPSG
NTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVEVAKMRQDGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVED
VLALELPDPERVALVTQTTLSVDDAAEIIAALKRKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSS
RLREVAEKRGVDAYMVDSPDQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALEGIEENVSFPLPRGLN
LPPAG

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=309, Percent_Identity=57.2815533980583, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 35215; Mature: 35084

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTDTLSGPTVAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGSPIYVRHEIVHNKYV
CCCCCCCCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
VEDLKTKGAIFVEELEEVPSGNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVE
HHHHHCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHH
VAKMRQDGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVLALELPDPERVALVTQTT
HHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEE
LSVDDAAEIIAALKRKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEECCCCCCH
SRLREVAEKRGVDAYMVDSPDQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVR
HHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
NVRALEGIEENVSFPLPRGLNLPPAG
HHHHHHCHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSTDTLSGPTVAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGSPIYVRHEIVHNKYV
CCCCCCCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
VEDLKTKGAIFVEELEEVPSGNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVE
HHHHHCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHH
VAKMRQDGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVLALELPDPERVALVTQTT
HHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEE
LSVDDAAEIIAALKRKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEECCCCCCH
SRLREVAEKRGVDAYMVDSPDQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVR
HHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
NVRALEGIEENVSFPLPRGLNLPPAG
HHHHHHCHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA