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The map label for this gene is prlC [H]

Identifier: 238028035

GI number: 238028035

Start: 2824077

End: 2826164

Strand: Direct

Name: prlC [H]

Synonym: bglu_1g24850

Alternate gene names: 238028035

Gene position: 2824077-2826164 (Clockwise)

Preceding gene: 238028034

Following gene: 238028037

Centisome position: 72.29

GC content: 69.44

Gene sequence:

>2088_bases
ATGTCCGTCAGCGCCAACGCCAATCCGCTTCTCGATTTCTCCGGCCTGCCCCGCTTCGCGGAAATCCGTCCCGAGCACGT
GACGCCCGCCCTCGATACGCTGCTCGAGCAGGCCGAGGATGCCGTGGCGCGCGCCGCCGATCCGGCCACGCCCGCCACCT
GGGCCGACGTGGTCGAGACGGTCGAGCGCGTGACCGAGCCGCTCGGCCGCGCCTGGGGCGTGGTCGGCCACCTGAACGCG
GTGGCCGATACGCCCGAGCTGCGCGCCGCCTACGGCGAGAACCTGCCGCGCGTGACCGAGTTCTGGTCGAGCGTGGGGCA
AAACCTTGCGCTCTACGAGAAGTACAAGGCGATCGCAGCCGGCGCCGAATACGCCACGCTCTCGGCCGAGCGCCGCAAGA
TCCTCGACAACTCGCTGCGCGACTTCCGCCTGTCGGGCGCCGAGCTGCCGGAAGACCGCAAGCCGCGCTTCGCCGAGTTG
CAGGAGCAGCAGGCGGCGCTGTCGAAGGCGTTTTCGGATCATGTGCTCGACGCCACCAACGGCTACGCGTACTACGCGCA
GACCGAGGACGAGCTGCGCGGCCTGCCCGACGACGCGATCGCGGCCGCGCGCGAGGCCGCCCAGCGCGAGGACAAGGCCG
GCTGGAAGTTCACGCTGCACTTCCCGTCCTACTTCCCGGTGCTGCAGTACGCCGAGAACCGCGCGATGCGCGAGACGCTC
TACCGCGCCTACGTGACGCGCGCCTCCGAGCTGGGCCCGCAGTACGGCGGCGGCAAGGCCGAATGGGACAACACGAAGAT
CGTCGCCGACACGCTGGCGCTGCGCCGCGAGGAAGCGCAGATGCTCGGCTACGCCAACTTCGCCGAGGTCTCGCTCGCAC
CGAAGATGGCCGAATCGCCGGCCCAGGTCATCGCCTTCCTCGAGGATCTCGCGGTGCGCGCGCGCCCGCATGCCGAGCGC
GACTGGGACGAATTGCGCGCGTTCGCGGCCGACACGCTCGGCCTGCGCGAGCTGGCGCCGTGGGACGTGGCCTATGCCGC
CGAGAAGCTGCGCCAGCAGCGCTACGCGTTCTCGGAAAACGAGGTGAAGCAGTATTTCCCCGAGCCGGCCGTGCTGAAGG
GCCTGTTCACCGTCACCGAGACGCTGTTCGGCGTGAAGATCCGCCGCGACGAGGCGCCGGTCTGGCATCCGGACGTGCGC
TTCTTCCGGGTCGAGAACCCGGACGGCACGCTGGTCGCGCAGTTCTATCTCGACCTCTACGCGCGCGAGGGCAAGCGCGG
CGGCGCCTGGATGGACGACGCACGCTCGCGCGCGAAGCGCGGCACGCTGGTGCAGACGCCGGTGGCCTACCTGACCTGCA
ACTTCTCCGCGCCCGTCGGCGGCAAGCCGGCCTGCTTCACCCACGACGAGGTGATCACGCTGTTCCACGAGTTCGGCCAC
GGACTGCACCACATGCTCACGCGCGTCGAGGAACTCGGCGTGTCGGGCATCAACGGCGTGGAGTGGGACGCCGTGGAGCT
GCCGTCACAGTTCATGGAGAACTTCTGCTGGGAATGGGACGTGCTGCCGTCGATGTCGTCGCATGTCGAGACGGGCGCCT
CGCTGCCGCGCGAACTGTTCGACAAGATGCTGGCCGCGAAGAACTTCCAGAGCGGGCTCGGCACGCTGCGCCAGATCGTG
TTCTCGATGTACGACATGCTGCTGCACGTCGATTTCGATCCGGCCGGCGCGCAGAACGCCGTCGAGTTCGCGCGCGAGAT
CAACGAGCGCTTCCACGTGATCCCGCAGGCGCCGTTCTCGCGCTGGCCGAACACGTTCAGCCACATCTTCGCGGGCGGCT
ACGCGGCCGGCTACTACAGCTACAAGTGGGCCGAGGTGCTGTCGGCCGACGCCTACGCGGCCTTCGAGGAAGCGGCCAAG
GCCGGCGGCACGGTGCTCGACGCCGCCACCGGCACGCGCTACCGCCGCGAGATCCTCGAGGTCGGCGGCAGCCGGCCCGC
GATGGACTCGTTCAAGGCGTTCCGCGGCCGCGAGCCGGAAATCGACGCGCTGCTGCGCCACAACGGCATGACGGCCGCCG
CGCACTGA

Upstream 100 bases:

>100_bases
ACTTCCGATTGGAAACCGGCCGGCCCGCCCCAATAATGTCGTCATGCGGCGGTAGCGCCGCCGCGTCCGTTCATCGCAAT
CCGACCCCGCAGGGAGCCCC

Downstream 100 bases:

>100_bases
GGCCGAGTCCGGGCAGCCGTGCCGCCTGATTCGCCGGGCGGGCGCGGGCTGCCGGCCCGCCGCGCCTCGCTGTACCGAAC
GGCGCCCGGTCATACGGGCG

Product: Oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MSVSANANPLLDFSGLPRFAEIRPEHVTPALDTLLEQAEDAVARAADPATPATWADVVETVERVTEPLGRAWGVVGHLNA
VADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAAGAEYATLSAERRKILDNSLRDFRLSGAELPEDRKPRFAEL
QEQQAALSKAFSDHVLDATNGYAYYAQTEDELRGLPDDAIAAAREAAQREDKAGWKFTLHFPSYFPVLQYAENRAMRETL
YRAYVTRASELGPQYGGGKAEWDNTKIVADTLALRREEAQMLGYANFAEVSLAPKMAESPAQVIAFLEDLAVRARPHAER
DWDELRAFAADTLGLRELAPWDVAYAAEKLRQQRYAFSENEVKQYFPEPAVLKGLFTVTETLFGVKIRRDEAPVWHPDVR
FFRVENPDGTLVAQFYLDLYAREGKRGGAWMDDARSRAKRGTLVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
GLHHMLTRVEELGVSGINGVEWDAVELPSQFMENFCWEWDVLPSMSSHVETGASLPRELFDKMLAAKNFQSGLGTLRQIV
FSMYDMLLHVDFDPAGAQNAVEFAREINERFHVIPQAPFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAK
AGGTVLDAATGTRYRREILEVGGSRPAMDSFKAFRGREPEIDALLRHNGMTAAAH

Sequences:

>Translated_695_residues
MSVSANANPLLDFSGLPRFAEIRPEHVTPALDTLLEQAEDAVARAADPATPATWADVVETVERVTEPLGRAWGVVGHLNA
VADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAAGAEYATLSAERRKILDNSLRDFRLSGAELPEDRKPRFAEL
QEQQAALSKAFSDHVLDATNGYAYYAQTEDELRGLPDDAIAAAREAAQREDKAGWKFTLHFPSYFPVLQYAENRAMRETL
YRAYVTRASELGPQYGGGKAEWDNTKIVADTLALRREEAQMLGYANFAEVSLAPKMAESPAQVIAFLEDLAVRARPHAER
DWDELRAFAADTLGLRELAPWDVAYAAEKLRQQRYAFSENEVKQYFPEPAVLKGLFTVTETLFGVKIRRDEAPVWHPDVR
FFRVENPDGTLVAQFYLDLYAREGKRGGAWMDDARSRAKRGTLVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
GLHHMLTRVEELGVSGINGVEWDAVELPSQFMENFCWEWDVLPSMSSHVETGASLPRELFDKMLAAKNFQSGLGTLRQIV
FSMYDMLLHVDFDPAGAQNAVEFAREINERFHVIPQAPFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAK
AGGTVLDAATGTRYRREILEVGGSRPAMDSFKAFRGREPEIDALLRHNGMTAAAH
>Mature_694_residues
SVSANANPLLDFSGLPRFAEIRPEHVTPALDTLLEQAEDAVARAADPATPATWADVVETVERVTEPLGRAWGVVGHLNAV
ADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAAGAEYATLSAERRKILDNSLRDFRLSGAELPEDRKPRFAELQ
EQQAALSKAFSDHVLDATNGYAYYAQTEDELRGLPDDAIAAAREAAQREDKAGWKFTLHFPSYFPVLQYAENRAMRETLY
RAYVTRASELGPQYGGGKAEWDNTKIVADTLALRREEAQMLGYANFAEVSLAPKMAESPAQVIAFLEDLAVRARPHAERD
WDELRAFAADTLGLRELAPWDVAYAAEKLRQQRYAFSENEVKQYFPEPAVLKGLFTVTETLFGVKIRRDEAPVWHPDVRF
FRVENPDGTLVAQFYLDLYAREGKRGGAWMDDARSRAKRGTLVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGHG
LHHMLTRVEELGVSGINGVEWDAVELPSQFMENFCWEWDVLPSMSSHVETGASLPRELFDKMLAAKNFQSGLGTLRQIVF
SMYDMLLHVDFDPAGAQNAVEFAREINERFHVIPQAPFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAKA
GGTVLDAATGTRYRREILEVGGSRPAMDSFKAFRGREPEIDALLRHNGMTAAAH

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=620, Percent_Identity=31.9354838709677, Blast_Score=294, Evalue=2e-79,
Organism=Homo sapiens, GI14149738, Length=626, Percent_Identity=31.7891373801917, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI156105687, Length=692, Percent_Identity=24.5664739884393, Blast_Score=172, Evalue=7e-43,
Organism=Escherichia coli, GI1789913, Length=687, Percent_Identity=50.2183406113537, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1787819, Length=694, Percent_Identity=30.835734870317, Blast_Score=272, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI71999758, Length=525, Percent_Identity=24.1904761904762, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI32565901, Length=638, Percent_Identity=21.1598746081505, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319793, Length=678, Percent_Identity=28.6135693215339, Blast_Score=276, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6322715, Length=690, Percent_Identity=23.3333333333333, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI21356111, Length=691, Percent_Identity=27.3516642547033, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI20129717, Length=482, Percent_Identity=26.3485477178423, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 77521; Mature: 77389

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSANANPLLDFSGLPRFAEIRPEHVTPALDTLLEQAEDAVARAADPATPATWADVVET
CCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VERVTEPLGRAWGVVGHLNAVADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHC
GAEYATLSAERRKILDNSLRDFRLSGAELPEDRKPRFAELQEQQAALSKAFSDHVLDATN
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GYAYYAQTEDELRGLPDDAIAAAREAAQREDKAGWKFTLHFPSYFPVLQYAENRAMRETL
CEEEEECCHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
YRAYVTRASELGPQYGGGKAEWDNTKIVADTLALRREEAQMLGYANFAEVSLAPKMAESP
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCH
AQVIAFLEDLAVRARPHAERDWDELRAFAADTLGLRELAPWDVAYAAEKLRQQRYAFSEN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCHH
EVKQYFPEPAVLKGLFTVTETLFGVKIRRDEAPVWHPDVRFFRVENPDGTLVAQFYLDLY
HHHHHCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
AREGKRGGAWMDDARSRAKRGTLVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
HHCCCCCCCCHHHHHHHHHCCCEEECCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHH
GLHHMLTRVEELGVSGINGVEWDAVELPSQFMENFCWEWDVLPSMSSHVETGASLPRELF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHH
DKMLAAKNFQSGLGTLRQIVFSMYDMLLHVDFDPAGAQNAVEFAREINERFHVIPQAPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCHH
RWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAKAGGTVLDAATGTRYRREILE
HCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
VGGSRPAMDSFKAFRGREPEIDALLRHNGMTAAAH
CCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVSANANPLLDFSGLPRFAEIRPEHVTPALDTLLEQAEDAVARAADPATPATWADVVET
CCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VERVTEPLGRAWGVVGHLNAVADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHC
GAEYATLSAERRKILDNSLRDFRLSGAELPEDRKPRFAELQEQQAALSKAFSDHVLDATN
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GYAYYAQTEDELRGLPDDAIAAAREAAQREDKAGWKFTLHFPSYFPVLQYAENRAMRETL
CEEEEECCHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
YRAYVTRASELGPQYGGGKAEWDNTKIVADTLALRREEAQMLGYANFAEVSLAPKMAESP
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCH
AQVIAFLEDLAVRARPHAERDWDELRAFAADTLGLRELAPWDVAYAAEKLRQQRYAFSEN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCHH
EVKQYFPEPAVLKGLFTVTETLFGVKIRRDEAPVWHPDVRFFRVENPDGTLVAQFYLDLY
HHHHHCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
AREGKRGGAWMDDARSRAKRGTLVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
HHCCCCCCCCHHHHHHHHHCCCEEECCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHH
GLHHMLTRVEELGVSGINGVEWDAVELPSQFMENFCWEWDVLPSMSSHVETGASLPRELF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHH
DKMLAAKNFQSGLGTLRQIVFSMYDMLLHVDFDPAGAQNAVEFAREINERFHVIPQAPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCHH
RWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAKAGGTVLDAATGTRYRREILE
HCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
VGGSRPAMDSFKAFRGREPEIDALLRHNGMTAAAH
CCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1325967; 8366062; 8041620; 9278503 [H]